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Items: 1 to 20 of 101

1.

Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands.

Tanji H, Ohto U, Shibata T, Miyake K, Shimizu T.

Science. 2013 Mar 22;339(6126):1426-9. doi: 10.1126/science.1229159.

2.

[Structural Analyses of Toll-like Receptor Sensing Single-stranded Nucleic Acids and Its Application].

Shimizu T.

Yakugaku Zasshi. 2016;136(2):173-8. doi: 10.1248/yakushi.15-00229-1. Review. Japanese.

3.

Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8.

Tanji H, Ohto U, Motoi Y, Shibata T, Miyake K, Shimizu T.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3012-7. doi: 10.1073/pnas.1516000113.

4.

Comparative analysis of species-specific ligand recognition in Toll-like receptor 8 signaling: a hypothesis.

Govindaraj RG, Manavalan B, Basith S, Choi S.

PLoS One. 2011;6(9):e25118. doi: 10.1371/journal.pone.0025118.

5.

Endosomal localization of TLR8 confers distinctive proteolytic processing on human myeloid cells.

Ishii N, Funami K, Tatematsu M, Seya T, Matsumoto M.

J Immunol. 2014 Nov 15;193(10):5118-28. doi: 10.4049/jimmunol.1401375.

6.

TLR7/8 agonists activate a mild immune response in rabbits through TLR8 but not TLR7.

Lai CY, Liu YL, Yu GY, Maa MC, Leu TH, Xu C, Luo Y, Xiang R, Chuang TH.

Vaccine. 2014 Sep 29;32(43):5593-9. doi: 10.1016/j.vaccine.2014.07.104.

PMID:
25131730
7.

The covalent modification and regulation of TLR8 in HEK-293 cells stimulated with imidazoquinoline agonists.

Rajagopal R, Waller AS, Mendoza JD, Wightman PD.

Biochem J. 2008 Jan 1;409(1):275-87.

PMID:
17868034
8.

Toll-like receptor 8 senses degradation products of single-stranded RNA.

Tanji H, Ohto U, Shibata T, Taoka M, Yamauchi Y, Isobe T, Miyake K, Shimizu T.

Nat Struct Mol Biol. 2015 Feb;22(2):109-15. doi: 10.1038/nsmb.2943.

PMID:
25599397
9.

Expression and function of Toll-like receptors in eosinophils: activation by Toll-like receptor 7 ligand.

Nagase H, Okugawa S, Ota Y, Yamaguchi M, Tomizawa H, Matsushima K, Ohta K, Yamamoto K, Hirai K.

J Immunol. 2003 Oct 15;171(8):3977-82.

10.

Characterization of bovine Toll-like receptor 8: ligand specificity, signaling essential sites and dimerization.

Zhu J, Brownlie R, Liu Q, Babiuk LA, Potter A, Mutwiri GK.

Mol Immunol. 2009 Feb;46(5):978-90. doi: 10.1016/j.molimm.2008.09.024.

PMID:
18995910
11.

Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains.

Wei T, Gong J, Jamitzky F, Heckl WM, Stark RW, Rössle SC.

Protein Sci. 2009 Aug;18(8):1684-91. doi: 10.1002/pro.186.

12.

Selective and direct activation of human neutrophils but not eosinophils by Toll-like receptor 8.

Janke M, Poth J, Wimmenauer V, Giese T, Coch C, Barchet W, Schlee M, Hartmann G.

J Allergy Clin Immunol. 2009 May;123(5):1026-33. doi: 10.1016/j.jaci.2009.02.015.

PMID:
19361845
13.

Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH.

de Bouteiller O, Merck E, Hasan UA, Hubac S, Benguigui B, Trinchieri G, Bates EE, Caux C.

J Biol Chem. 2005 Nov 18;280(46):38133-45.

14.

Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8.

Lan T, Kandimalla ER, Yu D, Bhagat L, Li Y, Wang D, Zhu F, Tang JX, Putta MR, Cong Y, Trombino AF, Sullivan T, Agrawal S.

Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13750-5.

15.
16.

Characterization of ovine TLR7 and TLR8 protein coding regions, detection of mutations and Maedi Visna virus infection.

Mikula I, Bhide M, Pastorekova S, Mikula I.

Vet Immunol Immunopathol. 2010 Nov 15;138(1-2):51-9. doi: 10.1016/j.vetimm.2010.06.015.

PMID:
20638136
17.

Modulating responsiveness of human TLR7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides.

Jurk M, Kritzler A, Schulte B, Tluk S, Schetter C, Krieg AM, Vollmer J.

Eur J Immunol. 2006 Jul;36(7):1815-26.

18.

TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation.

Larangé A, Antonios D, Pallardy M, Kerdine-Römer S.

J Leukoc Biol. 2009 Apr;85(4):673-83. doi: 10.1189/jlb.0808504.

PMID:
19164127
19.

Crystal structure of human toll-like receptor 3 (TLR3) ectodomain.

Choe J, Kelker MS, Wilson IA.

Science. 2005 Jul 22;309(5734):581-5.

20.
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