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1.

Phenothiazines inhibit hepatitis C virus entry, likely by increasing the fluidity of cholesterol-rich membranes.

Chamoun-Emanuelli AM, Pecheur EI, Simeon RL, Huang D, Cremer PS, Chen Z.

Antimicrob Agents Chemother. 2013 Jun;57(6):2571-81. doi: 10.1128/AAC.02593-12. Epub 2013 Mar 25.

2.

Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells.

Anggakusuma, Colpitts CC, Schang LM, Rachmawati H, Frentzen A, Pfaender S, Behrendt P, Brown RJ, Bankwitz D, Steinmann J, Ott M, Meuleman P, Rice CM, Ploss A, Pietschmann T, Steinmann E.

Gut. 2014 Jul;63(7):1137-49.

PMID:
23903236
3.

Human apolipoprotein E peptides inhibit hepatitis C virus entry by blocking virus binding.

Liu S, McCormick KD, Zhao W, Zhao T, Fan D, Wang T.

Hepatology. 2012 Aug;56(2):484-91. doi: 10.1002/hep.25665. Epub 2012 Jul 2.

4.

Up-regulation of the ATP-binding cassette transporter A1 inhibits hepatitis C virus infection.

Bocchetta S, Maillard P, Yamamoto M, Gondeau C, Douam F, Lebreton S, Lagaye S, Pol S, Helle F, Plengpanich W, Guérin M, Bourgine M, Michel ML, Lavillette D, Roingeard P, le Goff W, Budkowska A.

PLoS One. 2014 Mar 19;9(3):e92140. doi: 10.1371/journal.pone.0092140. eCollection 2014.

5.

Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action.

Calland N, Sahuc ME, Belouzard S, Pène V, Bonnafous P, Mesalam AA, Deloison G, Descamps V, Sahpaz S, Wychowski C, Lambert O, Brodin P, Duverlie G, Meuleman P, Rosenberg AR, Dubuisson J, Rouillé Y, Séron K.

J Virol. 2015 Oct;89(19):10053-63. doi: 10.1128/JVI.01473-15. Epub 2015 Jul 22.

6.

Specific inhibition of hepatitis C virus entry into host hepatocytes by fungi-derived sulochrin and its derivatives.

Nakajima S, Watashi K, Kamisuki S, Tsukuda S, Takemoto K, Matsuda M, Suzuki R, Aizaki H, Sugawara F, Wakita T.

Biochem Biophys Res Commun. 2013 Nov 1;440(4):515-20. doi: 10.1016/j.bbrc.2013.09.100. Epub 2013 Oct 5.

PMID:
24099774
7.

Benzhydrylpiperazine compounds inhibit cholesterol-dependent cellular entry of hepatitis C virus.

Chamoun-Emanuelli AM, Pécheur EI, Chen Z.

Antiviral Res. 2014 Sep;109:141-8. doi: 10.1016/j.antiviral.2014.06.014. Epub 2014 Jul 11.

PMID:
25019406
8.

Saikosaponin b2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry.

Lin LT, Chung CY, Hsu WC, Chang SP, Hung TC, Shields J, Russell RS, Lin CC, Li CF, Yen MH, Tyrrell DL, Lin CC, Richardson CD.

J Hepatol. 2015 Mar;62(3):541-8. doi: 10.1016/j.jhep.2014.10.040. Epub 2014 Nov 4. Erratum in: J Hepatol. 2015 Jul;63(1):292.

PMID:
25450204
9.

Antiviral activity of cuprous oxide nanoparticles against Hepatitis C Virus in vitro.

Hang X, Peng H, Song H, Qi Z, Miao X, Xu W.

J Virol Methods. 2015 Sep 15;222:150-7. doi: 10.1016/j.jviromet.2015.06.010. Epub 2015 Jun 25.

PMID:
26116793
10.

A Novel Class of Small Molecule Compounds that Inhibit Hepatitis C Virus Infection by Targeting the Prohibitin-CRaf Pathway.

