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Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy.

Kim SJ, Syed GH, Siddiqui A.

PLoS Pathog. 2013 Mar;9(3):e1003285. doi: 10.1371/journal.ppat.1003285. Epub 2013 Mar 28.


Hepatitis C virus core protein suppresses mitophagy by interacting with parkin in the context of mitochondrial depolarization.

Hara Y, Yanatori I, Ikeda M, Kiyokage E, Nishina S, Tomiyama Y, Toida K, Kishi F, Kato N, Imamura M, Chayama K, Hino K.

Am J Pathol. 2014 Nov;184(11):3026-39. doi: 10.1016/j.ajpath.2014.07.024. Epub 2014 Sep 20.


Hepatitis B virus disrupts mitochondrial dynamics: induces fission and mitophagy to attenuate apoptosis.

Kim SJ, Khan M, Quan J, Till A, Subramani S, Siddiqui A.

PLoS Pathog. 2013;9(12):e1003722. doi: 10.1371/journal.ppat.1003722. Epub 2013 Dec 5.


CSFV induced mitochondrial fission and mitophagy to inhibit apoptosis.

Gou H, Zhao M, Xu H, Yuan J, He W, Zhu M, Ding H, Yi L, Chen J.

Oncotarget. 2017 Jun 13;8(24):39382-39400. doi: 10.18632/oncotarget.17030.


Nitric oxide induction of Parkin translocation in PTEN-induced putative kinase 1 (PINK1) deficiency: functional role of neuronal nitric oxide synthase during mitophagy.

Han JY, Kang MJ, Kim KH, Han PL, Kim HS, Ha JY, Son JH.

J Biol Chem. 2015 Apr 17;290(16):10325-35. doi: 10.1074/jbc.M114.624767. Epub 2015 Feb 25.


PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy.

Shiba-Fukushima K, Imai Y, Yoshida S, Ishihama Y, Kanao T, Sato S, Hattori N.

Sci Rep. 2012;2:1002. doi: 10.1038/srep01002. Epub 2012 Dec 19.


ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts.

Qi Y, Qiu Q, Gu X, Tian Y, Zhang Y.

Sci Rep. 2016 Apr 19;6:24700. doi: 10.1038/srep24700.


Reactive oxygen species trigger Parkin/PINK1 pathway-dependent mitophagy by inducing mitochondrial recruitment of Parkin.

Xiao B, Goh JY, Xiao L, Xian H, Lim KL, Liou YC.

J Biol Chem. 2017 Oct 6;292(40):16697-16708. doi: 10.1074/jbc.M117.787739. Epub 2017 Aug 28.


Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy.

Ivankovic D, Chau KY, Schapira AH, Gegg ME.

J Neurochem. 2016 Jan;136(2):388-402. doi: 10.1111/jnc.13412. Epub 2015 Nov 24.


Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway.

Yin J, Guo J, Zhang Q, Cui L, Zhang L, Zhang T, Zhao J, Li J, Middleton A, Carmichael PL, Peng S.

Toxicol In Vitro. 2018 Sep;51:1-10. doi: 10.1016/j.tiv.2018.05.001. Epub 2018 May 3.


The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications.

Durcan TM, Fon EA.

Genes Dev. 2015 May 15;29(10):989-99. doi: 10.1101/gad.262758.115. Review.


MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5.

Nezich CL, Wang C, Fogel AI, Youle RJ.

J Cell Biol. 2015 Aug 3;210(3):435-50. doi: 10.1083/jcb.201501002.


PINK1/Parkin-mediated mitophagy was activated against 1,4-Benzoquinone-induced apoptosis in HL-60 cells.

Zhang C, Yu X, Gao J, Zhang Q, Sun S, Zhu H, Yang X, Yan H.

Toxicol In Vitro. 2018 Aug;50:217-224. doi: 10.1016/j.tiv.2018.03.002. Epub 2018 Mar 20.


Cadmium induces mitophagy through ROS-mediated PINK1/Parkin pathway.

Wei X, Qi Y, Zhang X, Qiu Q, Gu X, Tao C, Huang D, Zhang Y.

Toxicol Mech Methods. 2014 Oct;24(7):504-11. doi: 10.3109/15376516.2014.943444. Epub 2014 Sep 11.


Acetylcholine Attenuates Hypoxia/Reoxygenation Injury by Inducing Mitophagy Through PINK1/Parkin Signal Pathway in H9c2 Cells.

Sun L, Zhao M, Yang Y, Xue RQ, Yu XJ, Liu JK, Zang WJ.

J Cell Physiol. 2016 May;231(5):1171-81. doi: 10.1002/jcp.25215. Epub 2015 Oct 23.


Ethanol-induced mitophagy in liver is associated with activation of the PINK1-Parkin pathway triggered by oxidative DNA damage.

Eid N, Ito Y, Horibe A, Otsuki Y.

Histol Histopathol. 2016 Oct;31(10):1143-59. doi: 10.14670/HH-11-747. Epub 2016 Mar 3.


Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin.

Ashrafi G, Schlehe JS, LaVoie MJ, Schwarz TL.

J Cell Biol. 2014 Sep 1;206(5):655-70. doi: 10.1083/jcb.201401070. Epub 2014 Aug 25.


Pink1/Parkin-mediated mitophagy play a protective role in cisplatin induced renal tubular epithelial cells injury.

Zhao C, Chen Z, Xu X, An X, Duan S, Huang Z, Zhang C, Wu L, Zhang B, Zhang A, Xing C, Yuan Y.

Exp Cell Res. 2017 Jan 15;350(2):390-397. doi: 10.1016/j.yexcr.2016.12.015. Epub 2016 Dec 23.


Regulation by mitophagy.

Hattori N, Saiki S, Imai Y.

Int J Biochem Cell Biol. 2014 Aug;53:147-50. doi: 10.1016/j.biocel.2014.05.012. Epub 2014 May 16. Review.


Peroxiredoxin 6 Is a Crucial Factor in the Initial Step of Mitochondrial Clearance and Is Upstream of the PINK1-Parkin Pathway.

Ma S, Zhang X, Zheng L, Li Z, Zhao X, Lai W, Shen H, Lv J, Yang G, Wang Q, Ji J.

Antioxid Redox Signal. 2016 Mar 20;24(9):486-501. doi: 10.1089/ars.2015.6336. Epub 2016 Feb 19.


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