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Items: 1 to 20 of 106

1.

Hepatic glucose sensing is required to preserve β cell glucose competence.

Seyer P, Vallois D, Poitry-Yamate C, Schütz F, Metref S, Tarussio D, Maechler P, Staels B, Lanz B, Grueter R, Decaris J, Turner S, da Costa A, Preitner F, Minehira K, Foretz M, Thorens B.

J Clin Invest. 2013 Apr;123(4):1662-76. doi: 10.1172/JCI65538. Epub 2013 Mar 15.

2.

Nervous glucose sensing regulates postnatal β cell proliferation and glucose homeostasis.

Tarussio D, Metref S, Seyer P, Mounien L, Vallois D, Magnan C, Foretz M, Thorens B.

J Clin Invest. 2014 Jan;124(1):413-24. doi: 10.1172/JCI69154. Epub 2013 Dec 16.

3.

Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice.

Choi D, Cai EP, Schroer SA, Wang L, Woo M.

Lab Invest. 2011 Apr;91(4):527-38. doi: 10.1038/labinvest.2010.207. Epub 2011 Jan 17.

4.

The bile acid sensor FXR regulates insulin transcription and secretion.

Renga B, Mencarelli A, Vavassori P, Brancaleone V, Fiorucci S.

Biochim Biophys Acta. 2010 Mar;1802(3):363-72. doi: 10.1016/j.bbadis.2010.01.002. Epub 2010 Jan 7.

5.

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism.

Herman MA, Peroni OD, Villoria J, Schön MR, Abumrad NA, Blüher M, Klein S, Kahn BB.

Nature. 2012 Apr 19;484(7394):333-8. doi: 10.1038/nature10986.

6.

Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells.

Trabelsi MS, Daoudi M, Prawitt J, Ducastel S, Touche V, Sayin SI, Perino A, Brighton CA, Sebti Y, Kluza J, Briand O, Dehondt H, Vallez E, Dorchies E, Baud G, Spinelli V, Hennuyer N, Caron S, Bantubungi K, Caiazzo R, Reimann F, Marchetti P, Lefebvre P, Bäckhed F, Gribble FM, Schoonjans K, Pattou F, Tailleux A, Staels B, Lestavel S.

Nat Commun. 2015 Jul 2;6:7629. doi: 10.1038/ncomms8629.

7.

Novel role for SGK3 in glucose homeostasis revealed in SGK3/Akt2 double-null mice.

Yao LJ, McCormick JA, Wang J, Yang KY, Kidwai A, Colussi GL, Boini KM, Birnbaum MJ, Lang F, German MS, Pearce D.

Mol Endocrinol. 2011 Dec;25(12):2106-18. doi: 10.1210/me.2010-0329. Epub 2011 Oct 6.

8.

The nucleosome binding protein HMGN3 modulates the transcription profile of pancreatic beta cells and affects insulin secretion.

Ueda T, Furusawa T, Kurahashi T, Tessarollo L, Bustin M.

Mol Cell Biol. 2009 Oct;29(19):5264-76. doi: 10.1128/MCB.00526-09. Epub 2009 Aug 3.

9.

Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.

Beall C, Piipari K, Al-Qassab H, Smith MA, Parker N, Carling D, Viollet B, Withers DJ, Ashford ML.

Biochem J. 2010 Jul 15;429(2):323-33. doi: 10.1042/BJ20100231.

10.

Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism.

Vetterli L, Brun T, Giovannoni L, Bosco D, Maechler P.

J Biol Chem. 2011 Feb 25;286(8):6049-60. doi: 10.1074/jbc.M110.176842. Epub 2010 Dec 16.

11.

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression.

Dentin R, Pégorier JP, Benhamed F, Foufelle F, Ferré P, Fauveau V, Magnuson MA, Girard J, Postic C.

J Biol Chem. 2004 May 7;279(19):20314-26. Epub 2004 Feb 25.

12.

Hepatic ABCA1 expression improves β-cell function and glucose tolerance.

de Haan W, Karasinska JM, Ruddle P, Hayden MR.

Diabetes. 2014 Dec;63(12):4076-82. doi: 10.2337/db14-0548. Epub 2014 Jul 15.

13.

Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

Dentin R, Benhamed F, Hainault I, Fauveau V, Foufelle F, Dyck JR, Girard J, Postic C.

Diabetes. 2006 Aug;55(8):2159-70.

14.

Farnesoid X receptor is essential for normal glucose homeostasis.

Ma K, Saha PK, Chan L, Moore DD.

J Clin Invest. 2006 Apr;116(4):1102-9. Epub 2006 Mar 23.

15.

Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1.

Grefhorst A, Schreurs M, Oosterveer MH, Cortés VA, Havinga R, Herling AW, Reijngoud DJ, Groen AK, Kuipers F.

Biochem J. 2010 Dec 1;432(2):249-54. doi: 10.1042/BJ20101225.

PMID:
20854262
16.

The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.

Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk TH, Grefhorst A, Abdelkarim M, Caron S, Torpier G, Fruchart JC, Gonzalez FJ, Kuipers F, Staels B.

J Biol Chem. 2006 Apr 21;281(16):11039-49. Epub 2006 Jan 30.

17.

Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice.

Zhang Y, Lee FY, Barrera G, Lee H, Vales C, Gonzalez FJ, Willson TM, Edwards PA.

Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):1006-11. Epub 2006 Jan 12.

18.

Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment.

Brunham LR, Kruit JK, Pape TD, Timmins JM, Reuwer AQ, Vasanji Z, Marsh BJ, Rodrigues B, Johnson JD, Parks JS, Verchere CB, Hayden MR.

Nat Med. 2007 Mar;13(3):340-7. Epub 2007 Feb 18.

PMID:
17322896
19.

The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling.

He Y, Gong L, Fang Y, Zhan Q, Liu HX, Lu Y, Guo GL, Lehman-McKeeman L, Fang J, Wan YJ.

BMC Genomics. 2013 Aug 28;14:575. doi: 10.1186/1471-2164-14-575.

20.

GTPase ARFRP1 is essential for normal hepatic glycogen storage and insulin-like growth factor 1 secretion.

Hesse D, Jaschke A, Kanzleiter T, Witte N, Augustin R, Hommel A, Püschel GP, Petzke KJ, Joost HG, Schupp M, Schürmann A.

Mol Cell Biol. 2012 Nov;32(21):4363-74. doi: 10.1128/MCB.00522-12. Epub 2012 Aug 27.

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