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Items: 1 to 20 of 225

1.

An approach for integrating toxicogenomic data in risk assessment: the dibutyl phthalate case study.

Euling SY, Thompson CM, Chiu WA, Benson R.

Toxicol Appl Pharmacol. 2013 Sep 15;271(3):324-35. doi: 10.1016/j.taap.2013.03.013. Epub 2013 Mar 26.

PMID:
23537663
2.

Use of genomic data in risk assessment case study: II. Evaluation of the dibutyl phthalate toxicogenomic data set.

Euling SY, White LD, Kim AS, Sen B, Wilson VS, Keshava C, Keshava N, Hester S, Ovacik MA, Ierapetritou MG, Androulakis IP, Gaido KW.

Toxicol Appl Pharmacol. 2013 Sep 15;271(3):349-62. doi: 10.1016/j.taap.2011.06.014. Epub 2011 Jun 30.

PMID:
21745491
3.

Use of genomic data in risk assessment case study: I. Evaluation of the dibutyl phthalate male reproductive development toxicity data set.

Makris SL, Euling SY, Gray LE Jr, Benson R, Foster P.

Toxicol Appl Pharmacol. 2013 Sep 15;271(3):336-48. doi: 10.1016/j.taap.2010.09.006. Epub 2010 Sep 16.

PMID:
20849870
4.

Use of comparative genomics approaches to characterize interspecies differences in response to environmental chemicals: challenges, opportunities, and research needs.

Burgess-Herbert SL, Euling SY.

Toxicol Appl Pharmacol. 2013 Sep 15;271(3):372-85. doi: 10.1016/j.taap.2011.11.011. Epub 2011 Nov 28. Review.

PMID:
22142766
5.

Pathway modeling of microarray data: a case study of pathway activity changes in the testis following in utero exposure to dibutyl phthalate (DBP).

Ovacik MA, Sen B, Euling SY, Gaido KW, Ierapetritou MG, Androulakis IP.

Toxicol Appl Pharmacol. 2013 Sep 15;271(3):386-94. doi: 10.1016/j.taap.2010.09.008. Epub 2010 Sep 17.

PMID:
20850466
6.

Identification of differentially expressed genes in the testis of Sprague-Dawley rats treated with di(n-butyl) phthalate.

Ryu JY, Lee BM, Kacew S, Kim HS.

Toxicology. 2007 May 5;234(1-2):103-12. Epub 2007 Feb 17.

PMID:
17379376
7.

Time-response effects of testicular gene expression profiles in Sprague-Dawley male rats treated with di(n-butyl) phthalate.

Ryu JY, Lee E, Kim TH, Lee YJ, Lee J, Lee BM, Kwack SJ, Jung KK, Han SY, Kim SH, Kacew S, Kim HS.

J Toxicol Environ Health A. 2008;71(23):1542-9. doi: 10.1080/15287390802391992.

PMID:
18923996
8.

Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate.

Barlow NJ, Phillips SL, Wallace DG, Sar M, Gaido KW, Foster PM.

Toxicol Sci. 2003 Jun;73(2):431-41. Epub 2003 Apr 15.

PMID:
12700402
9.

Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genes.

Howdeshell KL, Furr J, Lambright CR, Rider CV, Wilson VS, Gray LE Jr.

Toxicol Sci. 2007 Sep;99(1):190-202. Epub 2007 Mar 30.

PMID:
17400582
10.

Integrating mechanistic and polymorphism data to characterize human genetic susceptibility for environmental chemical risk assessment in the 21st century.

Mortensen HM, Euling SY.

Toxicol Appl Pharmacol. 2013 Sep 15;271(3):395-404. doi: 10.1016/j.taap.2011.01.015. Epub 2011 Feb 1.

PMID:
21291902
11.

Reproductive toxicity and pharmacokinetics of di-n-butyl phthalate (DBP) following dietary exposure of pregnant rats.

Struve MF, Gaido KW, Hensley JB, Lehmann KP, Ross SM, Sochaski MA, Willson GA, Dorman DC.

Birth Defects Res B Dev Reprod Toxicol. 2009 Aug;86(4):345-54. doi: 10.1002/bdrb.20199.

PMID:
19585553
12.

Effects of di(n-butyl) and monobutyl phthalate on steroidogenesis pathways in the murine Leydig tumor cell line MLTC-1.

Chen X, Zhou QH, Leng L, Chen X, Sun ZR, Tang NJ.

Environ Toxicol Pharmacol. 2013 Sep;36(2):332-8. doi: 10.1016/j.etap.2013.04.013. Epub 2013 May 6.

PMID:
23712133
13.

Derivation of Biomonitoring Equivalents for di-n-butyl phthalate (DBP), benzylbutyl phthalate (BzBP), and diethyl phthalate (DEP).

Aylward LL, Hays SM, Gagné M, Krishnan K.

Regul Toxicol Pharmacol. 2009 Dec;55(3):259-67. doi: 10.1016/j.yrtph.2009.09.003. Epub 2009 Sep 12.

PMID:
19751787
14.

The effects on steroidogenesis and histopathology of adult male Japanese quails (Coturnix coturnix japonica) testis following pre-pubertal exposure to di(n-butyl) phthalate (DBP).

Bello UM, Madekurozwa MC, Groenewald HB, Aire TA, Arukwe A.

Comp Biochem Physiol C Toxicol Pharmacol. 2014 Nov;166:24-33. doi: 10.1016/j.cbpc.2014.06.005. Epub 2014 Jun 28.

PMID:
24983780
16.

Mapping gene expression changes in the fetal rat testis following acute dibutyl phthalate exposure defines a complex temporal cascade of responding cell types.

Johnson KJ, Hensley JB, Kelso MD, Wallace DG, Gaido KW.

Biol Reprod. 2007 Dec;77(6):978-89. Epub 2007 Sep 19.

PMID:
17881770
17.

Low concentrations mono-butyl phthalate stimulates steroidogenesis by facilitating steroidogenic acute regulatory protein expression in mouse Leydig tumor cells (MLTC-1).

Wang Y, Song L, Hong X, Cui L, Zhang Z, Xiao H, Zhou J, Wang X.

Chem Biol Interact. 2006 Dec 1;164(1-2):15-24. Epub 2006 Sep 1.

PMID:
16999944
18.

Differential steroidogenic gene expression in the fetal adrenal gland versus the testis and rapid and dynamic response of the fetal testis to di(n-butyl) phthalate.

Thompson CJ, Ross SM, Hensley J, Liu K, Heinze SC, Young SS, Gaido KW.

Biol Reprod. 2005 Nov;73(5):908-17. Epub 2005 Jun 29.

PMID:
15987825
19.

Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis.

Wilson VS, Lambright C, Furr J, Ostby J, Wood C, Held G, Gray LE Jr.

Toxicol Lett. 2004 Feb 2;146(3):207-15.

PMID:
14687758
20.

Di (n-butyl) phthalate inhibits testosterone synthesis through a glucocorticoid-mediated pathway in rats.

Xiao-feng Z, Nai-qiang Q, Jing Z, Zi L, Yang Z.

Int J Toxicol. 2009 Sep-Oct;28(5):448-56. doi: 10.1177/1091581809342596.

PMID:
19815848

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