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Items: 1 to 20 of 138


An allelic series at the paired box gene 6 (Pax6) locus reveals the functional specificity of Pax genes.

Carbe C, Garg A, Cai Z, Li H, Powers A, Zhang X.

J Biol Chem. 2013 Apr 26;288(17):12130-41. doi: 10.1074/jbc.M112.436865. Epub 2013 Mar 20.


Eye-specific expression of an ancestral jellyfish PaxB gene interferes with Pax6 function despite its conserved Pax6/Pax2 characteristics.

Ruzickova J, Piatigorsky J, Kozmik Z.

Int J Dev Biol. 2009;53(4):469-82. doi: 10.1387/ijdb.082793jr.


Dmrta1 regulates proneural gene expression downstream of Pax6 in the mammalian telencephalon.

Kikkawa T, Obayashi T, Takahashi M, Fukuzaki-Dohi U, Numayama-Tsuruta K, Osumi N.

Genes Cells. 2013 Aug;18(8):636-49. doi: 10.1111/gtc.12061. Epub 2013 May 16.


Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice.

Simpson TI, Pratt T, Mason JO, Price DJ.

Neural Dev. 2009 Jun 5;4:19. doi: 10.1186/1749-8104-4-19.


Pax6-dependence of Six3, Eya1 and Dach1 expression during lens and nasal placode induction.

Purcell P, Oliver G, Mardon G, Donner AL, Maas RL.

Gene Expr Patterns. 2005 Dec;6(1):110-8. Epub 2005 Jul 18.


Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development.

Huettl RE, Eckstein S, Stahl T, Petricca S, Ninkovic J, Götz M, Huber AB.

Dev Biol. 2016 May 1;413(1):86-103. doi: 10.1016/j.ydbio.2015.07.009. Epub 2015 Jul 15.


Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1.

Pratt T, Quinn JC, Simpson TI, West JD, Mason JO, Price DJ.

J Neurosci. 2002 Oct 1;22(19):8523-31.


Cdc42-mTOR signaling pathway controls Hes5 and Pax6 expression in retinoic acid-dependent neural differentiation.

Endo M, Antonyak MA, Cerione RA.

J Biol Chem. 2009 Feb 20;284(8):5107-18. doi: 10.1074/jbc.M807745200. Epub 2008 Dec 19.


Identification of pax6-dependent gene regulatory networks in the mouse lens.

Wolf LV, Yang Y, Wang J, Xie Q, Braunger B, Tamm ER, Zavadil J, Cvekl A.

PLoS One. 2009;4(1):e4159. doi: 10.1371/journal.pone.0004159. Epub 2009 Jan 9. Erratum in: PLoS ONE. 2009;4(3). doi: 10.1371/annotation/71d78295-dc0f-4e78-9c99-45b730952d9b.


Pax6- and Six3-mediated induction of lens cell fate in mouse and human ES cells.

Anchan RM, Lachke SA, Gerami-Naini B, Lindsey J, Ng N, Naber C, Nickerson M, Cavallesco R, Rowan S, Eaton JL, Xi Q, Maas RL.

PLoS One. 2014 Dec 17;9(12):e115106. doi: 10.1371/journal.pone.0115106. eCollection 2014.


Neurotrophin receptor-mediated death of misspecified neurons generated from embryonic stem cells lacking Pax6.

Nikoletopoulou V, Plachta N, Allen ND, Pinto L, Götz M, Barde YA.

Cell Stem Cell. 2007 Nov;1(5):529-40. doi: 10.1016/j.stem.2007.08.011.


Removal of Pax6 partially rescues the loss of ventral structures in Shh null mice.

Fuccillo M, Rutlin M, Fishell G.

Cereb Cortex. 2006 Jul;16 Suppl 1:i96-102.


Overexpression of PAX6(5a) in lens fiber cells results in cataract and upregulation of (alpha)5(beta)1 integrin expression.

Duncan MK, Kozmik Z, Cveklova K, Piatigorsky J, Cvekl A.

J Cell Sci. 2000 Sep;113 ( Pt 18):3173-85.


The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.

Xie Q, Cvekl A.

J Biol Chem. 2011 Dec 16;286(50):43259-71. doi: 10.1074/jbc.M111.264580. Epub 2011 Oct 13.


Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development.

Sun J, Rockowitz S, Xie Q, Ashery-Padan R, Zheng D, Cvekl A.

Nucleic Acids Res. 2015 Aug 18;43(14):6827-46. doi: 10.1093/nar/gkv589. Epub 2015 Jul 2.


Stage-dependent requirement of neuroretinal Pax6 for lens and retina development.

Klimova L, Kozmik Z.

Development. 2014 Mar;141(6):1292-302. doi: 10.1242/dev.098822. Epub 2014 Feb 12.


Isoform- and dose-sensitive feedback interactions between paired box 6 gene and delta-catenin in cell differentiation and death.

Zhang J, Lu JP, Suter DM, Krause KH, Fini ME, Chen B, Lu Q.

Exp Cell Res. 2010 Apr 1;316(6):1070-81. doi: 10.1016/j.yexcr.2010.01.006. Epub 2010 Jan 11.


Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain.

Xie Q, Yang Y, Huang J, Ninkovic J, Walcher T, Wolf L, Vitenzon A, Zheng D, Götz M, Beebe DC, Zavadil J, Cvekl A.

PLoS One. 2013;8(1):e54507. doi: 10.1371/journal.pone.0054507. Epub 2013 Jan 14.


The functional role of the Meis/Prep-binding elements in Pax6 locus during pancreas and eye development.

Carbe C, Hertzler-Schaefer K, Zhang X.

Dev Biol. 2012 Mar 1;363(1):320-9. doi: 10.1016/j.ydbio.2011.12.038. Epub 2012 Jan 3.

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