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Items: 1 to 20 of 76

1.

NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM.

Osborne JK, Larsen JE, Shields MD, Gonzales JX, Shames DS, Sato M, Kulkarni A, Wistuba II, Girard L, Minna JD, Cobb MH.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6524-9. doi: 10.1073/pnas.1303932110. Epub 2013 Apr 3.

2.

NeuroD1 mediates nicotine-induced migration and invasion via regulation of the nicotinic acetylcholine receptor subunits in a subset of neural and neuroendocrine carcinomas.

Osborne JK, Guerra ML, Gonzales JX, McMillan EA, Minna JD, Cobb MH.

Mol Biol Cell. 2014 Jun;25(11):1782-92. doi: 10.1091/mbc.E13-06-0316. Epub 2014 Apr 9.

3.

NeuroD1 regulation of migration accompanies the differential sensitivity of neuroendocrine carcinomas to TrkB inhibition.

Osborne JK, Larsen JE, Gonzales JX, Shames DS, Sato M, Wistuba II, Girard L, Minna JD, Cobb MH.

Oncogenesis. 2013 Aug 19;2:e63. doi: 10.1038/oncsis.2013.24.

4.

Neural cell adhesion molecules (NCAM) and NCAM-PSA expression in neuroendocrine lung tumors.

Lantuejoul S, Moro D, Michalides RJ, Brambilla C, Brambilla E.

Am J Surg Pathol. 1998 Oct;22(10):1267-76.

PMID:
9777989
5.

The neural cell adhesion molecule is involved in the metastatic capacity in a murine model of lung cancer.

Campodónico PB, de Kier Joffé ED, Urtreger AJ, Lauria LS, Lastiri JM, Puricelli LI, Todaro LB.

Mol Carcinog. 2010 Apr;49(4):386-97. doi: 10.1002/mc.20611.

PMID:
20191608
6.

Binding of the receptor tyrosine kinase TrkB to the neural cell adhesion molecule (NCAM) regulates phosphorylation of NCAM and NCAM-dependent neurite outgrowth.

Cassens C, Kleene R, Xiao MF, Friedrich C, Dityateva G, Schafer-Nielsen C, Schachner M.

J Biol Chem. 2010 Sep 10;285(37):28959-67. doi: 10.1074/jbc.M110.114835. Epub 2010 Jul 6.

7.

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers.

Augustyn A, Borromeo M, Wang T, Fujimoto J, Shao C, Dospoy PD, Lee V, Tan C, Sullivan JP, Larsen JE, Girard L, Behrens C, Wistuba II, Xie Y, Cobb MH, Gazdar AF, Johnson JE, Minna JD.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14788-93. doi: 10.1073/pnas.1410419111. Epub 2014 Sep 29.

8.

POU domain transcription factor BRN2 is crucial for expression of ASCL1, ND1 and neuroendocrine marker molecules and cell growth in small cell lung cancer.

Ishii J, Sato H, Sakaeda M, Shishido-Hara Y, Hiramatsu C, Kamma H, Shimoyamada H, Fujiwara M, Endo T, Aoki I, Yazawa T.

Pathol Int. 2013 Mar;63(3):158-68. doi: 10.1111/pin.12042.

PMID:
23530560
9.

Basic helix-loop-helix transcription factor profiling of lung tumors shows aberrant expression of the proneural gene atonal homolog 1 (ATOH1, HATH1, MATH1) in neuroendocrine tumors.

Westerman BA, Breuer RH, Poutsma A, Chhatta A, Noorduyn LA, Koolen MG, Postmus PE, Blankenstein MA, Oudejans CB.

Int J Biol Markers. 2007 Apr-Jun;22(2):114-23.

PMID:
17549667
10.

TrkB/BDNF signaling pathway is a potential therapeutic target for pulmonary large cell neuroendocrine carcinoma.

Odate S, Nakamura K, Onishi H, Kojima M, Uchiyama A, Nakano K, Kato M, Tanaka M, Katano M.

