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Items: 1 to 20 of 92

1.

AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?

Dandapani M, Hardie DG.

Biochem Soc Trans. 2013 Apr;41(2):687-93. doi: 10.1042/BST20120351. Review.

2.

AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease.

Grahame Hardie D.

J Intern Med. 2014 Dec;276(6):543-59. doi: 10.1111/joim.12268. Review.

3.

Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?

Hardie DG.

Clin Cancer Res. 2015 Sep 1;21(17):3836-40. doi: 10.1158/1078-0432.CCR-14-3300. Review.

4.

Metabolism of inflammation limited by AMPK and pseudo-starvation.

O'Neill LA, Hardie DG.

Nature. 2013 Jan 17;493(7432):346-55. doi: 10.1038/nature11862. Review.

PMID:
23325217
5.

Effects of sorafenib on energy metabolism in breast cancer cells: role of AMPK-mTORC1 signaling.

Fumarola C, Caffarra C, La Monica S, Galetti M, Alfieri RR, Cavazzoni A, Galvani E, Generali D, Petronini PG, Bonelli MA.

Breast Cancer Res Treat. 2013 Aug;141(1):67-78. doi: 10.1007/s10549-013-2668-x.

PMID:
23963659
6.
7.

AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo.

Faubert B, Boily G, Izreig S, Griss T, Samborska B, Dong Z, Dupuy F, Chambers C, Fuerth BJ, Viollet B, Mamer OA, Avizonis D, DeBerardinis RJ, Siegel PM, Jones RG.

Cell Metab. 2013 Jan 8;17(1):113-24. doi: 10.1016/j.cmet.2012.12.001.

8.

AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer.

Hardie DG.

Biochem Soc Trans. 2011 Jan;39(1):1-13. doi: 10.1042/BST0390001.

PMID:
21265739
9.

AMP-activated protein kinase influences metabolic remodeling in H9c2 cells hypertrophied by arginine vasopressin.

Saeedi R, Saran VV, Wu SS, Kume ES, Paulson K, Chan AP, Parsons HL, Wambolt RB, Dyck JR, Brownsey RW, Allard MF.

Am J Physiol Heart Circ Physiol. 2009 Jun;296(6):H1822-32. doi: 10.1152/ajpheart.00396.2008.

10.

Oligomycin-induced bioenergetic adaptation in cancer cells with heterogeneous bioenergetic organization.

Hao W, Chang CP, Tsao CC, Xu J.

J Biol Chem. 2010 Apr 23;285(17):12647-54. doi: 10.1074/jbc.M109.084194.

11.

AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress.

Jeon SM, Chandel NS, Hay N.

Nature. 2012 May 9;485(7400):661-5. doi: 10.1038/nature11066.

12.

Role of AMP-activated protein kinase in cancer therapy.

Rehman G, Shehzad A, Khan AL, Hamayun M.

Arch Pharm (Weinheim). 2014 Jul;347(7):457-68. doi: 10.1002/ardp.201300402. Review.

PMID:
24677093
13.

Sensing of energy and nutrients by AMP-activated protein kinase.

Hardie DG.

Am J Clin Nutr. 2011 Apr;93(4):891S-6. doi: 10.3945/ajcn.110.001925. Review.

14.

2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways.

Li CM, Narayanan R, Lu Y, Hurh E, Coss CC, Barrett CM, Miller DD, Dalton JT.

Int J Oncol. 2010 Oct;37(4):1023-30.

PMID:
20811725
15.

The AMP-activated protein kinase (AMPK) and cancer: many faces of a metabolic regulator.

Faubert B, Vincent EE, Poffenberger MC, Jones RG.

Cancer Lett. 2015 Jan 28;356(2 Pt A):165-70. doi: 10.1016/j.canlet.2014.01.018. Review.

PMID:
24486219
16.

5'-AMP-activated protein kinase (AMPK) supports the growth of aggressive experimental human breast cancer tumors.

Laderoute KR, Calaoagan JM, Chao WR, Dinh D, Denko N, Duellman S, Kalra J, Liu X, Papandreou I, Sambucetti L, Boros LG.

J Biol Chem. 2014 Aug 15;289(33):22850-64. doi: 10.1074/jbc.M114.576371.

17.

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.

Shaw RJ.

Acta Physiol (Oxf). 2009 May;196(1):65-80. doi: 10.1111/j.1748-1716.2009.01972.x. Review.

18.

Dissecting the Dual Role of AMPK in Cancer: From Experimental to Human Studies.

Zadra G, Batista JL, Loda M.

Mol Cancer Res. 2015 Jul;13(7):1059-72. doi: 10.1158/1541-7786.MCR-15-0068. Review.

19.

Energy sensing by the AMP-activated protein kinase and its effects on muscle metabolism.

Hardie DG.

Proc Nutr Soc. 2011 Feb;70(1):92-9. doi: 10.1017/S0029665110003915. Review.

PMID:
21067629
20.

The Warburg effect then and now: from cancer to inflammatory diseases.

Palsson-McDermott EM, O'Neill LA.

Bioessays. 2013 Nov;35(11):965-73. doi: 10.1002/bies.201300084. Review.

PMID:
24115022

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