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Items: 1 to 20 of 101

1.

Comparative proteomics identifies the cell-associated lethality of M. tuberculosis RelBE-like toxin-antitoxin complexes.

Miallau L, Jain P, Arbing MA, Cascio D, Phan T, Ahn CJ, Chan S, Chernishof I, Maxson M, Chiang J, Jacobs WR Jr, Eisenberg DS.

Structure. 2013 Apr 2;21(4):627-37. doi: 10.1016/j.str.2013.02.008. Epub 2013 Mar 21.

2.

Crystal structure of the antitoxin-toxin protein complex RelB-RelE from Methanococcus jannaschii.

Francuski D, Saenger W.

J Mol Biol. 2009 Nov 6;393(4):898-908. doi: 10.1016/j.jmb.2009.08.048. Epub 2009 Aug 25.

PMID:
19712680
3.

The Mycobacterium tuberculosis relBE toxin:antitoxin genes are stress-responsive modules that regulate growth through translation inhibition.

Korch SB, Malhotra V, Contreras H, Clark-Curtiss JE.

J Microbiol. 2015 Nov;53(11):783-95. doi: 10.1007/s12275-015-5333-8. Epub 2015 Oct 28. Erratum in: J Microbiol. 2015 Dec;53(12):875.

PMID:
26502963
4.

Crystal structure of Mycobacterium tuberculosis YefM antitoxin reveals that it is not an intrinsically unstructured protein.

Kumar P, Issac B, Dodson EJ, Turkenburg JP, Mande SC.

J Mol Biol. 2008 Nov 14;383(3):482-93. doi: 10.1016/j.jmb.2008.08.067. Epub 2008 Sep 4.

PMID:
18793646
5.

Amino acid residues crucial for specificity of toxin-antitoxin interactions in the homologous Axe-Txe and YefM-YoeB complexes.

Połom D, Boss L, Węgrzyn G, Hayes F, Kędzierska B.

FEBS J. 2013 Nov;280(22):5906-18. doi: 10.1111/febs.12517. Epub 2013 Sep 25.

6.

Structural and thermodynamic characterization of the Escherichia coli RelBE toxin-antitoxin system: indication for a functional role of differential stability.

Cherny I, Overgaard M, Borch J, Bram Y, Gerdes K, Gazit E.

Biochemistry. 2007 Oct 30;46(43):12152-63. Epub 2007 Oct 9.

PMID:
17924660
7.
8.

The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity.

Bøggild A, Sofos N, Andersen KR, Feddersen A, Easter AD, Passmore LA, Brodersen DE.

Structure. 2012 Oct 10;20(10):1641-8. doi: 10.1016/j.str.2012.08.017. Epub 2012 Sep 13.

9.

The Escherichia coli relBE genes belong to a new toxin-antitoxin gene family.

Gotfredsen M, Gerdes K.

Mol Microbiol. 1998 Aug;29(4):1065-76.

10.

Inhibitory mechanism of Escherichia coli RelE-RelB toxin-antitoxin module involves a helix displacement near an mRNA interferase active site.

Li GY, Zhang Y, Inouye M, Ikura M.

J Biol Chem. 2009 May 22;284(21):14628-36. doi: 10.1074/jbc.M809656200. Epub 2009 Mar 18.

11.

[Characterization of toxin-antitoxin systems in Mycobacterium tuberculosis].

Xian Y, Cui L, Zhang J.

Wei Sheng Wu Xue Bao. 2011 Feb;51(2):214-23. Chinese.

PMID:
21574383
12.

Interaction specificity, toxicity and regulation of a paralogous set of ParE/RelE-family toxin-antitoxin systems.

Fiebig A, Castro Rojas CM, Siegal-Gaskins D, Crosson S.

Mol Microbiol. 2010 Jul 1;77(1):236-51. doi: 10.1111/j.1365-2958.2010.07207.x. Epub 2010 May 12.

13.

Functional characterization of RelBE toxin-antitoxin system in probiotic Bifidobacterium longum JDM301.

Wei Y, Ye L, Li Y, Yang F, Liu D, Guo X, Tang R, Liu C.

Acta Biochim Biophys Sin (Shanghai). 2016 Aug;48(8):741-9. doi: 10.1093/abbs/gmw056. Epub 2016 Jul 22.

PMID:
27451444
14.

[RelE toxin protein of Mycobacterium tuberculosis induces growth inhibition of lung cancer A-549 cell].

Shi YL, Bao L, Shang ZL, Yao SX.

Sichuan Da Xue Xue Bao Yi Xue Ban. 2008 May;39(3):368-72. Chinese.

PMID:
18575317
15.

Structural mechanism of transcriptional autorepression of the Escherichia coli RelB/RelE antitoxin/toxin module.

Li GY, Zhang Y, Inouye M, Ikura M.

J Mol Biol. 2008 Jun 27;380(1):107-19. doi: 10.1016/j.jmb.2008.04.039. Epub 2008 Apr 22.

PMID:
18501926
16.

Structure of the Proteus vulgaris HigB-(HigA)2-HigB toxin-antitoxin complex.

Schureck MA, Maehigashi T, Miles SJ, Marquez J, Cho SE, Erdman R, Dunham CM.

J Biol Chem. 2014 Jan 10;289(2):1060-70. doi: 10.1074/jbc.M113.512095. Epub 2013 Nov 20.

17.

Prokaryotic toxin-antitoxin stress response loci.

Gerdes K, Christensen SK, Løbner-Olesen A.

Nat Rev Microbiol. 2005 May;3(5):371-82. Review.

PMID:
15864262
18.

Molecular structure and function of the novel BrnT/BrnA toxin-antitoxin system of Brucella abortus.

Heaton BE, Herrou J, Blackwell AE, Wysocki VH, Crosson S.

J Biol Chem. 2012 Apr 6;287(15):12098-110. doi: 10.1074/jbc.M111.332163. Epub 2012 Feb 14.

19.

The VapBC1 toxin-antitoxin complex from Mycobacterium tuberculosis: purification, crystallization and X-ray diffraction analysis.

Lu Z, Wang H, Zhang A, Tan Y.

Acta Crystallogr F Struct Biol Commun. 2016 Jun;72(Pt 6):485-9. doi: 10.1107/S2053230X16007603. Epub 2016 May 23.

PMID:
27303903
20.

Three Mycobacterium tuberculosis Rel toxin-antitoxin modules inhibit mycobacterial growth and are expressed in infected human macrophages.

Korch SB, Contreras H, Clark-Curtiss JE.

J Bacteriol. 2009 Mar;191(5):1618-30. doi: 10.1128/JB.01318-08. Epub 2008 Dec 29.

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