Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 74

1.

Metabolism of BYZX in human liver microsomes and cytosol: identification of the metabolites and metabolic pathways of BYZX.

Yu L, Jiang Y, Wang L, Sheng R, Hu Y, Zeng S.

PLoS One. 2013;8(3):e59882. doi: 10.1371/journal.pone.0059882. Epub 2013 Mar 29.

2.

In vitro metabolism of BYZX in human liver microsomes and the structural elucidation of metabolite by liquid chromatography-mass spectrometry method.

Xia ZL, Ying JY, Sheng R, Zeng S, Hu YZ, Yao TW.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 1;857(2):266-74. Epub 2007 Jul 31.

PMID:
17709305
4.

In vitro studies on the oxidative metabolism of 20(s)-ginsenoside Rh2 in human, monkey, dog, rat, and mouse liver microsomes, and human liver s9.

Li L, Chen X, Zhou J, Zhong D.

Drug Metab Dispos. 2012 Oct;40(10):2041-53. doi: 10.1124/dmd.112.046995. Epub 2012 Jul 24.

5.

Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.

Niwa T, Shiraga T, Mitani Y, Terakawa M, Tokuma Y, Kagayama A.

Drug Metab Dispos. 2000 Sep;28(9):1128-34.

6.

[Interaction between (E)-2-(4-(diethylamino methyl) benzylidene)-5,6-dimethoxy-2,3-dihydroinden-one and P-glycoprotein].

Xia ZL, Ying JY, Sun F, Zeng S, Yao TW.

Yao Xue Xue Bao. 2007 Dec;42(12):1298-302. Chinese.

PMID:
18338644
7.

Novel metabolites of buprenorphine detected in human liver microsomes and human urine.

Chang Y, Moody DE, McCance-Katz EF.

Drug Metab Dispos. 2006 Mar;34(3):440-8. Epub 2005 Dec 28.

8.
9.

In vitro metabolism of chloroquine: identification of CYP2C8, CYP3A4, and CYP2D6 as the main isoforms catalyzing N-desethylchloroquine formation.

Projean D, Baune B, Farinotti R, Flinois JP, Beaune P, Taburet AM, Ducharme J.

Drug Metab Dispos. 2003 Jun;31(6):748-54.

10.

In vitro biotransformation of a novel antimalarial cysteine protease inhibitor in human liver microsomes.

Zhang Y, Guo X, Lin ET, Benet LZ.

Pharmacology. 1999 Mar;58(3):147-59.

PMID:
9925971
12.

In vitro identification of metabolic pathways and cytochrome P450 enzymes involved in the metabolism of etoperidone.

Yan Z, Caldwell GW, Wu WN, McKown LA, Rafferty B, Jones W, Masucci JA.

Xenobiotica. 2002 Nov;32(11):949-62.

PMID:
12487725
13.

Characterization of human cytochrome P450 isoforms involved in the metabolism of 7-epi-paclitaxel.

Zhang YY, Liu Y, Zhang JW, Ge GB, Wang LM, Sun J, Yang L.

Xenobiotica. 2009 Apr;39(4):283-92. doi: 10.1080/00498250802714907.

PMID:
19350451
15.

CYP2C8 and CYP3A4 are the principal enzymes involved in the human in vitro biotransformation of the insulin secretagogue repaglinide.

Bidstrup TB, Bjørnsdottir I, Sidelmann UG, Thomsen MS, Hansen KT.

Br J Clin Pharmacol. 2003 Sep;56(3):305-14.

16.

Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543.

Khojasteh-Bakht SC, Rossulek MI, Fouda HG, Prakash C.

Xenobiotica. 2003 Dec;33(12):1201-10.

PMID:
14742142
17.
18.

Cytochrome P450 2B6 catalyzes the formation of pharmacologically active sibutramine (N-{1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine) metabolites in human liver microsomes.

Bae SK, Cao S, Seo KA, Kim H, Kim MJ, Shon JH, Liu KH, Zhou HH, Shin JG.

Drug Metab Dispos. 2008 Aug;36(8):1679-88. doi: 10.1124/dmd.108.020727. Epub 2008 May 12.

19.

Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate.

Li XQ, Björkman A, Andersson TB, Ridderström M, Masimirembwa CM.

J Pharmacol Exp Ther. 2002 Feb;300(2):399-407.

20.

Comparative metabolism of four limonoids in human liver microsomes using ultra-high-performance liquid chromatography coupled with high-resolution LTQ-Orbitrap mass spectrometry.

Ren W, Xin SK, Han LY, Zuo R, Li Y, Gong MX, Wei XL, Zhou YY, He J, Wang HJ, Si N, Zhao HY, Yang J, Bian BL.

Rapid Commun Mass Spectrom. 2015 Nov 15;29(21):2045-56. doi: 10.1002/rcm.7365.

PMID:
26443405

Supplemental Content

Support Center