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Items: 1 to 20 of 152

1.

Potentiation of GABAA receptor activity by volatile anaesthetics is reduced by α5GABAA receptor-preferring inverse agonists.

Lecker I, Yin Y, Wang DS, Orser BA.

Br J Anaesth. 2013 Jun;110 Suppl 1:i73-81. doi: 10.1093/bja/aet038. Epub 2013 Mar 27.

3.

Inhibition of α5 γ-Aminobutyric acid type A receptors restores recognition memory after general anesthesia.

Zurek AA, Bridgwater EM, Orser BA.

Anesth Analg. 2012 Apr;114(4):845-55. doi: 10.1213/ANE.0b013e31824720da. Epub 2012 Mar 1.

PMID:
22383672
4.

In vitro and in vivo properties of 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA receptor alpha5 subtype-selective inverse agonist.

Atack JR, Maubach KA, Wafford KA, O'Connor D, Rodrigues AD, Evans DC, Tattersall FD, Chambers MS, MacLeod AM, Eng WS, Ryan C, Hostetler E, Sanabria SM, Gibson RE, Krause S, Burns HD, Hargreaves RJ, Agrawal NG, McKernan RM, Murphy MG, Gingrich K, Dawson GR, Musson DG, Petty KJ.

J Pharmacol Exp Ther. 2009 Nov;331(2):470-84. doi: 10.1124/jpet.109.157636. Epub 2009 Aug 24.

5.

Effects of isoflurane on gamma-aminobutyric acid type A receptors activated by full and partial agonists.

Topf N, Jenkins A, Baron N, Harrison NL.

Anesthesiology. 2003 Feb;98(2):306-11. Erratum in: Anesthesiology. 2003 Mar;98(3):803.

PMID:
12552186
6.

Volatile anesthetic effects on isolated GABA synapses and extrasynaptic receptors.

Ogawa SK, Tanaka E, Shin MC, Kotani N, Akaike N.

Neuropharmacology. 2011 Mar;60(4):701-10. doi: 10.1016/j.neuropharm.2010.11.016. Epub 2010 Nov 25.

PMID:
21111749
7.

Selective enhancement of tonic GABAergic inhibition in murine hippocampal neurons by low concentrations of the volatile anesthetic isoflurane.

Caraiscos VB, Newell JG, You-Ten KE, Elliott EM, Rosahl TW, Wafford KA, MacDonald JF, Orser BA.

J Neurosci. 2004 Sep 29;24(39):8454-8.

8.

Alpha5GABAA receptors regulate the intrinsic excitability of mouse hippocampal pyramidal neurons.

Bonin RP, Martin LJ, MacDonald JF, Orser BA.

J Neurophysiol. 2007 Oct;98(4):2244-54. Epub 2007 Aug 22.

9.

GABAergic excitotoxicity injury of the immature hippocampal pyramidal neurons' exposure to isoflurane.

Zhao YL, Xiang Q, Shi QY, Li SY, Tan L, Wang JT, Jin XG, Luo AL.

Anesth Analg. 2011 Nov;113(5):1152-60. doi: 10.1213/ANE.0b013e318230b3fd. Epub 2011 Sep 14.

PMID:
21918167
10.

Short-term memory impairment after isoflurane in mice is prevented by the α5 γ-aminobutyric acid type A receptor inverse agonist L-655,708.

Saab BJ, Maclean AJ, Kanisek M, Zurek AA, Martin LJ, Roder JC, Orser BA.

Anesthesiology. 2010 Nov;113(5):1061-71. doi: 10.1097/ALN.0b013e3181f56228.

PMID:
20966663
11.

GABA(A) receptor activation and open-channel block by volatile anaesthetics: a new principle of receptor modulation?

Haseneder R, Rammes G, Zieglgänsberger W, Kochs E, Hapfelmeier G.

Eur J Pharmacol. 2002 Sep 6;451(1):43-50.

PMID:
12223227
12.

Isoflurane regulates atypical type-A γ-aminobutyric acid receptors in alveolar type II epithelial cells.

Xiang YY, Chen X, Li J, Wang S, Faclier G, Macdonald JF, Hogg JC, Orser BA, Lu WY.

Anesthesiology. 2013 May;118(5):1065-75. doi: 10.1097/ALN.0b013e31828e180e.

PMID:
23485993
13.

Sevoflurane modulates both GABAA and GABAB receptors in area CA1 of rat hippocampus.

Hirota K, Roth SH.

Br J Anaesth. 1997 Jan;78(1):60-5.

PMID:
9059206
15.

Isoflurane and sevoflurane dose-dependently impair hippocampal long-term potentiation.

Haseneder R, Kratzer S, von Meyer L, Eder M, Kochs E, Rammes G.

Eur J Pharmacol. 2009 Nov 25;623(1-3):47-51. doi: 10.1016/j.ejphar.2009.09.022. Epub 2009 Sep 16.

PMID:
19765574
17.

Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane.

Liao M, Sonner JM, Jurd R, Rudolph U, Borghese CM, Harris RA, Laster MJ, Eger EI 2nd.

Anesth Analg. 2005 Aug;101(2):412-8, table of contents.

PMID:
16037154
18.

Effects of the volatile anesthetic sevoflurane on tonic GABA currents in the mouse striatum during postnatal development.

Ando N, Sugasawa Y, Inoue R, Aosaki T, Miura M, Nishimura K.

Eur J Neurosci. 2014 Oct;40(8):3147-57. doi: 10.1111/ejn.12691. Epub 2014 Aug 19.

PMID:
25139222
19.

Inflammation Increases Neuronal Sensitivity to General Anesthetics.

Avramescu S, Wang DS, Lecker I, To WT, Penna A, Whissell PD, Mesbah-Oskui L, Horner RL, Orser BA.

Anesthesiology. 2016 Feb;124(2):417-27. doi: 10.1097/ALN.0000000000000943.

PMID:
26566283
20.

The interaction of noradrenaline with sevoflurane on GABA(A) receptor-mediated inhibitory postsynaptic currents in the rat hippocampus.

Nishikawa K, Kubo K, Ishizeki J, Takazawa T, Saito S, Goto F.

Brain Res. 2005 Mar 28;1039(1-2):153-61.

PMID:
15781057

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