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Items: 1 to 20 of 203


DNA-dependent activator of interferon-regulatory factors (DAI) promotes lupus nephritis by activating the calcium pathway.

Zhang W, Zhou Q, Xu W, Cai Y, Yin Z, Gao X, Xiong S.

J Biol Chem. 2013 May 10;288(19):13534-50. doi: 10.1074/jbc.M113.457218. Epub 2013 Apr 3.


Macrophage differentiation and polarization via phosphatidylinositol 3-kinase/Akt-ERK signaling pathway conferred by serum amyloid P component.

Zhang W, Xu W, Xiong S.

J Immunol. 2011 Aug 15;187(4):1764-77. doi: 10.4049/jimmunol.1002315. Epub 2011 Jul 13.


Blockade of Notch1 signaling alleviates murine lupus via blunting macrophage activation and M2b polarization.

Zhang W, Xu W, Xiong S.

J Immunol. 2010 Jun 1;184(11):6465-78. doi: 10.4049/jimmunol.0904016. Epub 2010 Apr 28.


Mannose-binding lectin blunts macrophage polarization and ameliorates lupus nephritis.

Cai Y, Zhang W, Xiong S.

PLoS One. 2013 Apr 23;8(4):e62465. doi: 10.1371/journal.pone.0062465. Print 2013.


Dynamic expression of microRNAs in M2b polarized macrophages associated with systemic lupus erythematosus.

Xiao P, Dong C, Yue Y, Xiong S.

Gene. 2014 Sep 1;547(2):300-9. doi: 10.1016/j.gene.2014.06.065. Epub 2014 Jun 30.


AIM2 facilitates the apoptotic DNA-induced systemic lupus erythematosus via arbitrating macrophage functional maturation.

Zhang W, Cai Y, Xu W, Yin Z, Gao X, Xiong S.

J Clin Immunol. 2013 Jul;33(5):925-37. doi: 10.1007/s10875-013-9881-6. Epub 2013 Mar 12.


Granulin exacerbates lupus nephritis via enhancing macrophage M2b polarization.

Chen X, Wen Z, Xu W, Xiong S.

PLoS One. 2013 Jun 5;8(6):e65542. doi: 10.1371/journal.pone.0065542. Print 2013.


Amelioration of lupus nephritis by serum amyloid P component gene therapy with distinct mechanisms varied from different stage of the disease.

Zhang W, Wu J, Qiao B, Xu W, Xiong S.

PLoS One. 2011;6(7):e22659. doi: 10.1371/journal.pone.0022659. Epub 2011 Jul 25.


Macrophage Polarization Modulates Development of Systemic Lupus Erythematosus.

Li F, Yang Y, Zhu X, Huang L, Xu J.

Cell Physiol Biochem. 2015;37(4):1279-88. doi: 10.1159/000430251. Epub 2015 Oct 5.


TIPE2 Alleviates Systemic Lupus Erythematosus Through Regulating Macrophage Polarization.

Li F, Zhu X, Yang Y, Huang L, Xu J.

Cell Physiol Biochem. 2016;38(1):330-9. doi: 10.1159/000438633. Epub 2016 Jan 29.


Identification of Cyclin-Dependent Kinase 1 as a Novel Regulator of Type I Interferon Signaling in Systemic Lupus Erythematosus.

Wu L, Qin Y, Xia S, Dai M, Han X, Wu Y, Zhang X, Ma J, Wang Y, Tang Y, Liu Z, Zhu W, Jallal B, Yao Y, Qu B, Shen N.

Arthritis Rheumatol. 2016 May;68(5):1222-32. doi: 10.1002/art.39543.


Induction of systemic lupus erythematosus-like syndrome in syngeneic mice by immunization with activated lymphocyte-derived DNA.

Qiao B, Wu J, Chu YW, Wang Y, Wang DP, Wu HS, Xiong SD.

Rheumatology (Oxford). 2005 Sep;44(9):1108-14. Epub 2005 Apr 19.


Neutrophil Extracellular Trap Mitochondrial DNA and Its Autoantibody in Systemic Lupus Erythematosus and a Proof-of-Concept Trial of Metformin.

Wang H, Li T, Chen S, Gu Y, Ye S.

Arthritis Rheumatol. 2015 Dec;67(12):3190-200. doi: 10.1002/art.39296.


C-reactive protein functions as a negative regulator of macrophage activation induced by apoptotic DNA.

Zhang W, Cai Y, Xu W, Xiong S.

Protein Cell. 2011 Aug;2(8):672-9. doi: 10.1007/s13238-011-1084-4. Epub 2011 Sep 9.


DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.

Takaoka A, Wang Z, Choi MK, Yanai H, Negishi H, Ban T, Lu Y, Miyagishi M, Kodama T, Honda K, Ohba Y, Taniguchi T.

Nature. 2007 Jul 26;448(7152):501-5. Epub 2007 Jul 8.


Laquinimod delays and suppresses nephritis in lupus-prone mice and affects both myeloid and lymphoid immune cells.

Lourenço EV, Wong M, Hahn BH, Palma-Diaz MF, Skaggs BJ.

Arthritis Rheumatol. 2014 Mar;66(3):674-85. doi: 10.1002/art.38259.


Mdm2 promotes systemic lupus erythematosus and lupus nephritis.

Allam R, Sayyed SG, Kulkarni OP, Lichtnekert J, Anders HJ.

J Am Soc Nephrol. 2011 Nov;22(11):2016-27. doi: 10.1681/ASN.2011010045. Epub 2011 Sep 23.


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