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Items: 1 to 20 of 87


Antipurinergic therapy corrects the autism-like features in the poly(IC) mouse model.

Naviaux RK, Zolkipli Z, Wang L, Nakayama T, Naviaux JC, Le TP, Schuchbauer MA, Rogac M, Tang Q, Dugan LL, Powell SB.

PLoS One. 2013;8(3):e57380. doi: 10.1371/journal.pone.0057380. Epub 2013 Mar 13.


Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model.

Naviaux JC, Wang L, Li K, Bright AT, Alaynick WA, Williams KR, Powell SB, Naviaux RK.

Mol Autism. 2015 Jan 13;6:1. doi: 10.1186/2040-2392-6-1. eCollection 2015.


Reversal of autism-like behaviors and metabolism in adult mice with single-dose antipurinergic therapy.

Naviaux JC, Schuchbauer MA, Li K, Wang L, Risbrough VB, Powell SB, Naviaux RK.

Transl Psychiatry. 2014 Jun 17;4:e400. doi: 10.1038/tp.2014.33.


Gestational exposure to a viral mimetic poly(i:C) results in long-lasting changes in mitochondrial function by leucocytes in the adult offspring.

Giulivi C, Napoli E, Schwartzer J, Careaga M, Ashwood P.

Mediators Inflamm. 2013;2013:609602. doi: 10.1155/2013/609602. Epub 2013 Sep 19.


Involvement of CaM-CaMKII-ERK in bisphenol A-induced Sertoli cell apoptosis.

Qian W, Zhu J, Mao C, Liu J, Wang Y, Wang Q, Liu Y, Gao R, Xiao H, Wang J.

Toxicology. 2014 Oct 3;324:27-34. doi: 10.1016/j.tox.2014.06.001. Epub 2014 Jun 4.


P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase.

Panenka W, Jijon H, Herx LM, Armstrong JN, Feighan D, Wei T, Yong VW, Ransohoff RM, MacVicar BA.

J Neurosci. 2001 Sep 15;21(18):7135-42.


Association of upregulated Ras/Raf/ERK1/2 signaling with autism.

Zou H, Yu Y, Sheikh AM, Malik M, Yang K, Wen G, Chadman KK, Brown WT, Li X.

Genes Brain Behav. 2011 Jul;10(5):615-24. doi: 10.1111/j.1601-183X.2011.00702.x. Epub 2011 Jun 14. Retraction in: Genes Brain Behav. 2013 Jul;12(5):593.


Advances in behavioral genetics: mouse models of autism.

Moy SS, Nadler JJ.

Mol Psychiatry. 2008 Jan;13(1):4-26. Epub 2007 Sep 11. Review.


Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)- and ATP-dependent in MC3T3-E1 osteoblasts.

Liu D, Genetos DC, Shao Y, Geist DJ, Li J, Ke HZ, Turner CH, Duncan RL.

Bone. 2008 Apr;42(4):644-52. doi: 10.1016/j.bone.2007.09.058. Epub 2007 Oct 16.


Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.

Tsai PT, Hull C, Chu Y, Greene-Colozzi E, Sadowski AR, Leech JM, Steinberg J, Crawley JN, Regehr WG, Sahin M.

Nature. 2012 Aug 30;488(7413):647-51. doi: 10.1038/nature11310.


Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2.

Aguilar-Valles A, Matta-Camacho E, Khoutorsky A, Gkogkas C, Nader K, Lacaille JC, Sonenberg N.

J Neurosci. 2015 Aug 5;35(31):11125-32. doi: 10.1523/JNEUROSCI.4615-14.2015.


The α4β2 nicotinic acetylcholine receptor modulates autism-like behavioral and motor abnormalities in pentylenetetrazol-kindled mice.

Takechi K, Suemaru K, Kiyoi T, Tanaka A, Araki H.

Eur J Pharmacol. 2016 Mar 15;775:57-66. doi: 10.1016/j.ejphar.2016.02.021. Epub 2016 Feb 8.


Altered expression of Autism-associated genes in the brain of Fragile X mouse model.

Zhang A, Shen CH, Ma SY, Ke Y, El Idrissi A.

Biochem Biophys Res Commun. 2009 Feb 20;379(4):920-3. doi: 10.1016/j.bbrc.2008.12.172. Epub 2009 Jan 10.


Nicotinic receptor abnormalities in the cerebellar cortex in autism.

Lee M, Martin-Ruiz C, Graham A, Court J, Jaros E, Perry R, Iversen P, Bauman M, Perry E.

Brain. 2002 Jul;125(Pt 7):1483-95.


The genetics of autism.

Muhle R, Trentacoste SV, Rapin I.

Pediatrics. 2004 May;113(5):e472-86. Review.


Cerebellar Purkinje cell p75 neurotrophin receptor and autistic behavior.

Lotta LT, Conrad K, Cory-Slechta D, Schor NF.

Transl Psychiatry. 2014 Jul 29;4:e416. doi: 10.1038/tp.2014.55. Erratum in: Transl Psychiatry. 2014;4:e476.


Characterizing social behavior in genetically targeted mouse models of brain disorders.

Burrows EL, Hannan AJ.

Methods Mol Biol. 2013;1017:95-104. doi: 10.1007/978-1-62703-438-8_7.


P2X(7) receptor antagonists display agonist-like effects on cell signaling proteins.

Hedden L, Benes CH, Soltoff SP.

Biochim Biophys Acta. 2011 May;1810(5):532-42. doi: 10.1016/j.bbagen.2011.03.009. Epub 2011 Mar 21.


Loss of Tsc2 in Purkinje cells is associated with autistic-like behavior in a mouse model of tuberous sclerosis complex.

Reith RM, McKenna J, Wu H, Hashmi SS, Cho SH, Dash PK, Gambello MJ.

Neurobiol Dis. 2013 Mar;51:93-103. doi: 10.1016/j.nbd.2012.10.014. Epub 2012 Nov 1.


Purinergic receptor modulation of lipopolysaccharide signaling and inducible nitric-oxide synthase expression in RAW 264.7 macrophages.

Hu Y, Fisette PL, Denlinger LC, Guadarrama AG, Sommer JA, Proctor RA, Bertics PJ.

J Biol Chem. 1998 Oct 16;273(42):27170-5.

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