Lung Cancer. 2013 Mar;79(3):205-14. doi: 10.1016/j.lungcan.2012.12.004. Epub 2013 Jan 9.

PMID:
23312550
11.

Neuroendocrine cancer-specific up-regulating mechanism of insulin-like growth factor binding protein-2 in small cell lung cancer.

Yazawa T, Sato H, Shimoyamada H, Okudela K, Woo T, Tajiri M, Ogura T, Ogawa N, Suzuki T, Mitsui H, Ishii J, Miyata C, Sakaeda M, Goto K, Kashiwagi K, Masuda M, Takahashi T, Kitamura H.

Am J Pathol. 2009 Sep;175(3):976-87. doi: 10.2353/ajpath.2009.081004. Epub 2009 Aug 13.

12.

Class III/IV POU transcription factors expressed in small cell lung cancer cells are involved in proneural/neuroendocrine differentiation.

Ishii J, Sato H, Yazawa T, Shishido-Hara Y, Hiramatsu C, Nakatani Y, Kamma H.

Pathol Int. 2014 Sep;64(9):415-22. doi: 10.1111/pin.12198.

PMID:
25243889
13.

Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis.

Sinkevicius KW, Kriegel C, Bellaria KJ, Lee J, Lau AN, Leeman KT, Zhou P, Beede AM, Fillmore CM, Caswell D, Barrios J, Wong KK, Sholl LM, Schlaeger TM, Bronson RT, Chirieac LR, Winslow MM, Haigis MC, Kim CF.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10299-304. doi: 10.1073/pnas.1404399111. Epub 2014 Jun 30.

14.

CD44 and its v6 spliced variant in lung carcinomas: relation to NCAM, CEA, EMA and UP1 and prognostic significance.

Nguyen VN, Mirejovský T, Melinová L, Mandys V.

Neoplasma. 2000;47(6):400-8.

PMID:
11263866
15.

[Expression and clinicopathologic significance of human achaete-scute homolog 1 in pulmonary neuroendocrine tumors].

Li F, Zhong Z, Li R, Huang H, Wang L, Zheng D, Zhang D.

Zhongguo Fei Ai Za Zhi. 2010 Apr;13(4):317-21. doi: 10.3779/j.issn.1009-3419.2010.04.09. Chinese.

16.

NCAM polysialylation during adherence transitions: live cell monitoring using an antibody-mimetic EGFP-endosialidase and the viability dye DRAQ7.

Smith PJ, Furon E, Wiltshire M, Chappell S, Patterson LH, Shnyder SD, Falconer RA, Errington RJ.

Cytometry A. 2013 Jul;83(7):659-71. doi: 10.1002/cyto.a.22306. Epub 2013 May 28.

17.

Cooperation of tyrosine kinase receptor TrkB and epidermal growth factor receptor signaling enhances migration and dispersal of lung tumor cells.

Götz R, Sendtner M.

PLoS One. 2014 Jun 24;9(6):e100944. doi: 10.1371/journal.pone.0100944. eCollection 2014.

18.

Analysis of tyrosine phosphorylation-dependent protein-protein interactions in TrkB-mediated intracellular signaling using modified yeast two-hybrid system.

Yamada M, Suzuki K, Mizutani M, Asada A, Matozaki T, Ikeuchi T, Koizumi S, Hatanaka H.

J Biochem. 2001 Jul;130(1):157-65.

19.

hASH1 expression is closely correlated with endocrine phenotype and differentiation extent in pulmonary neuroendocrine tumors.

Jiang SX, Kameya T, Asamura H, Umezawa A, Sato Y, Shinada J, Kawakubo Y, Igarashi T, Nagai K, Okayasu I.

Mod Pathol. 2004 Feb;17(2):222-9.

20.

Neural cell adhesion molecule in breast, colon and lung carcinomas.

Zołtowska A, Stepiński J, Lewko B, Serkies K, Zamorska B, Roszkiewicz A, Izycka-Swieszewska E, Kruszewski WJ.

Arch Immunol Ther Exp (Warsz). 2001;49(2):171-4.

PMID:
11348022

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