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Items: 1 to 20 of 237

1.

Design-based re-engineering of biosynthetic gene clusters: plug-and-play in practice.

Frasch HJ, Medema MH, Takano E, Breitling R.

Curr Opin Biotechnol. 2013 Dec;24(6):1144-50. doi: 10.1016/j.copbio.2013.03.006. Epub 2013 Mar 27. Review.

PMID:
23540422
2.

Recent advances in the heterologous expression of microbial natural product biosynthetic pathways.

Ongley SE, Bian X, Neilan BA, Müller R.

Nat Prod Rep. 2013 Aug;30(8):1121-38. doi: 10.1039/c3np70034h. Epub 2013 Jul 5. Review.

PMID:
23832108
3.

Mining microbial genomes for new natural products and biosynthetic pathways.

Challis GL.

Microbiology. 2008 Jun;154(Pt 6):1555-69. doi: 10.1099/mic.0.2008/018523-0.

PMID:
18524911
4.

DNA assembler: a synthetic biology tool for characterizing and engineering natural product gene clusters.

Shao Z, Zhao H.

Methods Enzymol. 2012;517:203-24. doi: 10.1016/B978-0-12-404634-4.00010-3.

5.

Synthetic Biology Approaches to New Bisindoles.

Alkhalaf LM, Du YL, Ryan KS.

Methods Enzymol. 2016;575:21-37. doi: 10.1016/bs.mie.2016.02.017. Epub 2016 Mar 24.

PMID:
27417923
6.

Bioengineering natural product biosynthetic pathways for therapeutic applications.

Wu MC, Law B, Wilkinson B, Micklefield J.

Curr Opin Biotechnol. 2012 Dec;23(6):931-40. doi: 10.1016/j.copbio.2012.03.008. Epub 2012 Apr 7. Review.

PMID:
22487048
7.

Computational strategies for genome-based natural product discovery and engineering in fungi.

van der Lee TAJ, Medema MH.

Fungal Genet Biol. 2016 Apr;89:29-36. doi: 10.1016/j.fgb.2016.01.006. Epub 2016 Jan 13. Review.

8.

Computational genomic identification and functional reconstitution of plant natural product biosynthetic pathways.

Medema MH, Osbourn A.

Nat Prod Rep. 2016 Aug 27;33(8):951-62. doi: 10.1039/c6np00035e. Epub 2016 Jun 20. Review.

9.

Actinomycetes biosynthetic potential: how to bridge in silico and in vivo?

Rebets Y, Brötz E, Tokovenko B, Luzhetskyy A.

J Ind Microbiol Biotechnol. 2014 Feb;41(2):387-402. doi: 10.1007/s10295-013-1352-9. Epub 2013 Oct 15. Review.

PMID:
24127068
10.

Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters.

Ikeda H, Kazuo SY, Omura S.

J Ind Microbiol Biotechnol. 2014 Feb;41(2):233-50. doi: 10.1007/s10295-013-1327-x. Epub 2013 Aug 29. Review.

PMID:
23990133
11.

Yeast homologous recombination-based promoter engineering for the activation of silent natural product biosynthetic gene clusters.

Montiel D, Kang HS, Chang FY, Charlop-Powers Z, Brady SF.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):8953-8. doi: 10.1073/pnas.1507606112. Epub 2015 Jul 6.

12.

Genome-based bioprospecting of microbes for new therapeutics.

Zotchev SB, Sekurova ON, Katz L.

Curr Opin Biotechnol. 2012 Dec;23(6):941-7. doi: 10.1016/j.copbio.2012.04.002. Epub 2012 May 3. Review.

PMID:
22560158
13.

Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery.

Rudolf JD, Yan X, Shen B.

J Ind Microbiol Biotechnol. 2016 Mar;43(2-3):261-76. doi: 10.1007/s10295-015-1671-0. Epub 2015 Aug 29.

14.

Synthetic genomics: potential and limitations.

Montague MG, Lartigue C, Vashee S.

Curr Opin Biotechnol. 2012 Oct;23(5):659-65. doi: 10.1016/j.copbio.2012.01.014. Epub 2012 Feb 17. Review.

PMID:
22342755
15.

Gene clustering in plant specialized metabolism.

Nützmann HW, Osbourn A.

Curr Opin Biotechnol. 2014 Apr;26:91-9. doi: 10.1016/j.copbio.2013.10.009. Epub 2013 Nov 16. Review. Erratum in: Curr Opin Biotechnol. 2014 Apr;26:199.

16.

Synthetic biology triggers new era of antibiotics development.

Wang J, Xiong Z, Meng H, Wang Y, Wang Y.

Subcell Biochem. 2012;64:95-114. doi: 10.1007/978-94-007-5055-5_5. Review.

PMID:
23080247
17.

Identification and activation of novel biosynthetic gene clusters by genome mining in the kirromycin producer Streptomyces collinus Tü 365.

Iftime D, Kulik A, Härtner T, Rohrer S, Niedermeyer TH, Stegmann E, Weber T, Wohlleben W.

J Ind Microbiol Biotechnol. 2016 Mar;43(2-3):277-91. doi: 10.1007/s10295-015-1685-7. Epub 2015 Oct 3.

PMID:
26433383
18.

Native and engineered promoters in natural product discovery.

Myronovskyi M, Luzhetskyy A.

Nat Prod Rep. 2016 Aug 27;33(8):1006-19. doi: 10.1039/c6np00002a. Epub 2016 Jul 20. Review.

PMID:
27438486
19.

Meta-omic characterization of prokaryotic gene clusters for natural product biosynthesis.

Schofield MM, Sherman DH.

Curr Opin Biotechnol. 2013 Dec;24(6):1151-8. doi: 10.1016/j.copbio.2013.05.001. Epub 2013 May 31. Review.

20.

Natural products - modifying metabolite pathways in plants.

Staniek A, Bouwmeester H, Fraser PD, Kayser O, Martens S, Tissier A, van der Krol S, Wessjohann L, Warzecha H.

Biotechnol J. 2013 Oct;8(10):1159-71. doi: 10.1002/biot.201300224. Epub 2013 Sep 17. Review.

PMID:
24092673

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