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Items: 1 to 20 of 108

1.

Re-evaluation of PD-1 expression by T cells as a marker for immune exhaustion during SIV infection.

Hong JJ, Amancha PK, Rogers K, Ansari AA, Villinger F.

PLoS One. 2013;8(3):e60186. doi: 10.1371/journal.pone.0060186. Epub 2013 Mar 28.

2.

Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination.

Velu V, Kannanganat S, Ibegbu C, Chennareddi L, Villinger F, Freeman GJ, Ahmed R, Amara RR.

J Virol. 2007 Jun;81(11):5819-28. Epub 2007 Mar 21.

3.

In vivo blockade of the programmed cell death-1 pathway using soluble recombinant PD-1-Fc enhances CD4+ and CD8+ T cell responses but has limited clinical benefit.

Amancha PK, Hong JJ, Rogers K, Ansari AA, Villinger F.

J Immunol. 2013 Dec 15;191(12):6060-70. doi: 10.4049/jimmunol.1302044. Epub 2013 Nov 13.

4.

Diminished viral control during simian immunodeficiency virus infection is associated with aberrant PD-1hi CD4 T cell enrichment in the lymphoid follicles of the rectal mucosa.

Mylvaganam GH, Velu V, Hong JJ, Sadagopal S, Kwa S, Basu R, Lawson B, Villinger F, Amara RR.

J Immunol. 2014 Nov 1;193(9):4527-36. doi: 10.4049/jimmunol.1401222. Epub 2014 Sep 22.

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Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression.

Xu H, Wang X, Pahar B, Moroney-Rasmussen T, Alvarez X, Lackner AA, Veazey RS.

J Immunol. 2010 Dec 15;185(12):7340-8. doi: 10.4049/jimmunol.1001642. Epub 2010 Nov 8.

7.

Soluble PD-1 rescues the proliferative response of simian immunodeficiency virus-specific CD4 and CD8 T cells during chronic infection.

Onlamoon N, Rogers K, Mayne AE, Pattanapanyasat K, Mori K, Villinger F, Ansari AA.

Immunology. 2008 Jun;124(2):277-93. doi: 10.1111/j.1365-2567.2007.02766.x. Epub 2008 Feb 5.

8.

High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance.

Petrovas C, Yamamoto T, Price DA, Rao SS, Klatt NR, Brenchley JM, Douek DC, Gostick E, Angermann BR, Grossman Z, Macallan DC, Meier-Schellersheim M, Koup RA.

J Virol. 2013 Sep;87(17):9836-44. doi: 10.1128/JVI.01001-13. Epub 2013 Jul 3.

9.

SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection.

Petrovas C, Price DA, Mattapallil J, Ambrozak DR, Geldmacher C, Cecchinato V, Vaccari M, Tryniszewska E, Gostick E, Roederer M, Douek DC, Morgan SH, Davis SJ, Franchini G, Koup RA.

Blood. 2007 Aug 1;110(3):928-36. Epub 2007 Apr 17.

10.

Divergent kinetics of proliferating T cell subsets in simian immunodeficiency virus (SIV) infection: SIV eliminates the "first responder" CD4+ T cells in primary infection.

Wang X, Xu H, Pahar B, Lackner AA, Veazey RS.

J Virol. 2013 Jun;87(12):7032-8. doi: 10.1128/JVI.00027-13. Epub 2013 Apr 17.

11.

Increased loss of CCR5+ CD45RA- CD4+ T cells in CD8+ lymphocyte-depleted Simian immunodeficiency virus-infected rhesus monkeys.

Veazey RS, Acierno PM, McEvers KJ, Baumeister SH, Foster GJ, Rett MD, Newberg MH, Kuroda MJ, Williams K, Kim EY, Wolinsky SM, Rieber EP, Piatak M Jr, Lifson JD, Montefiori DC, Brown CR, Hirsch VM, Schmitz JE.

J Virol. 2008 Jun;82(11):5618-30. doi: 10.1128/JVI.02748-07. Epub 2008 Mar 26.

12.

CD8+ T cell dynamics during primary simian immunodeficiency virus infection in macaques: relationship of effector cell differentiation with the extent of viral replication.

Monceaux V, Viollet L, Petit F, Ho Tsong Fang R, Cumont MC, Zaunders J, Hurtrel B, Estaquier J.

J Immunol. 2005 Jun 1;174(11):6898-908.

13.

Blockade of T cell costimulation reveals interrelated actions of CD4+ and CD8+ T cells in control of SIV replication.

Garber DA, Silvestri G, Barry AP, Fedanov A, Kozyr N, McClure H, Montefiori DC, Larsen CP, Altman JD, Staprans SI, Feinberg MB.

J Clin Invest. 2004 Mar;113(6):836-45.

14.

Inhibitory TCR coreceptor PD-1 is a sensitive indicator of low-level replication of SIV and HIV-1.

Salisch NC, Kaufmann DE, Awad AS, Reeves RK, Tighe DP, Li Y, Piatak M Jr, Lifson JD, Evans DT, Pereyra F, Freeman GJ, Johnson RP.

J Immunol. 2010 Jan 1;184(1):476-87. doi: 10.4049/jimmunol.0902781. Epub 2009 Nov 30.

15.

IL-15 treatment during acute simian immunodeficiency virus (SIV) infection increases viral set point and accelerates disease progression despite the induction of stronger SIV-specific CD8+ T cell responses.

Mueller YM, Do DH, Altork SR, Artlett CM, Gracely EJ, Katsetos CD, Legido A, Villinger F, Altman JD, Brown CR, Lewis MG, Katsikis PD.

J Immunol. 2008 Jan 1;180(1):350-60.

16.

Differential CD4+ T-lymphocyte apoptosis and bystander T-cell activation in rhesus macaques and sooty mangabeys during acute simian immunodeficiency virus infection.

Meythaler M, Martinot A, Wang Z, Pryputniewicz S, Kasheta M, Ling B, Marx PA, O'Neil S, Kaur A.

J Virol. 2009 Jan;83(2):572-83. doi: 10.1128/JVI.01715-08. Epub 2008 Nov 5.

17.

Normal T-cell turnover in sooty mangabeys harboring active simian immunodeficiency virus infection.

Chakrabarti LA, Lewin SR, Zhang L, Gettie A, Luckay A, Martin LN, Skulsky E, Ho DD, Cheng-Mayer C, Marx PA.

J Virol. 2000 Feb;74(3):1209-23.

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