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Items: 1 to 20 of 97

1.

Pharmacologic inhibition of epigenetic modification reveals targets of aberrant promoter methylation in Ewing sarcoma.

Nestheide S, Bridge JA, Barnes M, Frayer R, Sumegi J.

Pediatr Blood Cancer. 2013 Sep;60(9):1437-46. doi: 10.1002/pbc.24526. Epub 2013 Mar 18.

PMID:
23508900
2.
3.

Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells.

Heller G, Schmidt WM, Ziegler B, Holzer S, Müllauer L, Bilban M, Zielinski CC, Drach J, Zöchbauer-Müller S.

Cancer Res. 2008 Jan 1;68(1):44-54. doi: 10.1158/0008-5472.CAN-07-2531.

4.
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Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2'-deoxycytidine.

Chen J, Röcken C, Klein-Hitpass L, Götze T, Leodolter A, Malfertheiner P, Ebert MP.

Clin Exp Metastasis. 2004;21(5):389-97.

PMID:
15672863
6.

Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle-cell lymphomas.

Ripperger T, von Neuhoff N, Kamphues K, Emura M, Lehmann U, Tauscher M, Schraders M, Groenen P, Skawran B, Rudolph C, Callet-Bauchu E, van Krieken JH, Schlegelberger B, Steinemann D.

Haematologica. 2007 Apr;92(4):460-8.

7.

Functional epigenetic approach identifies frequently methylated genes in Ewing sarcoma.

Alholle A, Brini AT, Gharanei S, Vaiyapuri S, Arrigoni E, Dallol A, Gentle D, Kishida T, Hiruma T, Avigad S, Grimer R, Maher ER, Latif F.

Epigenetics. 2013 Nov;8(11):1198-204. doi: 10.4161/epi.26266. Epub 2013 Sep 4.

PMID:
24005033
8.

Promoter Methylation Analysis Reveals That KCNA5 Ion Channel Silencing Supports Ewing Sarcoma Cell Proliferation.

Ryland KE, Hawkins AG, Weisenberger DJ, Punj V, Borinstein SC, Laird PW, Martens JR, Lawlor ER.

Mol Cancer Res. 2016 Jan;14(1):26-34. doi: 10.1158/1541-7786.MCR-15-0343. Epub 2015 Nov 16.

9.

Screening for epigenetically masked genes in colorectal cancer Using 5-Aza-2'-deoxycytidine, microarray and gene expression profile.

Khamas A, Ishikawa T, Shimokawa K, Mogushi K, Iida S, Ishiguro M, Mizushima H, Tanaka H, Uetake H, Sugihara K.

Cancer Genomics Proteomics. 2012 Mar-Apr;9(2):67-75.

PMID:
22399497
10.

Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma.

Rubinstein JC, Tran N, Ma S, Halaban R, Krauthammer M.

BMC Med Genomics. 2010 Feb 9;3:4. doi: 10.1186/1755-8794-3-4.

12.

Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma.

Kim TY, Zhong S, Fields CR, Kim JH, Robertson KD.

Cancer Res. 2006 Aug 1;66(15):7490-501.

13.

Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells.

Zhang C, Li H, Zhou G, Zhang Q, Zhang T, Li J, Zhang J, Hou J, Liew CT, Yin D.

J Pathol. 2007 Jun;212(2):134-42.

PMID:
17471463
14.

The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors.

Ying J, Srivastava G, Hsieh WS, Gao Z, Murray P, Liao SK, Ambinder R, Tao Q.

Clin Cancer Res. 2005 Sep 15;11(18):6442-9.

15.

Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma.

Tshuikina M, Jernberg-Wiklund H, Nilsson K, Oberg F.

Exp Hematol. 2008 Dec;36(12):1673-1681. doi: 10.1016/j.exphem.2008.08.001. Epub 2008 Oct 15.

PMID:
18922617
16.

Global demethylation of rat chondrosarcoma cells after treatment with 5-aza-2'-deoxycytidine results in increased tumorigenicity.

Hamm CA, Xie H, Costa FF, Vanin EF, Seftor EA, Sredni ST, Bischof J, Wang D, Bonaldo MF, Hendrix MJ, Soares MB.

PLoS One. 2009 Dec 17;4(12):e8340. doi: 10.1371/journal.pone.0008340.

17.

Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors.

Neumann O, Kesselmeier M, Geffers R, Pellegrino R, Radlwimmer B, Hoffmann K, Ehemann V, Schemmer P, Schirmacher P, Lorenzo Bermejo J, Longerich T.

Hepatology. 2012 Nov;56(5):1817-27. doi: 10.1002/hep.25870. Epub 2012 Oct 14.

PMID:
22689435
18.

Identification of GPX3 epigenetically silenced by CpG methylation in human esophageal squamous cell carcinoma.

He Y, Wang Y, Li P, Zhu S, Wang J, Zhang S.

Dig Dis Sci. 2011 Mar;56(3):681-8. doi: 10.1007/s10620-010-1369-0. Epub 2010 Aug 20.

PMID:
20725785
19.

Genome-wide analysis in a murine Dnmt1 knockdown model identifies epigenetically silenced genes in primary human pituitary tumors.

Dudley KJ, Revill K, Whitby P, Clayton RN, Farrell WE.

Mol Cancer Res. 2008 Oct;6(10):1567-74. doi: 10.1158/1541-7786.MCR-08-0234.

20.

Integrated epigenetics of human breast cancer: synoptic investigation of targeted genes, microRNAs and proteins upon demethylation treatment.

Radpour R, Barekati Z, Kohler C, Schumacher MM, Grussenmeyer T, Jenoe P, Hartmann N, Moes S, Letzkus M, Bitzer J, Lefkovits I, Staedtler F, Zhong XY.

PLoS One. 2011;6(11):e27355. doi: 10.1371/journal.pone.0027355. Epub 2011 Nov 4.

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