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Items: 1 to 20 of 133

1.

Clonality, activated antigen-specific CD8(+) T cells, and development of autoimmune cholangitis in dnTGFβRII mice.

Kawata K, Yang GX, Ando Y, Tanaka H, Zhang W, Kobayashi Y, Tsuneyama K, Leung PS, Lian ZX, Ridgway WM, Ansari AA, He XS, Gershwin ME.

Hepatology. 2013 Sep;58(3):1094-104. doi: 10.1002/hep.26418. Epub 2013 Jul 24.

2.

Adoptive transfer of CD8(+) T cells from transforming growth factor beta receptor type II (dominant negative form) induces autoimmune cholangitis in mice.

Yang GX, Lian ZX, Chuang YH, Moritoki Y, Lan RY, Wakabayashi K, Ansari AA, Flavell RA, Ridgway WM, Coppel RL, Tsuneyama K, Mackay IR, Gershwin ME.

Hepatology. 2008 Jun;47(6):1974-82. doi: 10.1002/hep.22226.

3.

Murine autoimmune cholangitis requires two hits: cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells.

Huang W, Kachapati K, Adams D, Wu Y, Leung PS, Yang GX, Zhang W, Ansari AA, Flavell RA, Gershwin ME, Ridgway WM.

J Autoimmun. 2014 May;50:123-34. doi: 10.1016/j.jaut.2014.01.034. Epub 2014 Feb 18.

4.

Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor beta receptor type II mice.

Yoshida K, Yang GX, Zhang W, Tsuda M, Tsuneyama K, Moritoki Y, Ansari AA, Okazaki K, Lian ZX, Coppel RL, Mackay IR, Gershwin ME.

Hepatology. 2009 Nov;50(5):1494-500. doi: 10.1002/hep.23132.

5.

Differential priming of CD8 and CD4 T-cells in animal models of autoimmune hepatitis and cholangitis.

Derkow K, Loddenkemper C, Mintern J, Kruse N, Klugewitz K, Berg T, Wiedenmann B, Ploegh HL, Schott E.

Hepatology. 2007 Oct;46(4):1155-65.

PMID:
17657820
6.

Natural killer T cells exacerbate liver injury in a transforming growth factor beta receptor II dominant-negative mouse model of primary biliary cirrhosis.

Chuang YH, Lian ZX, Yang GX, Shu SA, Moritoki Y, Ridgway WM, Ansari AA, Kronenberg M, Flavell RA, Gao B, Gershwin ME.

Hepatology. 2008 Feb;47(2):571-80.

PMID:
18098320
7.

Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapy.

Yang JB, Wang YH, Yang W, Lu FT, Ma HD, Zhao ZB, Jia YJ, Tang W, Tsuneyama K, Ridgway WM, Gershwin ME, Lian ZX.

J Autoimmun. 2016 Jan;66:108-17. doi: 10.1016/j.jaut.2015.09.002. Epub 2015 Oct 1.

8.

Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse.

Ando Y, Yang GX, Kenny TP, Kawata K, Zhang W, Huang W, Leung PS, Lian ZX, Okazaki K, Ansari AA, He XS, Invernizzi P, Ridgway WM, Lu Q, Gershwin ME.

J Autoimmun. 2013 Mar;41:111-9. doi: 10.1016/j.jaut.2012.12.013. Epub 2013 Feb 8.

9.

Beta-glucosylceramide ameliorates liver inflammation in murine autoimmune cholangitis.

Zhang W, Moritoki Y, Tsuneyama K, Yang GX, Ilan Y, Lian ZX, Gershwin ME.

Clin Exp Immunol. 2009 Sep;157(3):359-64. doi: 10.1111/j.1365-2249.2009.03971.x.

10.

Disruption of TGF-β signaling improves ocular surface epithelial disease in experimental autoimmune keratoconjunctivitis sicca.

De Paiva CS, Volpe EA, Gandhi NB, Zhang X, Zheng X, Pitcher JD 3rd, Farley WJ, Stern ME, Niederkorn JY, Li DQ, Flavell RA, Pflugfelder SC.

