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Effects of prolonged fasting on AMPK signaling, gene expression, and mitochondrial respiratory chain content in skeletal muscle from lean and obese individuals.

Wijngaarden MA, van der Zon GC, van Dijk KW, Pijl H, Guigas B.

Am J Physiol Endocrinol Metab. 2013 May 1;304(9):E1012-21. doi: 10.1152/ajpendo.00008.2013. Epub 2013 Mar 19.


Interactions between the consumption of a high-fat diet and fasting in the regulation of fatty acid oxidation enzyme gene expression: an evaluation of potential mechanisms.

Frier BC, Jacobs RL, Wright DC.

Am J Physiol Regul Integr Comp Physiol. 2011 Feb;300(2):R212-21. doi: 10.1152/ajpregu.00367.2010. Epub 2010 Nov 17.


Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1 alpha and PPAR beta/delta gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus.

Mensink M, Hesselink MK, Russell AP, Schaart G, Sels JP, Schrauwen P.

Int J Obes (Lond). 2007 Aug;31(8):1302-10. Epub 2007 Feb 20.


Skeletal muscle mitochondria in insulin resistance: differences in intermyofibrillar versus subsarcolemmal subpopulations and relationship to metabolic flexibility.

Chomentowski P, Coen PM, Radiková Z, Goodpaster BH, Toledo FG.

J Clin Endocrinol Metab. 2011 Feb;96(2):494-503. doi: 10.1210/jc.2010-0822. Epub 2010 Nov 24.


Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1alpha) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats.

Benton CR, Holloway GP, Han XX, Yoshida Y, Snook LA, Lally J, Glatz JF, Luiken JJ, Chabowski A, Bonen A.

Diabetologia. 2010 Sep;53(9):2008-19. doi: 10.1007/s00125-010-1773-1. Epub 2010 May 20.


Regulation of skeletal muscle energy/nutrient-sensing pathways during metabolic adaptation to fasting in healthy humans.

Wijngaarden MA, Bakker LE, van der Zon GC, 't Hoen PA, van Dijk KW, Jazet IM, Pijl H, Guigas B.

Am J Physiol Endocrinol Metab. 2014 Nov 15;307(10):E885-95. doi: 10.1152/ajpendo.00215.2014. Epub 2014 Sep 23.


The effects of altitude training on the AMPK-related glucose transport pathway in the red skeletal muscle of both lean and obese Zucker rats.

Chen YC, Lee SD, Kuo CH, Ho LT.

High Alt Med Biol. 2011 Winter;12(4):371-8. doi: 10.1089/ham.2010.1088.


LKB1-AMPK signaling in muscle from obese insulin-resistant Zucker rats and effects of training.

Sriwijitkamol A, Ivy JL, Christ-Roberts C, DeFronzo RA, Mandarino LJ, Musi N.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E925-32. Epub 2005 Dec 13.


PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein.

Holloway GP, Perry CG, Thrush AB, Heigenhauser GJ, Dyck DJ, Bonen A, Spriet LL.

Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E1060-9. doi: 10.1152/ajpendo.00726.2007. Epub 2008 Mar 18.


Skeletal muscle respiratory capacity is enhanced in rats consuming an obesogenic Western diet.

Stephenson EJ, Camera DM, Jenkins TA, Kosari S, Lee JS, Hawley JA, Stepto NK.

Am J Physiol Endocrinol Metab. 2012 Jun 15;302(12):E1541-9. doi: 10.1152/ajpendo.00590.2011. Epub 2012 Apr 10.


Parenteral 17beta-estradiol decreases fasting blood glucose levels in non-obese mice with short-term ovariectomy.

Kim JY, Jo KJ, Kim OS, Kim BJ, Kang DW, Lee KH, Baik HW, Han MS, Lee SK.

Life Sci. 2010 Sep 11;87(11-12):358-66. doi: 10.1016/j.lfs.2010.07.009. Epub 2010 Jul 23.


AICAR treatment for 14 days normalizes obesity-induced dysregulation of TORC1 signaling and translational capacity in fasted skeletal muscle.

Drake JC, Alway SE, Hollander JM, Williamson DL.

Am J Physiol Regul Integr Comp Physiol. 2010 Dec;299(6):R1546-54. doi: 10.1152/ajpregu.00337.2010. Epub 2010 Sep 15.


Relationship between plasma free fatty acids and uncoupling protein-3 gene expression in skeletal muscle of obese subjects: in vitro evidence of a causal link.

Sbraccia P, D'Adamo M, Leonetti F, Buongiorno A, Silecchia G, Basso MS, Tamburrano G, Lauro D, Federici M, Di Daniele N, Lauro R.

Clin Endocrinol (Oxf). 2002 Aug;57(2):199-207.


Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individuals.

Holloway GP, Bonen A, Spriet LL.

Am J Clin Nutr. 2009 Jan;89(1):455S-62S. doi: 10.3945/ajcn.2008.26717B. Epub 2008 Dec 3. Review.


Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study.

Sriwijitkamol A, Coletta DK, Wajcberg E, Balbontin GB, Reyna SM, Barrientes J, Eagan PA, Jenkinson CP, Cersosimo E, DeFronzo RA, Sakamoto K, Musi N.

Diabetes. 2007 Mar;56(3):836-48.


AMP-activated protein kinase is required for exercise-induced peroxisome proliferator-activated receptor co-activator 1 translocation to subsarcolemmal mitochondria in skeletal muscle.

Smith BK, Mukai K, Lally JS, Maher AC, Gurd BJ, Heigenhauser GJ, Spriet LL, Holloway GP.

J Physiol. 2013 Mar 15;591(6):1551-61. doi: 10.1113/jphysiol.2012.245944. Epub 2013 Jan 7.


The role of leptin in human lipid and glucose metabolism: the effects of acute recombinant human leptin infusion in young healthy males.

Wolsk E, Mygind H, Grøndahl TS, Pedersen BK, van Hall G.

Am J Clin Nutr. 2011 Dec;94(6):1533-44. doi: 10.3945/ajcn.111.012260. Epub 2011 Nov 9.


Rutin Increases Muscle Mitochondrial Biogenesis with AMPK Activation in High-Fat Diet-Induced Obese Rats.

Seo S, Lee MS, Chang E, Shin Y, Oh S, Kim IH, Kim Y.

Nutrients. 2015 Sep 22;7(9):8152-69. doi: 10.3390/nu7095385.


Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle.

Cantó C, Jiang LQ, Deshmukh AS, Mataki C, Coste A, Lagouge M, Zierath JR, Auwerx J.

Cell Metab. 2010 Mar 3;11(3):213-9. doi: 10.1016/j.cmet.2010.02.006.

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