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Items: 1 to 20 of 111

1.

Unequivocal role of pyrazine ring in medicinally important compounds: a review.

Miniyar PB, Murumkar PR, Patil PS, Barmade MA, Bothara KG.

Mini Rev Med Chem. 2013 Oct;13(11):1607-25. Review.

PMID:
23544468
2.

Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells.

Bouloc N, Large JM, Kosmopoulou M, Sun C, Faisal A, Matteucci M, Reynisson J, Brown N, Atrash B, Blagg J, McDonald E, Linardopoulos S, Bayliss R, Bavetsias V.

Bioorg Med Chem Lett. 2010 Oct 15;20(20):5988-93. doi: 10.1016/j.bmcl.2010.08.091. Epub 2010 Aug 21.

PMID:
20833547
3.

Antimycobacterial activity of substituted isosteres of pyridine- and pyrazinecarboxylic acids. 2.

Gezginci MH, Martin AR, Franzblau SG.

J Med Chem. 2001 May 10;44(10):1560-3.

PMID:
11334565
4.

Substituted N-Phenylpyrazine-2-carboxamides: synthesis and antimycobacterial evaluation.

Dolezal M, Zitko J, Kesetovicová D, Kunes J, Svobodová M.

Molecules. 2009 Oct 20;14(10):4180-9. doi: 10.3390/molecules14104180.

5.

Synthesis and antimycobacterial evaluation of N'-(E)-heteroaromaticpyrazine-2-carbohydrazide derivatives.

Lima CH, Henriques MG, Candéa AL, Lourenço MC, Bezerra FA, Ferreira ML, Kaiser CR, de Souza MV.

Med Chem. 2011 May;7(3):245-9. doi: 1573-4064/11 $58.00+.00.

PMID:
21486206
6.
7.

Studies on pyrazine derivatives. XXXII. Synthesis and tuberculostatic activity of acetylpyrazine thiosemicarbazone derivatives.

Milczarska B, Foks H, Trapkowski Z, Milzyńska-Kołaczek A, Janowiec M, Zwolska Z, Andrzejczyk Z.

Acta Pol Pharm. 1998 Jul-Aug;55(4):289-95.

8.

Studies on pyrazine derivatives, XXIX: Synthesis of N1-thioamido substituted pyrazincarboxyamidrazones with expected tuberculostatic activity.

Orlewska C, Foks H, Janowiec M, Zwolskakwiek Z.

Pharmazie. 1995 Aug;50(8):565-6. No abstract available.

PMID:
7568322
9.

N1-Hetaryl substituted pyridine- and pyrazinecarboxamidrazones with antimycobacterial activity.

Ranft D, Lehwark-Yvetot G, Schaper KJ, Büge A.

Arch Pharm (Weinheim). 1997 Jun;330(6):169-72.

PMID:
9297448
10.
11.

Studies on pyrazine derivatives--XXXIV. Synthesis and tuberculostatic activity of alpha-oxo ketene dithioacetals pyrazine derivatives.

Milczarska B, Foks H, Mikołajczyk K, Janowiec M, Zwolska Z, Andrzejczyk Z.

Acta Pol Pharm. 2000 Jul-Aug;57(4):307-10.

12.

[Studies of pyrazine derivatives. XX. Synthesis and tuberculostatic activity of 3-pyrazinol-1,2,4-oxadiazole derivatives].

Pancechowska-Ksepko D, Foks H, Janowiec M, Zwolska-Kwiek Z.

Acta Pol Pharm. 1986;43(3):211-7. Polish. No abstract available.

PMID:
3098054
13.

Synthesis and biological evaluation of new 3-(6-hydroxyindol-2-yl)-5-(Phenyl) pyridine or pyrazine V-Shaped molecules as kinase inhibitors and cytotoxic agents.

Kassis P, Brzeszcz J, Bénéteau V, Lozach O, Meijer L, Le Guével R, Guillouzo C, Lewiński K, Bourg S, Colliandre L, Routier S, Mérour JY.

Eur J Med Chem. 2011 Nov;46(11):5416-34. doi: 10.1016/j.ejmech.2011.08.048. Epub 2011 Sep 8.

PMID:
21944287
14.

[Studies on pyrazine derivatives. XIX. Synthesis and tuberculostatic activity of various 3-phenoxy-2-pyrazinecarboxylic acid derivatives].

Pancechowska-Ksepko D, Foks H, Janowiec M.

Acta Pol Pharm. 1983;40(1):15-9. Polish. No abstract available.

PMID:
6410689
15.

[Studies of pyrazine derivatives. XVII. Synthesis and the tuberculostatic activity of pyrazinyl-1,3,4-oxadiazole derivatives].

Pancechowska-Ksepko D, Foks H, Landowska E, Janowiec M, Zwolska-Kwiek Z.

Acta Pol Pharm. 1986;43(2):116-23. Polish. No abstract available.

PMID:
3096080
16.

Synthesis and structure-activity relationships of 1,2,3,4-tetrahydropyrido[2,3-b]pyrazines as potent and selective inhibitors of the anaplastic lymphoma kinase.

Milkiewicz KL, Weinberg LR, Albom MS, Angeles TS, Cheng M, Ghose AK, Roemmele RC, Theroff JP, Underiner TL, Zificsak CA, Dorsey BD.

Bioorg Med Chem. 2010 Jun 15;18(12):4351-62. doi: 10.1016/j.bmc.2010.04.087. Epub 2010 Apr 29.

PMID:
20483621
17.

[Synthesis and tuberculostatic activity of some derivatives of pyrazine-2-carboxylic acid].

Foks H, Manowska W, Sienicka J.

Acta Pol Pharm. 1976;33(6):687-93. Polish. No abstract available.

PMID:
827924
18.

[Studies on pyrazine derivatives. XXII. Synthesis and tuberculostatic activity of the products of reactions of pyrazinyl-1,3,4-oxadiazol-2-thione with amines].

Pancechowska-Ksepko D, Foks H, Janowiec M, Zwolska-Kwiek Z.

Acta Pol Pharm. 1988;45(3):193-200. Polish. No abstract available.

PMID:
3149138
19.

Studies on pyrazine derivatives. XXXIII. Synthesis and tuberculostatic activity of 1-[1-(2-pyrazinyl)-ethyl]-4-N-substituted thiosemicarbazide derivatives.

Milczarska B, Foks H, Sokołowska J, Janowiec M, Zwolska Z, Andrzejczyk Z.

Acta Pol Pharm. 1999 Mar-Apr;56(2):121-6.

20.

Synthesis and docking studies of pyrazine-thiazolidinone hybrid scaffold targeting dormant tuberculosis.

Chitre TS, Asgaonkar KD, Miniyar PB, Dharme AB, Arkile MA, Yeware A, Sarkar D, Khedkar VM, Jha PC.

Bioorg Med Chem Lett. 2016 May 1;26(9):2224-8. doi: 10.1016/j.bmcl.2016.03.055. Epub 2016 Mar 15.

PMID:
27017114

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