PLoS One. 2011;6(12):e29017. doi: 10.1371/journal.pone.0029017. Epub 2011 Dec 14.

11.

CD8+ T cells undergo activation and programmed death-1 repression in the liver of aged Ae2a,b-/- mice favoring autoimmune cholangitis.

Concepcion AR, Salas JT, Sáez E, Sarvide S, Ferrer A, Portu A, Uriarte I, Hervás-Stubbs S, Oude Elferink RP, Prieto J, Medina JF.

Oncotarget. 2015 Oct 6;6(30):28588-606. doi: 10.18632/oncotarget.5665.

12.

Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice.

Oertelt S, Lian ZX, Cheng CM, Chuang YH, Padgett KA, He XS, Ridgway WM, Ansari AA, Coppel RL, Li MO, Flavell RA, Kronenberg M, Mackay IR, Gershwin ME.

J Immunol. 2006 Aug 1;177(3):1655-60.

13.

Truncated form of TGF-βRII, but not its absence, induces memory CD8+ T cell expansion and lymphoproliferative disorder in mice.

Ishigame H, Mosaheb MM, Sanjabi S, Flavell RA.

J Immunol. 2013 Jun 15;190(12):6340-50. doi: 10.4049/jimmunol.1300397. Epub 2013 May 17.

14.

Chemokine receptor CXCR3 deficiency exacerbates murine autoimmune cholangitis by promoting pathogenic CD8+ T cell activation.

Ma HD, Ma WT, Liu QZ, Zhao ZB, Liu MZ, Tsuneyama K, Gao JM, Ridgway WM, Ansari AA, Gershwin ME, Fei YY, Lian ZX.

J Autoimmun. 2017 Mar;78:19-28. doi: 10.1016/j.jaut.2016.12.012. Epub 2017 Jan 24.

PMID:
28129932
15.

Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells.

Tanaka H, Zhang W, Yang GX, Ando Y, Tomiyama T, Tsuneyama K, Leung P, Coppel RL, Ansari AA, Lian ZX, Ridgway WM, Joh T, Gershwin ME.

Clin Exp Immunol. 2014 Nov;178(2):253-61. doi: 10.1111/cei.12415.

16.

Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitis.

Zhang W, Tsuda M, Yang GX, Tsuneyama K, Rong G, Ridgway WM, Ansari AA, Flavell RA, Coppel RL, Lian ZX, Gershwin ME.

Hepatology. 2010 Jul;52(1):215-22. doi: 10.1002/hep.23664.

17.

Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice.

Tsuda M, Zhang W, Yang GX, Tsuneyama K, Ando Y, Kawata K, Park O, Leung PS, Coppel RL, Ansari AA, Ridgway WM, Gao B, Lian ZX, Flavell R, He XS, Gershwin ME.

Hepatology. 2013 Feb;57(2):806-16. doi: 10.1002/hep.25829.

18.

The immunobiology of colitis and cholangitis in interleukin-23p19 and interleukin-17A deleted dominant negative form of transforming growth factor beta receptor type II mice.

Ando Y, Yang GX, Tsuda M, Kawata K, Zhang W, Nakajima T, Tsuneyama K, Leung P, Lian ZX, Okazaki K, Ridgway WM, Norman GL, Ansari AA, He XS, Coppel RL, Gershwin ME.

Hepatology. 2012 Oct;56(4):1418-26. doi: 10.1002/hep.25803.

19.

Proteomic analysis reveals distinctive protein profiles involved in CD8+ T cell-mediated murine autoimmune cholangitis.

Zhang W, Zhang R, Zhang J, Sun Y, Leung PS, Yang GX, Shuai Z, Ridgway WM, Gershwin ME.

Cell Mol Immunol. 2018 Jan 29. doi: 10.1038/cmi.2017.149. [Epub ahead of print]

PMID:
29375127
20.

CD8 T cells primed in the gut-associated lymphoid tissue induce immune-mediated cholangitis in mice.

Seidel D, Eickmeier I, Kühl AA, Hamann A, Loddenkemper C, Schott E.

Hepatology. 2014 Feb;59(2):601-11. doi: 10.1002/hep.26702. Epub 2013 Dec 18.

PMID:
24038154

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