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Items: 1 to 20 of 126

1.

Kupffer cell-mediated hepatic injury induced by silica nanoparticles in vitro and in vivo.

Chen Q, Xue Y, Sun J.

Int J Nanomedicine. 2013;8:1129-40. doi: 10.2147/IJN.S42242. Epub 2013 Mar 15.

2.

SiO₂ nanoparticle-induced impairment of mitochondrial energy metabolism in hepatocytes directly and through a Kupffer cell-mediated pathway in vitro.

Xue Y, Chen Q, Ding T, Sun J.

Int J Nanomedicine. 2014 Jun 12;9:2891-903. doi: 10.2147/IJN.S60661. eCollection 2014.

3.

Hepatotoxicity and liver injury induced by hydroxyapatite nanoparticles.

Chen Q, Xue Y, Sun J.

J Appl Toxicol. 2014 Nov;34(11):1256-64. doi: 10.1002/jat.3073. Epub 2014 Sep 16.

PMID:
25225040
4.

Amphipathic silica nanoparticles induce cytotoxicity through oxidative stress mediated and p53 dependent apoptosis pathway in human liver cell line HL-7702 and rat liver cell line BRL-3A.

Zuo D, Duan Z, Jia Y, Chu T, He Q, Yuan J, Dai W, Li Z, Xing L, Wu Y.

Colloids Surf B Biointerfaces. 2016 Sep 1;145:232-40. doi: 10.1016/j.colsurfb.2016.05.006. Epub 2016 May 5.

PMID:
27187187
5.

Carbon monoxide induces hypothermia tolerance in Kupffer cells and attenuates liver ischemia/reperfusion injury in rats.

Lee LY, Kaizu T, Toyokawa H, Zhang M, Ross M, Stolz DB, Huang C, Gandhi C, Geller DA, Murase N.

Liver Transpl. 2011 Dec;17(12):1457-66. doi: 10.1002/lt.22415.

6.

Depletion of Kupffer cells modulates ethanol-induced hepatocyte DNA synthesis in C57Bl/6 mice.

Owumi SE, Corthals SM, Uwaifo AO, Kamendulis LM, Klaunig JE.

Environ Toxicol. 2014 Aug;29(8):867-75. doi: 10.1002/tox.21814. Epub 2012 Sep 20.

PMID:
22996800
7.

Suppression of Kupffer cell function prevents cadmium induced hepatocellular necrosis in the male Sprague-Dawley rat.

Sauer JM, Waalkes MP, Hooser SB, Kuester RK, McQueen CA, Sipes IG.

Toxicology. 1997 Aug 15;121(2):155-64.

PMID:
9230447
8.
9.

Direct cell-to-cell contact between Kupffer cells and hepatocytes augments endotoxin-induced hepatic injury.

Hoebe KH, Witkamp RF, Fink-Gremmels J, Van Miert AS, Monshouwer M.

Am J Physiol Gastrointest Liver Physiol. 2001 Apr;280(4):G720-8.

10.

Influence of hyperthyroidism on lindane-induced hepatotoxicity in the rat.

Videla LA, Smok G, Troncoso P, Simon KA, Junqueira VB, Fernández V.

Biochem Pharmacol. 1995 Nov 9;50(10):1557-65.

PMID:
7503757
11.

Upregulation of Kupffer cell α2A-Adrenoceptors and downregulation of MKP-1 mediate hepatic injury in chronic alcohol exposure.

Ajakaiye MA, Jacob A, Wu R, Zhou M, Ji Y, Dong W, Wang Z, Qiang X, Chaung WW, Nicastro J, Coppa GF, Wang P.

Biochem Biophys Res Commun. 2011 Jun 10;409(3):406-11. doi: 10.1016/j.bbrc.2011.05.007. Epub 2011 May 7.

12.

Silica nanoparticles-induced cytotoxicity, oxidative stress and apoptosis in cultured A431 and A549 cells.

Ahamed M.

Hum Exp Toxicol. 2013 Feb;32(2):186-95. doi: 10.1177/0960327112459206.

PMID:
23315277
13.

Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance.

Huang W, Metlakunta A, Dedousis N, Zhang P, Sipula I, Dube JJ, Scott DK, O'Doherty RM.

Diabetes. 2010 Feb;59(2):347-57. doi: 10.2337/db09-0016. Epub 2009 Nov 23.

14.

Oxidative stress increased hepatotoxicity induced by nano-titanium dioxide in BRL-3A cells and Sprague-Dawley rats.

Sha B, Gao W, Wang S, Gou X, Li W, Liang X, Qu Z, Xu F, Lu TJ.

J Appl Toxicol. 2014 Apr;34(4):345-56. doi: 10.1002/jat.2900. Epub 2013 Jul 22.

PMID:
23873220
16.

Kupffer cells are associated with apoptosis, inflammation and fibrotic effects in hepatic fibrosis in rats.

Liu C, Tao Q, Sun M, Wu JZ, Yang W, Jian P, Peng J, Hu Y, Liu C, Liu P.

Lab Invest. 2010 Dec;90(12):1805-16. doi: 10.1038/labinvest.2010.123. Epub 2010 Oct 4.

17.

Silica nanoparticles and silver-doped silica nanoparticles induce endoplasmatic reticulum stress response and alter cytochrome P4501A activity.

Christen V, Fent K.

Chemosphere. 2012 Apr;87(4):423-34. doi: 10.1016/j.chemosphere.2011.12.046. Epub 2012 Jan 13.

PMID:
22245057
18.

NMR-based metabonomics study of sub-acute hepatotoxicity induced by silica nanoparticles in rats after intranasal exposure.

Parveen A, Rizvi SH, Gupta A, Singh R, Ahmad I, Mahdi F, Mahdi AA.

Cell Mol Biol (Noisy-le-grand). 2012 Dec 22;58(1):196-203.

PMID:
23273212
19.

Exacerbation of acetaminophen-induced disturbances of liver sinusoidal endothelial cells in the absence of Kupffer cells in mice.

Holt MP, Yin H, Ju C.

Toxicol Lett. 2010 Apr 15;194(1-2):34-41. doi: 10.1016/j.toxlet.2010.01.020. Epub 2010 Feb 1.

PMID:
20123118
20.

Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis.

Roberts RA, Ganey PE, Ju C, Kamendulis LM, Rusyn I, Klaunig JE.

Toxicol Sci. 2007 Mar;96(1):2-15. Epub 2006 Nov 22. Review.

PMID:
17122412

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