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TLR2 down-regulates FcεRI and its transcription factor PU.1 in human Langerhans cells.

Herrmann N, Koch S, Leib N, Bedorf J, Wilms H, Schnautz S, Fimmers R, Bieber T.

Allergy. 2013;68(5):621-8. doi: 10.1111/all.12145. Epub 2013 Mar 27.


Critical Roles for PU.1, GATA1, and GATA2 in the expression of human FcεRI on mast cells: PU.1 and GATA1 transactivate FCER1A, and GATA2 transactivates FCER1A and MS4A2.

Inage E, Kasakura K, Yashiro T, Suzuki R, Baba Y, Nakano N, Hara M, Tanabe A, Oboki K, Matsumoto K, Saito H, Niyonsaba F, Ohtsuka Y, Ogawa H, Okumura K, Shimizu T, Nishiyama C.

J Immunol. 2014 Apr 15;192(8):3936-46. doi: 10.4049/jimmunol.1302366. Epub 2014 Mar 17.


Toll-like receptor 2 agonist Pam3CSK4 up-regulates FcεRI receptor expression on monocytes from patients with severe extrinsic atopic dermatitis.

Song Z, Deng X, Chen W, Xu J, Chen S, Zhong H, Hao F.

J Eur Acad Dermatol Venereol. 2015 Nov;29(11):2169-76. doi: 10.1111/jdv.13172. Epub 2015 Apr 24.


Suppressive effect of Elf-1 on FcepsilonRI alpha-chain expression in primary mast cells.

Wang QH, Nishiyama C, Nakano N, Shimokawa N, Hara M, Kanada S, Ogawa H, Okumura K.

Immunogenetics. 2008 Oct;60(10):557-63. doi: 10.1007/s00251-008-0318-y. Epub 2008 Jul 16.


Toll-like receptor alterations in myelodysplastic syndrome.

Wei Y, Dimicoli S, Bueso-Ramos C, Chen R, Yang H, Neuberg D, Pierce S, Jia Y, Zheng H, Wang H, Wang X, Nguyen M, Wang SA, Ebert B, Bejar R, Levine R, Abdel-Wahab O, Kleppe M, Ganan-Gomez I, Kantarjian H, Garcia-Manero G.

Leukemia. 2013 Sep;27(9):1832-40. doi: 10.1038/leu.2013.180. Epub 2013 Jun 14.


Expression of toll-like receptor 2, NOD2 and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes.

Kobayashi M, Yoshiki R, Sakabe J, Kabashima K, Nakamura M, Tokura Y.

Br J Dermatol. 2009 Feb;160(2):297-304. doi: 10.1111/j.1365-2133.2008.08897.x. Epub 2008 Oct 21.


Expression profiles and function of Toll-like receptors 2 and 4 in peripheral blood mononuclear cells of chronic hepatitis B patients.

Chen Z, Cheng Y, Xu Y, Liao J, Zhang X, Hu Y, Zhang Q, Wang J, Zhang Z, Shen F, Yuan Z.

Clin Immunol. 2008 Sep;128(3):400-8. doi: 10.1016/j.clim.2008.04.006. Epub 2008 Jun 20.


Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling.

Farhat K, Riekenberg S, Heine H, Debarry J, Lang R, Mages J, Buwitt-Beckmann U, Röschmann K, Jung G, Wiesmüller KH, Ulmer AJ.

J Leukoc Biol. 2008 Mar;83(3):692-701. Epub 2007 Dec 3.


Divergent roles of amino acid residues inside and outside the BB loop affect human Toll-like receptor (TLR)2/2, TLR2/1 and TLR2/6 responsiveness.

Qiu Y, Ding Y, Zou L, Tan Z, Liu T, Fu X, Xu W.

PLoS One. 2013 Apr 23;8(4):e61508. doi: 10.1371/journal.pone.0061508. Print 2013.


Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut.

Melmed G, Thomas LS, Lee N, Tesfay SY, Lukasek K, Michelsen KS, Zhou Y, Hu B, Arditi M, Abreu MT.

J Immunol. 2003 Feb 1;170(3):1406-15.


Therapeutic factor VIII does not trigger TLR1.2 and TLR2.6 signalling in vitro.

Teyssandier M, André S, Gupta N, Dasgupta S, Bayry J, Kaveri SV, Lacroix-Desmazes S; ABIRISK consortium.

Haemophilia. 2013 May;19(3):399-402. doi: 10.1111/hae.12081. Epub 2012 Dec 18.


IL-4 induces the intracellular expression of the alpha chain of the high-affinity receptor for IgE in in vitro-generated dendritic cells.

Geiger E, Magerstaedt R, Wessendorf JH, Kraft S, Hanau D, Bieber T.

J Allergy Clin Immunol. 2000 Jan;105(1 Pt 1):150-6.


TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes.

Oosting M, Ter Hofstede H, Sturm P, Adema GJ, Kullberg BJ, van der Meer JW, Netea MG, Joosten LA.

PLoS One. 2011;6(10):e25998. doi: 10.1371/journal.pone.0025998. Epub 2011 Oct 5.


Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.

Chang S, Dolganiuc A, Szabo G.

J Leukoc Biol. 2007 Sep;82(3):479-87. Epub 2007 Jun 26.


Engagement of the Fc epsilon RI stimulates the production of IL-16 in Langerhans cell-like dendritic cells.

Reich K, Heine A, Hugo S, Blaschke V, Middel P, Kaser A, Tilg H, Blaschke S, Gutgesell C, Neumann C.

J Immunol. 2001 Dec 1;167(11):6321-9.


Increased MAPK and NF-κB expression of Langerhans cells is dependent on TLR2 and TLR4, and increased IRF-3 expression is partially dependent on TLR4 following UV exposure.

Wang X, Bi Z, Wang Y, Wang Y.

Mol Med Rep. 2011 May-Jun;4(3):541-6. doi: 10.3892/mmr.2011.450. Epub 2011 Mar 8.


Induction of TLR2 expression by inflammatory stimuli is required for endothelial cell responses to lipopeptides.

Satta N, Kruithof EK, Reber G, de Moerloose P.

Mol Immunol. 2008 Nov;46(1):145-57. doi: 10.1016/j.molimm.2008.07.017. Epub 2008 Aug 23.


Lamina propria c-kit+ immune precursors reside in human adult intestine and differentiate into natural killer cells.

Chinen H, Matsuoka K, Sato T, Kamada N, Okamoto S, Hisamatsu T, Kobayashi T, Hasegawa H, Sugita A, Kinjo F, Fujita J, Hibi T.

Gastroenterology. 2007 Aug;133(2):559-73. Epub 2007 May 21.


Nod2 downregulates TLR2/1 mediated IL1β gene expression in mouse peritoneal macrophages.

Dahiya Y, Pandey RK, Sodhi A.

PLoS One. 2011;6(11):e27828. doi: 10.1371/journal.pone.0027828. Epub 2011 Nov 17.

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