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Items: 1 to 20 of 102

1.
2.

Granulosa cell tumor mutant FOXL2C134W suppresses GDF-9 and activin A-induced follistatin transcription in primary granulosa cells.

McTavish KJ, Nonis D, Hoang YD, Shimasaki S.

Mol Cell Endocrinol. 2013 Jun 15;372(1-2):57-64. doi: 10.1016/j.mce.2013.03.021.

3.

FOXL2, GATA4, and SMAD3 co-operatively modulate gene expression, cell viability and apoptosis in ovarian granulosa cell tumor cells.

Anttonen M, Pihlajoki M, Andersson N, Georges A, L'hôte D, Vattulainen S, Färkkilä A, Unkila-Kallio L, Veitia RA, Heikinheimo M.

PLoS One. 2014 Jan 9;9(1):e85545. doi: 10.1371/journal.pone.0085545.

4.

Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter.

Fleming NI, Knower KC, Lazarus KA, Fuller PJ, Simpson ER, Clyne CD.

PLoS One. 2010 Dec 20;5(12):e14389. doi: 10.1371/journal.pone.0014389.

5.

FoxL2 and Smad3 coordinately regulate follistatin gene transcription.

Blount AL, Schmidt K, Justice NJ, Vale WW, Fischer WH, Bilezikjian LM.

J Biol Chem. 2009 Mar 20;284(12):7631-45. doi: 10.1074/jbc.M806676200.

6.

FOXL2-induced follistatin attenuates activin A-stimulated cell proliferation in human granulosa cell tumors.

Cheng JC, Chang HM, Qiu X, Fang L, Leung PC.

Biochem Biophys Res Commun. 2014 Jan 10;443(2):537-42. doi: 10.1016/j.bbrc.2013.12.010.

PMID:
24332943
7.

The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary.

Jamieson S, Butzow R, Andersson N, Alexiadis M, Unkila-Kallio L, Heikinheimo M, Fuller PJ, Anttonen M.

Mod Pathol. 2010 Nov;23(11):1477-85. doi: 10.1038/modpathol.2010.145.

8.
9.

Mutational analysis of FOXL2 p.C134W and expression of bone morphogenetic protein 2 in Japanese patients with granulosa cell tumor of ovary.

Oseto K, Suzumori N, Nishikawa R, Nishikawa H, Arakawa A, Ozaki Y, Asai H, Kawai M, Mizuno K, Takahashi S, Shirai T, Yamada-Namikawa C, Nakanishi M, Kajiyama H, Kikkawa F, Sugiura-Ogasawara M.

J Obstet Gynaecol Res. 2014 May;40(5):1197-204. doi: 10.1111/jog.12324.

PMID:
24689977
10.

Cooperative Effects of FOXL2 with the Members of TGF-β Superfamily on FSH Receptor mRNA Expression and Granulosa Cell Proliferation from Hen Prehierarchical Follicles.

Qin N, Fan XC, Xu XX, Tyasi TL, Li SJ, Zhang YY, Wei ML, Xu RF.

PLoS One. 2015 Oct 23;10(10):e0141062. doi: 10.1371/journal.pone.0141062.

11.

The transcriptional targets of mutant FOXL2 in granulosa cell tumours.

Rosario R, Araki H, Print CG, Shelling AN.

PLoS One. 2012;7(9):e46270. doi: 10.1371/journal.pone.0046270.

12.

Differential apoptotic activities of wild-type FOXL2 and the adult-type granulosa cell tumor-associated mutant FOXL2 (C134W).

Kim JH, Yoon S, Park M, Park HO, Ko JJ, Lee K, Bae J.

Oncogene. 2011 Apr 7;30(14):1653-63. doi: 10.1038/onc.2010.541.

PMID:
21119601
13.

Mutation of FOXL2 in granulosa-cell tumors of the ovary.

Shah SP, Köbel M, Senz J, Morin RD, Clarke BA, Wiegand KC, Leung G, Zayed A, Mehl E, Kalloger SE, Sun M, Giuliany R, Yorida E, Jones S, Varhol R, Swenerton KD, Miller D, Clement PB, Crane C, Madore J, Provencher D, Leung P, DeFazio A, Khattra J, Turashvili G, Zhao Y, Zeng T, Glover JN, Vanderhyden B, Zhao C, Parkinson CA, Jimenez-Linan M, Bowtell DD, Mes-Masson AM, Brenton JD, Aparicio SA, Boyd N, Hirst M, Gilks CB, Marra M, Huntsman DG.

N Engl J Med. 2009 Jun 25;360(26):2719-29. doi: 10.1056/NEJMoa0902542.

14.

SMADs and FOXL2 synergistically regulate murine FSHbeta transcription via a conserved proximal promoter element.

Tran S, Lamba P, Wang Y, Bernard DJ.

Mol Endocrinol. 2011 Jul;25(7):1170-83. doi: 10.1210/me.2010-0480.

PMID:
21622537
15.

Comparative study of microRNA regulation on FOXL2 between adult-type and juvenile-type granulosa cell tumours in vitro.

Rosario R, Blenkiron C, Shelling AN.

Gynecol Oncol. 2013 Apr;129(1):209-15. doi: 10.1016/j.ygyno.2012.12.034.

PMID:
23280087
16.

Identification and Validation of Differential Phosphorylation Sites of the Nuclear FOXL2 Protein as Potential Novel Biomarkers for Adult-Type Granulosa Cell Tumors.

Suh DS, Oh HK, Kim JH, Park S, Shin E, Lee K, Kim YH, Bae J.

J Proteome Res. 2015 Jun 5;14(6):2446-56. doi: 10.1021/pr501230b.

PMID:
25871347
17.

Discovery of novel protein partners of the transcription factor FOXL2 provides insights into its physiopathological roles.

L'Hôte D, Georges A, Todeschini AL, Kim JH, Benayoun BA, Bae J, Veitia RA.

Hum Mol Genet. 2012 Jul 15;21(14):3264-74. doi: 10.1093/hmg/dds170.

18.

Impact of FOXL2 mutations on signaling in ovarian granulosa cell tumors.

Leung DT, Fuller PJ, Chu S.

Int J Biochem Cell Biol. 2016 Mar;72:51-4. doi: 10.1016/j.biocel.2016.01.003. Review.

PMID:
26791928
19.

Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene.

Kuo FT, Bentsi-Barnes IK, Barlow GM, Bae J, Pisarska MD.

Cell Signal. 2009 Dec;21(12):1935-44. doi: 10.1016/j.cellsig.2009.09.001.

20.

FOXL2: a central transcription factor of the ovary.

Georges A, Auguste A, Bessière L, Vanet A, Todeschini AL, Veitia RA.

J Mol Endocrinol. 2013 Dec 19;52(1):R17-33. doi: 10.1530/JME-13-0159. Review.

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