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Trop-2 promotes prostate cancer metastasis by modulating β(1) integrin functions.

Trerotola M, Jernigan DL, Liu Q, Siddiqui J, Fatatis A, Languino LR.

Cancer Res. 2013 May 15;73(10):3155-67. doi: 10.1158/0008-5472.CAN-12-3266. Epub 2013 Mar 27.


Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axis.

Trerotola M, Li J, Alberti S, Languino LR.

J Cell Physiol. 2012 Nov;227(11):3670-7. doi: 10.1002/jcp.24074.


Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts.

Trerotola M, Ganguly KK, Fazli L, Fedele C, Lu H, Dutta A, Liu Q, De Angelis T, Riddell LW, Riobo NA, Gleave ME, Zoubeidi A, Pestell RG, Altieri DC, Languino LR.

Oncotarget. 2015 Jun 10;6(16):14318-28. Erratum in: Oncotarget. 2015 Oct 20;6(32):34038.


Prostatic carcinoma cell migration via alpha(v)beta3 integrin is modulated by a focal adhesion kinase pathway.

Zheng DQ, Woodard AS, Fornaro M, Tallini G, Languino LR.

Cancer Res. 1999 Apr 1;59(7):1655-64.


In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signaling.

Casar B, Rimann I, Kato H, Shattil SJ, Quigley JP, Deryugina EI.

Oncogene. 2014 Jan 9;33(2):255-68. doi: 10.1038/onc.2012.547. Epub 2012 Dec 3.


The role of alpha(v)beta(3) in prostate cancer progression.

Cooper CR, Chay CH, Pienta KJ.

Neoplasia. 2002 May-Jun;4(3):191-4. Review.


Talin1 phosphorylation activates β1 integrins: a novel mechanism to promote prostate cancer bone metastasis.

Jin JK, Tien PC, Cheng CJ, Song JH, Huang C, Lin SH, Gallick GE.

Oncogene. 2015 Apr 2;34(14):1811-21. doi: 10.1038/onc.2014.116. Epub 2014 May 5.


Targeting constitutively activated β1 integrins inhibits prostate cancer metastasis.

Lee YC, Jin JK, Cheng CJ, Huang CF, Song JH, Huang M, Brown WS, Zhang S, Yu-Lee LY, Yeh ET, McIntyre BW, Logothetis CJ, Gallick GE, Lin SH.

Mol Cancer Res. 2013 Apr;11(4):405-17. doi: 10.1158/1541-7786.MCR-12-0551. Epub 2013 Jan 21.


Nectin-like molecule-5/Tage4 enhances cell migration in an integrin-dependent, Nectin-3-independent manner.

Ikeda W, Kakunaga S, Takekuni K, Shingai T, Satoh K, Morimoto K, Takeuchi M, Imai T, Takai Y.

J Biol Chem. 2004 Apr 23;279(17):18015-25. Epub 2004 Feb 9.


Involvement of tumor cell integrin alpha v beta 3 in hematogenous metastasis of human melanoma cells.

Felding-Habermann B, Fransvea E, O'Toole TE, Manzuk L, Faha B, Hensler M.

Clin Exp Metastasis. 2002;19(5):427-36.


Inositol hexaphosphate (IP6) inhibits key events of cancer metastasis: II. Effects on integrins and focal adhesions.

Tantivejkul K, Vucenik I, Shamsuddin AM.

Anticancer Res. 2003 Sep-Oct;23(5A):3681-9.


Cell adhesion and tumor metastasis.

Ruoslahti E.

Princess Takamatsu Symp. 1994;24:99-105. Review.


Metastasis suppressor KAI1/CD82 attenuates the matrix adhesion of human prostate cancer cells by suppressing fibronectin expression and β1 integrin activation.

Lee HA, Park I, Byun HJ, Jeoung D, Kim YM, Lee H.

Cell Physiol Biochem. 2011;27(5):575-86. doi: 10.1159/000329979. Epub 2011 Jun 15.


The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged.

Ding Q, Stewart J Jr, Olman MA, Klobe MR, Gladson CL.

J Biol Chem. 2003 Oct 10;278(41):39882-91. Epub 2003 Jul 24.


Talin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance.

Sakamoto S, McCann RO, Dhir R, Kyprianou N.

Cancer Res. 2010 Mar 1;70(5):1885-95. doi: 10.1158/0008-5472.CAN-09-2833. Epub 2010 Feb 16.


Angiotensin II enhances integrin and alpha-actinin expression in adult rat cardiac fibroblasts.

Kawano H, Cody RJ, Graf K, Goetze S, Kawano Y, Schnee J, Law RE, Hsueh WA.

Hypertension. 2000 Jan;35(1 Pt 2):273-9.


Androgen-induced cell migration: role of androgen receptor/filamin A association.

Castoria G, D'Amato L, Ciociola A, Giovannelli P, Giraldi T, Sepe L, Paolella G, Barone MV, Migliaccio A, Auricchio F.

PLoS One. 2011 Feb 16;6(2):e17218. doi: 10.1371/journal.pone.0017218.


Focal adhesion kinase (FAK) phosphorylation is not required for genistein-induced FAK-beta-1-integrin complex formation.

Liu Y, Kyle E, Lieberman R, Crowell J, Kellof G, Bergan RC.

Clin Exp Metastasis. 2000;18(3):203-12.


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