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Items: 1 to 20 of 170

1.

Melatonin antagonizes hypoxia-mediated glioblastoma cell migration and invasion via inhibition of HIF-1α.

Zhang Y, Liu Q, Wang F, Ling EA, Liu S, Wang L, Yang Y, Yao L, Chen X, Wang F, Shi W, Gao M, Hao A.

J Pineal Res. 2013 Sep;55(2):121-30. doi: 10.1111/jpi.12052. Epub 2013 Mar 29.

PMID:
23551342
2.

Silencing hypoxia-inducible factor-1alpha inhibits cell migration and invasion under hypoxic environment in malignant gliomas.

Fujiwara S, Nakagawa K, Harada H, Nagato S, Furukawa K, Teraoka M, Seno T, Oka K, Iwata S, Ohnishi T.

Int J Oncol. 2007 Apr;30(4):793-802.

PMID:
17332917
3.

SNS-032 prevents hypoxia-mediated glioblastoma cell invasion by inhibiting hypoxia inducible factor-1alpha expression.

Ali MA, Reis A, Ding LH, Story MD, Habib AA, Chattopadhyay A, Saha D.

Int J Oncol. 2009 Apr;34(4):1051-60.

PMID:
19287962
4.

RNAi Knockdown of Hypoxia-Inducible Factor-1α Decreased the Proliferation, Migration, and Invasion of Hypoxic Hepatocellular Carcinoma Cells.

Chen C, Liu R, Wang J, Yan Z, Qian S, Zhang W.

Cell Biochem Biophys. 2015 Apr;71(3):1677-84. doi: 10.1007/s12013-014-0390-x.

PMID:
25388848
5.

Hypoxia suppresses E-cadherin and enhances matrix metalloproteinase-2 expression favoring esophageal carcinoma migration and invasion via hypoxia inducible factor-1 alpha activation.

Jing SW, Wang YD, Chen LQ, Sang MX, Zheng MM, Sun GG, Liu Q, Cheng YJ, Yang CR.

Dis Esophagus. 2013 Jan;26(1):75-83. doi: 10.1111/j.1442-2050.2011.01321.x. Epub 2012 Feb 17.

PMID:
22340517
6.

Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion.

Zhou X, Liu Z, Shi Q, Jiao J, Bian W, Song X, Mo J, Sang B, Xu Y, Qian J, Chao Y, Yu R.

J Neurooncol. 2013 May;112(3):365-74. doi: 10.1007/s11060-013-1081-y. Epub 2013 Mar 9.

PMID:
23475391
7.

Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion.

Zagzag D, Lukyanov Y, Lan L, Ali MA, Esencay M, Mendez O, Yee H, Voura EB, Newcomb EW.

Lab Invest. 2006 Dec;86(12):1221-32. Epub 2006 Oct 30.

8.

Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cells.

Cho SY, Lee HJ, Jeong SJ, Lee HJ, Kim HS, Chen CY, Lee EO, Kim SH.

J Pineal Res. 2011 Aug;51(1):87-93. doi: 10.1111/j.1600-079X.2011.00865.x. Epub 2011 Mar 11.

PMID:
21392092
9.

Melatonin suppresses tumor angiogenesis by inhibiting HIF-1alpha stabilization under hypoxia.

Park SY, Jang WJ, Yi EY, Jang JY, Jung Y, Jeong JW, Kim YJ.

J Pineal Res. 2010 Mar;48(2):178-84.

PMID:
20449875
10.

Effect of silencing HIF-1α on proliferation, invasion and migration of glioblastoma U87 cells.

Shen SH, Kwan AL, Chen YY, Wang ZX.

Neurol Sci. 2013 Mar;34(3):365-71. doi: 10.1007/s10072-012-1010-4. Epub 2012 Mar 28.

PMID:
22454035
11.

Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3.

Boreddy SR, Sahu RP, Srivastava SK.

PLoS One. 2011;6(10):e25799. doi: 10.1371/journal.pone.0025799. Epub 2011 Oct 10.

12.

Anti-invasive effects of celastrol in hypoxia-induced fibroblast-like synoviocyte through suppressing of HIF-1α/CXCR4 signaling pathway.

Li GQ, Liu D, Zhang Y, Qian YY, Zhu YD, Guo SY, Sunagawa M, Hisamitsu T, Liu YQ.

Int Immunopharmacol. 2013 Dec;17(4):1028-36. doi: 10.1016/j.intimp.2013.10.006. Epub 2013 Oct 18.

PMID:
24144813
13.

Knockdown of Nrf2 suppresses glioblastoma angiogenesis by inhibiting hypoxia-induced activation of HIF-1α.

Ji X, Wang H, Zhu J, Zhu L, Pan H, Li W, Zhou Y, Cong Z, Yan F, Chen S.

Int J Cancer. 2014 Aug 1;135(3):574-84. doi: 10.1002/ijc.28699. Epub 2014 Jan 10.

14.

Hypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation.

Asnaghi L, Lin MH, Lim KS, Lim KJ, Tripathy A, Wendeborn M, Merbs SL, Handa JT, Sodhi A, Bar EE, Eberhart CG.

PLoS One. 2014 Aug 28;9(8):e105372. doi: 10.1371/journal.pone.0105372. eCollection 2014.

15.
16.

Interleukin-17A promotes rheumatoid arthritis synoviocytes migration and invasion under hypoxia by increasing MMP2 and MMP9 expression through NF-κB/HIF-1α pathway.

Li G, Zhang Y, Qian Y, Zhang H, Guo S, Sunagawa M, Hisamitsu T, Liu Y.

Mol Immunol. 2013 Mar;53(3):227-36. doi: 10.1016/j.molimm.2012.08.018. Epub 2012 Sep 5.

PMID:
22960198
17.

HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs).

De Francesco EM, Lappano R, Santolla MF, Marsico S, Caruso A, Maggiolini M.

Breast Cancer Res. 2013;15(4):R64.

18.

The Apoptotic Effect of HIF-1α Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions.

Tanaka T, Kitajima Y, Miyake S, Yanagihara K, Hara H, Nishijima-Matsunobu A, Baba K, Shida M, Wakiyama K, Nakamura J, Noshiro H.

PLoS One. 2015 Sep 4;10(9):e0137257. doi: 10.1371/journal.pone.0137257. eCollection 2015.

19.

Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres.

Méndez O, Zavadil J, Esencay M, Lukyanov Y, Santovasi D, Wang SC, Newcomb EW, Zagzag D.

Mol Cancer. 2010 Jun 1;9:133. doi: 10.1186/1476-4598-9-133.

20.

Blockage of Nrf2 suppresses the migration and invasion of esophageal squamous cell carcinoma cells in hypoxic microenvironment.

Shen H, Yang Y, Xia S, Rao B, Zhang J, Wang J.

Dis Esophagus. 2014 Sep-Oct;27(7):685-92. doi: 10.1111/dote.12124. Epub 2013 Sep 13.

PMID:
24028437

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