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Items: 1 to 20 of 113

1.
2.

Identification and functional characterization of nuclear mortalin in human carcinogenesis.

Ryu J, Kaul Z, Yoon AR, Liu Y, Yaguchi T, Na Y, Ahn HM, Gao R, Choi IK, Yun CO, Kaul SC, Wadhwa R.

J Biol Chem. 2014 Sep 5;289(36):24832-44. doi: 10.1074/jbc.M114.565929. Epub 2014 Jul 10.

3.

Mortalin (GRP75/HSPA9) upregulation promotes survival and proliferation of medullary thyroid carcinoma cells.

Starenki D, Hong SK, Lloyd RV, Park JI.

Oncogene. 2015 Aug 27;34(35):4624-34. doi: 10.1038/onc.2014.392. Epub 2014 Dec 1.

4.

From proliferative to neurological role of an hsp70 stress chaperone, mortalin.

Deocaris CC, Kaul SC, Wadhwa R.

Biogerontology. 2008 Dec;9(6):391-403. doi: 10.1007/s10522-008-9174-2. Epub 2008 Sep 4. Review.

PMID:
18770009
5.

An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: what, when, and where?

Wadhwa R, Taira K, Kaul SC.

Cell Stress Chaperones. 2002 Jul;7(3):309-16. Review.

6.

Druggability of mortalin for cancer and neuro-degenerative disorders.

Deocaris CC, Lu WJ, Kaul SC, Wadhwa R.

Curr Pharm Des. 2013;19(3):418-29. Review.

PMID:
22920904
7.

Secretion modification region-derived peptide disrupts HIV-1 Nef's interaction with mortalin and blocks virus and Nef exosome release.

Shelton MN, Huang MB, Ali SA, Powell MD, Bond VC.

J Virol. 2012 Jan;86(1):406-19. doi: 10.1128/JVI.05720-11. Epub 2011 Oct 19.

8.

Functional significance of point mutations in stress chaperone mortalin and their relevance to Parkinson disease.

Wadhwa R, Ryu J, Ahn HM, Saxena N, Chaudhary A, Yun CO, Kaul SC.

J Biol Chem. 2015 Mar 27;290(13):8447-56. doi: 10.1074/jbc.M114.627463. Epub 2015 Feb 2.

9.

TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas.

Klaus C, Kaemmerer E, Reinartz A, Schneider U, Plum P, Jeon MK, Hose J, Hartmann F, Schnölzer M, Wagner N, Kopitz J, Gassler N.

Cell Tissue Res. 2014 Jul;357(1):267-78. doi: 10.1007/s00441-014-1826-8. Epub 2014 Apr 29.

PMID:
24770931
10.
11.

Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis.

Wadhwa R, Takano S, Kaur K, Deocaris CC, Pereira-Smith OM, Reddel RR, Kaul SC.

Int J Cancer. 2006 Jun 15;118(12):2973-80.

12.

Tumor suppression by apoptotic and anti-angiogenic effects of mortalin-targeting adeno-oncolytic virus.

Yoo JY, Ryu J, Gao R, Yaguchi T, Kaul SC, Wadhwa R, Yun CO.

J Gene Med. 2010 Jul;12(7):586-95. doi: 10.1002/jgm.1471.

PMID:
20603860
13.

Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone.

Amick J, Schlanger SE, Wachnowsky C, Moseng MA, Emerson CC, Dare M, Luo WI, Ithychanda SS, Nix JC, Cowan JA, Page RC, Misra S.

Protein Sci. 2014 Jun;23(6):833-42. doi: 10.1002/pro.2466. Epub 2014 Apr 17.

14.

Down-regulation of mortalin exacerbates Aβ-mediated mitochondrial fragmentation and dysfunction.

Park SJ, Shin JH, Jeong JI, Song JH, Jo YK, Kim ES, Lee EH, Hwang JJ, Lee EK, Chung SJ, Koh JY, Jo DG, Cho DH.

J Biol Chem. 2014 Jan 24;289(4):2195-204. doi: 10.1074/jbc.M113.492587. Epub 2013 Dec 9.

15.

Mitochondrial Hspa9/Mortalin regulates erythroid differentiation via iron-sulfur cluster assembly.

Shan Y, Cortopassi G.

Mitochondrion. 2016 Jan;26:94-103. doi: 10.1016/j.mito.2015.12.005. Epub 2015 Dec 17.

PMID:
26702583
16.

Confinement exposure induces glucose regulated protein 75 (GRP75/mortalin/mtHsp70/PBP74/HSPA9B) in the hepatic tissue of gilthead sea bream (Sparus aurata L.).

Bermejo-Nogales A, Benedito-Palos L, Saera-Vila A, Calduch-Giner JA, Sitjà-Bobadilla A, Pérez-Sánchez J.

Comp Biochem Physiol B Biochem Mol Biol. 2008 Mar;149(3):428-38. doi: 10.1016/j.cbpb.2007.11.003. Epub 2007 Nov 24.

PMID:
18164226
17.

Reactivation of protein aggregates by mortalin and Tid1--the human mitochondrial Hsp70 chaperone system.

Iosefson O, Sharon S, Goloubinoff P, Azem A.

Cell Stress Chaperones. 2012 Jan;17(1):57-66. doi: 10.1007/s12192-011-0285-3. Epub 2011 Aug 3.

18.

Fibroblast growth factor-1 interacts with the glucose-regulated protein GRP75/mortalin.

Mizukoshi E, Suzuki M, Loupatov A, Uruno T, Hayashi H, Misono T, Kaul SC, Wadhwa R, Imamura T.

Biochem J. 1999 Oct 15;343 Pt 2:461-6.

19.

Cytoplasmic sequestration of the tumor suppressor p53 by a heat shock protein 70 family member, mortalin, in human colorectal adenocarcinoma cell lines.

Gestl EE, Anne Böttger S.

Biochem Biophys Res Commun. 2012 Jun 29;423(2):411-6. doi: 10.1016/j.bbrc.2012.05.139. Epub 2012 Jun 5.

PMID:
22683628

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