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Items: 1 to 20 of 104

1.

Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43.

Liu X, Biswas S, Berg MG, Antapli CM, Xie F, Wang Q, Tang MC, Tang GL, Zhang L, Dreyfuss G, Cheng YQ.

J Nat Prod. 2013 Apr 26;76(4):685-93. doi: 10.1021/np300913h.

2.

Cytotoxic Spliceostatins from Burkholderia sp. and Their Semisynthetic Analogues.

He H, Ratnayake AS, Janso JE, He M, Yang HY, Loganzo F, Shor B, O'Donnell CJ, Koehn FE.

J Nat Prod. 2014 Aug 22;77(8):1864-70. doi: 10.1021/np500342m.

PMID:
25098528
3.

Structural requirements for the antiproliferative activity of pre-mRNA splicing inhibitor FR901464.

Osman S, Albert BJ, Wang Y, Li M, Czaicki NL, Koide K.

Chemistry. 2011 Jan 17;17(3):895-904. doi: 10.1002/chem.201002402.

4.

New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.

Nakajima H, Sato B, Fujita T, Takase S, Terano H, Okuhara M.

J Antibiot (Tokyo). 1996 Dec;49(12):1196-203.

5.

Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities.

Wang C, Henkes LM, Doughty LB, He M, Wang D, Meyer-Almes FJ, Cheng YQ.

J Nat Prod. 2011 Oct 28;74(10):2031-8. doi: 10.1021/np200324x.

6.

Peniciketals A-C, new spiroketals from saline soil derived Penicillium raistrichii.

Liu WZ, Ma LY, Liu DS, Huang YL, Wang CH, Shi SS, Pan XH, Song XD, Zhu RX.

Org Lett. 2014 Jan 3;16(1):90-3. doi: 10.1021/ol403076s.

PMID:
24283621
7.

Antiproliferative bistramides from Trididemnum cyclops from Madagascar (1).

Murphy BT, Cao S, Brodie P, Maharavo J, Andriamanantoanina H, Ravelonandro P, Kingston DG.

J Nat Prod. 2009 Jul;72(7):1338-40. doi: 10.1021/np900072k.

8.

Histone deacetylase inhibitors from Burkholderia thailandensis.

Klausmeyer P, Shipley SM, Zuck KM, McCloud TG.

J Nat Prod. 2011 Oct 28;74(10):2039-44. doi: 10.1021/np200532d.

9.

Biosynthetic engineering and fermentation media development leads to gram-scale production of spliceostatin natural products in Burkholderia sp.

Eustáquio AS, Chang LP, Steele GL, O'Donnell CJ, Koehn FE.

Metab Eng. 2016 Jan;33:67-75. doi: 10.1016/j.ymben.2015.11.003.

PMID:
26620532
10.

Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells.

Albert BJ, McPherson PA, O'Brien K, Czaicki NL, Destefino V, Osman S, Li M, Day BW, Grabowski PJ, Moore MJ, Vogt A, Koide K.

Mol Cancer Ther. 2009 Aug;8(8):2308-18. doi: 10.1158/1535-7163.MCT-09-0051.

11.

A new cytotoxic 2H-pyran compound produced by acid treatment of the fermentation broth of Streptomyces sp.

Nosaka C, Kunimoto S, Masuda T, Ohsono M, Iinuma H, Tsuchida T, Hamada M, Takeuchi T.

Biol Pharm Bull. 1999 May;22(5):546-8.

PMID:
10375181
12.

New cytotoxic agents, BE-52440A and B, produced by a streptomycete.

Tsukamoto M, Nakajima S, Murooka K, Naito M, Suzuki H, Hirayama M, Hirano K, Kojiri K, Suda H.

J Antibiot (Tokyo). 2000 Jul;53(7):687-93.

13.

Cloning and elucidation of the FR901464 gene cluster revealing a complex acyltransferase-less polyketide synthase using glycerate as starter units.

Zhang F, He HY, Tang MC, Tang YM, Zhou Q, Tang GL.

J Am Chem Soc. 2011 Mar 2;133(8):2452-62. doi: 10.1021/ja105649g.

PMID:
21291275
14.

Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing.

Fan L, Lagisetti C, Edwards CC, Webb TR, Potter PM.

ACS Chem Biol. 2011 Jun 17;6(6):582-9. doi: 10.1021/cb100356k.

15.

Reveromycins, new inhibitors of eukaryotic cell growth. I. Producing organism, fermentation, isolation and physico-chemical properties.

Takahashi H, Osada H, Koshino H, Kudo T, Amano S, Shimizu S, Yoshihama M, Isono K.

J Antibiot (Tokyo). 1992 Sep;45(9):1409-13.

16.

Theopederins K and L. Highly potent cytotoxic metabolites from a marine sponge Discodermia species.

Paul GK, Gunasekera SP, Longley RE, Pomponi SA.

J Nat Prod. 2002 Jan;65(1):59-61.

PMID:
11809067
17.

Isolation and characterization of spliceostatin B, a new analogue of FR901464, from Pseudomonas sp. No. 2663.

Liu X, Biswas S, Tang GL, Cheng YQ.

J Antibiot (Tokyo). 2013 Sep;66(9):555-8. doi: 10.1038/ja.2013.38. No abstract available.

18.

Enantioselective synthesis of spliceostatin E and evaluation of biological activity.

Ghosh AK, Veitschegger AM, Sheri VR, Effenberger KA, Prichard BE, Jurica MS.

Org Lett. 2014 Dec 5;16(23):6200-3. doi: 10.1021/ol503127r.

19.

Isolation and identification of rhizoxin analogs from Pseudomonas fluorescens Pf-5 by using a genomic mining strategy.

Loper JE, Henkels MD, Shaffer BT, Valeriote FA, Gross H.

Appl Environ Microbiol. 2008 May;74(10):3085-93. doi: 10.1128/AEM.02848-07.

20.

Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates.

Sim BM, Chantratita N, Ooi WF, Nandi T, Tewhey R, Wuthiekanun V, Thaipadungpanit J, Tumapa S, Ariyaratne P, Sung WK, Sem XH, Chua HH, Ramnarayanan K, Lin CH, Liu Y, Feil EJ, Glass MB, Tan G, Peacock SJ, Tan P.

Genome Biol. 2010;11(8):R89. doi: 10.1186/gb-2010-11-8-r89.

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