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Items: 1 to 20 of 113

1.

The metabolism of carbadox, olaquindox, mequindox, quinocetone and cyadox: an overview.

Liu ZY, Sun ZL.

Med Chem. 2013 Dec;9(8):1017-27. Review.

PMID:
23521002
2.

The critical role of oxidative stress in the toxicity and metabolism of quinoxaline 1,4-di-N-oxides in vitro and in vivo.

Wang X, Martínez MA, Cheng G, Liu Z, Huang L, Dai M, Chen D, Martínez-Larrañaga MR, Anadón A, Yuan Z.

Drug Metab Rev. 2016 May;48(2):159-82. doi: 10.1080/03602532.2016.1189560.

PMID:
27285897
3.

Hydroxylation of quinocetone and carbadox is mediated by CYP1As in the chicken (Gallus gallus).

Yang J, Liu Z, Li M, Qiu X.

Comp Biochem Physiol C Toxicol Pharmacol. 2013 Aug;158(2):84-90. doi: 10.1016/j.cbpc.2013.05.008.

PMID:
23726999
4.

N-oxide reduction of quinoxaline-1,4-dioxides catalyzed by porcine aldehyde oxidase SsAOX1.

Mu P, Zheng M, Xu M, Zheng Y, Tang X, Wang Y, Wu K, Chen Q, Wang L, Deng Y.

Drug Metab Dispos. 2014 Apr;42(4):511-9. doi: 10.1124/dmd.113.055418.

5.

Further investigations into the genotoxicity of quinoxaline-di-N-oxides and their primary metabolites.

Liu Q, Zhang J, Luo X, Ihsan A, Liu X, Dai M, Cheng G, Hao H, Wang X, Yuan Z.

Food Chem Toxicol. 2016 Jul;93:145-57. doi: 10.1016/j.fct.2016.04.029.

PMID:
27170491
6.

ROS mediated cytotoxicity of porcine adrenocortical cells induced by QdNOs derivatives in vitro.

Huang XJ, Zhang HH, Wang X, Huang LL, Zhang LY, Yan CX, Liu Y, Yuan ZH.

Chem Biol Interact. 2010 May 14;185(3):227-34. doi: 10.1016/j.cbi.2010.02.030.

PMID:
20188712
7.

High risk of adrenal toxicity of N1-desoxy quinoxaline 1,4-dioxide derivatives and the protection of oligomeric proanthocyanidins (OPC) in the inhibition of the expression of aldosterone synthetase in H295R cells.

Wang X, Yang C, Ihsan A, Luo X, Guo P, Cheng G, Dai M, Chen D, Liu Z, Yuan Z.

Toxicology. 2016 Feb 3;341-343:1-16. doi: 10.1016/j.tox.2016.01.005.

PMID:
26802905
8.

Deoxidation rates play a critical role in DNA damage mediated by important synthetic drugs, quinoxaline 1,4-dioxides.

Wang X, Zhang H, Huang L, Pan Y, Li J, Chen D, Cheng G, Hao H, Tao Y, Liu Z, Yuan Z.

Chem Res Toxicol. 2015 Mar 16;28(3):470-81. doi: 10.1021/tx5004326. Erratum in: Chem Res Toxicol. 2015 May 18;28(5):1070.

PMID:
25626015
9.

Photochemical reactions of quindoxin, olaquindox, carbadox and cyadox with protein, indicating photoallergic properties.

de Vries H, Bojarski J, Donker AA, Bakri A, Beyersbergen van Henegouwen GM.

Toxicology. 1990 Jul;63(1):85-95.

PMID:
2382272
10.

In vitro antimicrobial activities of animal-used quinoxaline 1,4-di-N-oxides against mycobacteria, mycoplasma and fungi.

Zhao Y, Cheng G, Hao H, Pan Y, Liu Z, Dai M, Yuan Z.

BMC Vet Res. 2016 Sep 6;12(1):186. doi: 10.1186/s12917-016-0812-7.

11.

The metabolism and N-oxide reduction of olaquindox in liver preparations of rats, pigs and chicken.

Liu ZY, Huang LL, Chen DM, Dai MH, Tao YF, Yuan ZH.

Toxicol Lett. 2010 May 19;195(1):51-9. doi: 10.1016/j.toxlet.2010.02.014.

PMID:
20219653
12.

The mechanism of enzymatic and non-enzymatic N-oxide reductive metabolism of cyadox in pig liver.

Zheng M, Jiang J, Wang J, Tang X, Ouyang M, Deng Y.

Xenobiotica. 2011 Nov;41(11):964-71. doi: 10.3109/00498254.2011.593207.

PMID:
21745143
13.

Genotoxicity of quinocetone, cyadox and olaquindox in vitro and in vivo.

Ihsan A, Wang X, Zhang W, Tu H, Wang Y, Huang L, Iqbal Z, Cheng G, Pan Y, Liu Z, Tan Z, Zhang Y, Yuan Z.

Food Chem Toxicol. 2013 Sep;59:207-14. doi: 10.1016/j.fct.2013.06.008.

PMID:
23774262
14.

Clinical signs and performance of pigs treated with different doses of carbadox, cyadox and olaquindox.

Nabuurs MJ, van der Molen EJ, de Graaf GJ, Jager LP.

Zentralbl Veterinarmed A. 1990 Feb;37(1):68-76.

PMID:
2110404
15.

In vivo studies to highlight possible illegal treatments of rabbits with carbadox and olaquindox.

Segato G, Biancotto G, Agnoletti F, Berto G, Montesissa C, Benetti C.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(12):1976-91. doi: 10.1080/19440049.2015.1086822.

PMID:
26400201
16.

A sensitive and specific ELISA for determining a residue marker of three quinoxaline antibiotics in swine liver.

Cheng L, Shen J, Wang Z, Jiang W, Zhang S.

Anal Bioanal Chem. 2013 Mar;405(8):2653-9. doi: 10.1007/s00216-012-6696-x.

PMID:
23354571
17.
18.

Investigation of the genotoxicity of quinocetone, carbadox and olaquindox in vitro using Vero cells.

Chen Q, Tang S, Jin X, Zou J, Chen K, Zhang T, Xiao X.

Food Chem Toxicol. 2009 Feb;47(2):328-34. doi: 10.1016/j.fct.2008.11.020.

PMID:
19061932
19.

Mechanism of porcine liver xanthine oxidoreductase mediated N-oxide reduction of cyadox as revealed by docking and mutagenesis studies.

Chen C, Cheng G, Hao H, Dai M, Wang X, Huang L, Liu Z, Yuan Z.

PLoS One. 2013 Sep 9;8(9):e73912. doi: 10.1371/journal.pone.0073912.

20.

Mechanisms of Antibacterial Action of Quinoxaline 1,4-di-N-oxides against Clostridium perfringens and Brachyspira hyodysenteriae.

Xu F, Cheng G, Hao H, Wang Y, Wang X, Chen D, Peng D, Liu Z, Yuan Z, Dai M.

Front Microbiol. 2016 Dec 5;7:1948. doi: 10.3389/fmicb.2016.01948.

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