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Items: 1 to 20 of 203

1.
2.

Timp1 Promotes Cell Survival by Activating the PDK1 Signaling Pathway in Melanoma.

Toricelli M, Melo FHM, Hunger A, Zanatta D, Strauss BE, Jasiulionis MG.

Cancers (Basel). 2017 Apr 21;9(4). pii: E37. doi: 10.3390/cancers9040037.

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Erratum: Timp1 interacts with beta-1 integrin and CD63 along melanoma genesis and confers anoikis resistance by activating PI3-K signaling pathway independently of Akt phosphorylation.

Toricelli M, Melo FH, Peres GB, Silva DC, Jasiulionis MG.

Mol Cancer. 2015 Aug 22;14:161. doi: 10.1186/s12943-015-0405-2. No abstract available.

5.

Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes.

Beauséjour M, Noël D, Thibodeau S, Bouchard V, Harnois C, Beaulieu JF, Demers MJ, Vachon PH.

Apoptosis. 2012 Jun;17(6):566-78. doi: 10.1007/s10495-012-0713-6.

6.

Fak/Src signaling in human intestinal epithelial cell survival and anoikis: differentiation state-specific uncoupling with the PI3-K/Akt-1 and MEK/Erk pathways.

Bouchard V, Demers MJ, Thibodeau S, Laquerre V, Fujita N, Tsuruo T, Beaulieu JF, Gauthier R, Vézina A, Villeneuve L, Vachon PH.

J Cell Physiol. 2007 Sep;212(3):717-28.

PMID:
17443665
8.

Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver.

Grünwald B, Harant V, Schaten S, Frühschütz M, Spallek R, Höchst B, Stutzer K, Berchtold S, Erkan M, Prokopchuk O, Martignoni M, Esposito I, Heikenwalder M, Gupta A, Siveke J, Saftig P, Knolle P, Wohlleber D, Krüger A.

Gastroenterology. 2016 Nov;151(5):1011-1024.e7. doi: 10.1053/j.gastro.2016.07.043. Epub 2016 Aug 6.

PMID:
27506299
9.

The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion.

Fenouille N, Tichet M, Dufies M, Pottier A, Mogha A, Soo JK, Rocchi S, Mallavialle A, Galibert MD, Khammari A, Lacour JP, Ballotti R, Deckert M, Tartare-Deckert S.

PLoS One. 2012;7(7):e40378. doi: 10.1371/journal.pone.0040378. Epub 2012 Jul 20.

10.

Epigenetic reprogramming as a key contributor to melanocyte malignant transformation.

Molognoni F, Cruz AT, Meliso FM, Morais AS, Souza CF, Xander P, Bischof JM, Costa FF, Soares MB, Liang G, Jones PA, Jasiulionis MG.

Epigenetics. 2011 Apr;6(4):450-64. Epub 2011 Apr 1.

11.

Mining gene expression signature for the detection of pre-malignant melanocytes and early melanomas with risk for metastasis.

de Souza CF, Xander P, Monteiro AC, Silva AG, da Silva DC, Mai S, Bernardo V, Lopes JD, Jasiulionis MG.

PLoS One. 2012;7(9):e44800. doi: 10.1371/journal.pone.0044800. Epub 2012 Sep 11.

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Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells.

El Kharbili M, Robert C, Witkowski T, Danty-Berger E, Barbollat-Boutrand L, Masse I, Gadot N, de la Fouchardière A, McDonald PC, Dedhar S, Le Naour F, Degoul F, Berthier-Vergnes O.

Oncotarget. 2017 Mar 7;8(10):17140-17155. doi: 10.18632/oncotarget.15084.

14.

Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts.

Horowitz JC, Rogers DS, Sharma V, Vittal R, White ES, Cui Z, Thannickal VJ.

Cell Signal. 2007 Apr;19(4):761-71. Epub 2006 Nov 17.

15.

B1 integrin/Fak/Src signaling in intestinal epithelial crypt cell survival: integration of complex regulatory mechanisms.

Bouchard V, Harnois C, Demers MJ, Thibodeau S, Laquerre V, Gauthier R, Vézina A, Noël D, Fujita N, Tsuruo T, Arguin M, Vachon PH.

Apoptosis. 2008 Apr;13(4):531-42. doi: 10.1007/s10495-008-0192-y.

PMID:
18322799
16.

PI3-kinase p110α mediates β1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading.

Zeller KS, Idevall-Hagren O, Stefansson A, Velling T, Jackson SP, Downward J, Tengholm A, Johansson S.

Cell Signal. 2010 Dec;22(12):1838-48. doi: 10.1016/j.cellsig.2010.07.011. Epub 2010 Jul 25. Erratum in: Cell Signal. 2012 Apr;24(4):971-2.

PMID:
20667469
17.

Intestinal epithelial cancer cell anoikis resistance: EGFR-mediated sustained activation of Src overrides Fak-dependent signaling to MEK/Erk and/or PI3-K/Akt-1.

Demers MJ, Thibodeau S, Noël D, Fujita N, Tsuruo T, Gauthier R, Arguin M, Vachon PH.

J Cell Biochem. 2009 Jul 1;107(4):639-54. doi: 10.1002/jcb.22131.

PMID:
19479902
18.
19.

AEG-1 promotes anoikis resistance and orientation chemotaxis in hepatocellular carcinoma cells.

Zhou Z, Deng H, Yan W, Luo M, Tu W, Xia Y, He J, Han P, Fu Y, Tian D.

PLoS One. 2014 Jun 18;9(6):e100372. doi: 10.1371/journal.pone.0100372. eCollection 2014.

20.

Ras and Rac1, frequently mutated in melanomas, are activated by superoxide anion, modulate Dnmt1 level and are causally related to melanocyte malignant transformation.

Molognoni F, de Melo FH, da Silva CT, Jasiulionis MG.

PLoS One. 2013 Dec 16;8(12):e81937. doi: 10.1371/journal.pone.0081937. eCollection 2013. Erratum in: PLoS One. 2015;10(4):e0124983.

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