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Items: 1 to 20 of 125

1.

Down-regulation of insulin signaling is involved in painful diabetic neuropathy in type 2 diabetes.

Kou ZZ, Li CY, Tang J, Hu JC, Qu J, Liao YH, Wu SX, Li H, Li YQ.

Pain Physician. 2013 Mar-Apr;16(2):E71-83.

2.

JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat.

Dominguez E, Rivat C, Pommier B, Mauborgne A, Pohl M.

J Neurochem. 2008 Oct;107(1):50-60. doi: 10.1111/j.1471-4159.2008.05566.x. Epub 2008 Jul 12.

3.
4.

Phosphorylation of spinal N-methyl-d-aspartate receptor NR1 subunits by extracellular signal-regulated kinase in dorsal horn neurons and microglia contributes to diabetes-induced painful neuropathy.

Daulhac L, Maffre V, Mallet C, Etienne M, Privat AM, Kowalski-Chauvel A, Seva C, Fialip J, Eschalier A.

Eur J Pain. 2011 Feb;15(2):169.e1-169.e12. doi: 10.1016/j.ejpain.2010.06.003. Epub 2010 Jul 1.

PMID:
20594879
5.

STAT3 inhibitor WP1066 as a novel therapeutic agent for bCCI neuropathic pain rats.

Xue ZJ, Shen L, Wang ZY, Hui SY, Huang YG, Ma C.

Brain Res. 2014 Oct 2;1583:79-88. doi: 10.1016/j.brainres.2014.07.015. Epub 2014 Jul 30.

PMID:
25084036
6.

Aspirin-triggered Lipoxin A4 attenuates mechanical allodynia in association with inhibiting spinal JAK2/STAT3 signaling in neuropathic pain in rats.

Wang ZF, Li Q, Liu SB, Mi WL, Hu S, Zhao J, Tian Y, Mao-Ying QL, Jiang JW, Ma HJ, Wang YQ, Wu GC.

Neuroscience. 2014 Jul 25;273:65-78. doi: 10.1016/j.neuroscience.2014.04.052. Epub 2014 May 14.

PMID:
24836854
7.

Amyloid-β induces hepatic insulin resistance by activating JAK2/STAT3/SOCS-1 signaling pathway.

Zhang Y, Zhou B, Zhang F, Wu J, Hu Y, Liu Y, Zhai Q.

Diabetes. 2012 Jun;61(6):1434-43. doi: 10.2337/db11-0499. Epub 2012 Apr 20.

8.

[Effect of losartan on expression of Janus kinase 2 and signal transducer and activator of transcription 3 in glomeruli of diabetic rats].

Shi YH, Duan HJ, He N, Wang LH, Liu QJ, Gao F.

Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2005 Nov;17(11):662-6. Chinese.

9.

[Effects of JAK2/STAT3 signaling pathway on angiogenesis in non-small cell lung cancer].

Zhao M, Liu F, Wang JY, Zhang WY, Gao FH, Jiang B.

Zhonghua Yi Xue Za Zhi. 2011 Feb 15;91(6):375-81. Chinese.

PMID:
21418908
10.

Angiotensin II and endothelin-1 augment the vascular complications of diabetes via JAK2 activation.

Banes-Berceli AK, Ketsawatsomkron P, Ogbi S, Patel B, Pollock DM, Marrero MB.

Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H1291-9. Epub 2007 May 25.

11.

The leptin-deficient (ob/ob) mouse: a new animal model of peripheral neuropathy of type 2 diabetes and obesity.

Drel VR, Mashtalir N, Ilnytska O, Shin J, Li F, Lyzogubov VV, Obrosova IG.

Diabetes. 2006 Dec;55(12):3335-43.

12.

Involvement of microglial P2X7 receptors and downstream signaling pathways in long-term potentiation of spinal nociceptive responses.

Chu YX, Zhang Y, Zhang YQ, Zhao ZQ.

Brain Behav Immun. 2010 Oct;24(7):1176-89. doi: 10.1016/j.bbi.2010.06.001. Epub 2010 Jun 8.

PMID:
20554014
14.

Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII-CREB and Astroglial JAK2-STAT3 Cascades in Mice.

Liu S, Mi WL, Li Q, Zhang MT, Han P, Hu S, Mao-Ying QL, Wang YQ.

Anesthesiology. 2015 Nov;123(5):1154-69. doi: 10.1097/ALN.0000000000000850.

PMID:
26352378
15.

Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells.

Gao J, Tian J, Lv Y, Shi F, Kong F, Shi H, Zhao L.

Cancer Sci. 2009 Mar;100(3):389-95. doi: 10.1111/j.1349-7006.2008.01053.x. Epub 2008 Dec 16.

16.

Neuron-astrocyte signaling network in spinal cord dorsal horn mediates painful neuropathy of type 2 diabetes.

Dauch JR, Yanik BM, Hsieh W, Oh SS, Cheng HT.

Glia. 2012 Sep;60(9):1301-15. doi: 10.1002/glia.22349. Epub 2012 May 9.

17.

Reduced number, G protein coupling, and antinociceptive efficacy of spinal mu-opioid receptors in diabetic rats are reversed by nerve growth factor.

Shaqura M, Khalefa BI, Shakibaei M, Winkler J, Al-Khrasani M, Fürst S, Mousa SA, Schäfer M.

J Pain. 2013 Jul;14(7):720-30. doi: 10.1016/j.jpain.2013.01.776. Epub 2013 Apr 24.

PMID:
23623572
18.

Changes in serotoninergic and noradrenergic descending pain pathways during painful diabetic neuropathy: the preventive action of IGF1.

Morgado C, Silva L, Pereira-Terra P, Tavares I.

Neurobiol Dis. 2011 Jul;43(1):275-84. doi: 10.1016/j.nbd.2011.04.001. Epub 2011 Apr 15. Erratum in: Neurobiol Dis. 2012 Feb;45(2):829.

PMID:
21515376
19.

Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells.

Behera R, Kumar V, Lohite K, Karnik S, Kundu GC.

Carcinogenesis. 2010 Feb;31(2):192-200. doi: 10.1093/carcin/bgp289. Epub 2009 Nov 19.

PMID:
19926637
20.

Postconditioning inhibits myocardial apoptosis during prolonged reperfusion via a JAK2-STAT3-Bcl-2 pathway.

Tian Y, Zhang W, Xia D, Modi P, Liang D, Wei M.

J Biomed Sci. 2011 Aug 2;18:53. doi: 10.1186/1423-0127-18-53.

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