Liu S, Wang W, Brown LE, Qiu C, Lajkiewicz N, Zhao T, Zhou J, Porco JA Jr, Wang TT.

EBioMedicine. 2015 Sep 14;2(11):1600-6. doi: 10.1016/j.ebiom.2015.09.018. eCollection 2015 Nov.

11.

Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies.

Zeisel MB, Fofana I, Fafi-Kremer S, Baumert TF.

J Hepatol. 2011 Mar;54(3):566-76. doi: 10.1016/j.jhep.2010.10.014. Epub 2010 Nov 11. Review.

12.

(-)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry.

Calland N, Albecka A, Belouzard S, Wychowski C, Duverlie G, Descamps V, Hober D, Dubuisson J, Rouillé Y, Séron K.

Hepatology. 2012 Mar;55(3):720-9. doi: 10.1002/hep.24803.

PMID:
22105803
13.

Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors.

Syder AJ, Lee H, Zeisel MB, Grove J, Soulier E, Macdonald J, Chow S, Chang J, Baumert TF, McKeating JA, McKelvy J, Wong-Staal F.

J Hepatol. 2011 Jan;54(1):48-55. doi: 10.1016/j.jhep.2010.06.024. Epub 2010 Aug 21.

PMID:
20932595
14.

Multiple effects of Honokiol on the life cycle of hepatitis C virus.

Lan KH, Wang YW, Lee WP, Lan KL, Tseng SH, Hung LR, Yen SH, Lin HC, Lee SD.

Liver Int. 2012 Jul;32(6):989-97. doi: 10.1111/j.1478-3231.2011.02621.x. Epub 2011 Aug 11.

PMID:
22098176
15.

A human claudin-1-derived peptide inhibits hepatitis C virus entry.

Si Y, Liu S, Liu X, Jacobs JL, Cheng M, Niu Y, Jin Q, Wang T, Yang W.

Hepatology. 2012 Aug;56(2):507-15. doi: 10.1002/hep.25685. Epub 2012 Jun 11.

16.

Tannic Acid Inhibits Hepatitis C Virus Entry into Huh7.5 Cells.

Liu S, Chen R, Hagedorn CH.

PLoS One. 2015 Jul 17;10(7):e0131358. doi: 10.1371/journal.pone.0131358. eCollection 2015.

17.

Hepatitis C viral entry inhibitors prolong viral suppression by replication inhibitors in persistently-infected Huh7 cultures.

Bush CO, Greenstein AE, Delaney WE 4th, Beran RK.

PLoS One. 2013 Jun 3;8(6):e65273. doi: 10.1371/journal.pone.0065273. Print 2013.

18.

Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor.

Sainz B Jr, Barretto N, Martin DN, Hiraga N, Imamura M, Hussain S, Marsh KA, Yu X, Chayama K, Alrefai WA, Uprichard SL.

Nat Med. 2012 Jan 8;18(2):281-5. doi: 10.1038/nm.2581.

19.

Limonium sinense and gallic acid suppress hepatitis C virus infection by blocking early viral entry.

Hsu WC, Chang SP, Lin LC, Li CL, Richardson CD, Lin CC, Lin LT.

Antiviral Res. 2015 Jun;118:139-47. doi: 10.1016/j.antiviral.2015.04.003. Epub 2015 Apr 9.

PMID:
25865056
20.

Monoclonal anti-claudin 1 antibodies prevent hepatitis C virus infection of primary human hepatocytes.

Fofana I, Krieger SE, Grunert F, Glauben S, Xiao F, Fafi-Kremer S, Soulier E, Royer C, Thumann C, Mee CJ, McKeating JA, Dragic T, Pessaux P, Stoll-Keller F, Schuster C, Thompson J, Baumert TF.

Gastroenterology. 2010 Sep;139(3):953-64, 964.e1-4. doi: 10.1053/j.gastro.2010.05.073. Epub 2010 Jun 2.

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