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Items: 1 to 20 of 105

1.

Ursodeoxycholic acid attenuates colonic epithelial secretory function.

Kelly OB, Mroz MS, Ward JB, Colliva C, Scharl M, Pellicciari R, Gilmer JF, Fallon PG, Hofmann AF, Roda A, Murray FE, Keely SJ.

J Physiol. 2013 May 1;591(9):2307-18. doi: 10.1113/jphysiol.2013.252544. Epub 2013 Mar 18.

2.

Ursodeoxycholic acid and lithocholic acid exert anti-inflammatory actions in the colon.

Ward JBJ, Lajczak NK, Kelly OB, O'Dwyer AM, Giddam AK, Ní Gabhann J, Franco P, Tambuwala MM, Jefferies CA, Keely S, Roda A, Keely SJ.

Am J Physiol Gastrointest Liver Physiol. 2017 Jun 1;312(6):G550-G558. doi: 10.1152/ajpgi.00256.2016. Epub 2017 Mar 30.

PMID:
28360029
3.

Lithocholic acid attenuates cAMP-dependent Cl- secretion in human colonic epithelial T84 cells.

Ao M, Domingue JC, Khan N, Javed F, Osmani K, Sarathy J, Rao MC.

Am J Physiol Cell Physiol. 2016 Jun 1;310(11):C1010-23. doi: 10.1152/ajpcell.00350.2015. Epub 2016 Apr 13.

4.

Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo.

Mroz MS, Keating N, Ward JB, Sarker R, Amu S, Aviello G, Donowitz M, Fallon PG, Keely SJ.

Gut. 2014 May;63(5):808-17. doi: 10.1136/gutjnl-2013-305088. Epub 2013 Aug 5.

PMID:
23916961
5.

Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells.

Keating N, Mroz MS, Scharl MM, Marsh C, Ferguson G, Hofmann AF, Keely SJ.

J Cell Mol Med. 2009 Aug;13(8B):2293-303. doi: 10.1111/j.1582-4934.2009.00838.x. Epub 2009 Jul 6.

6.

Hydroxylase inhibition attenuates colonic epithelial secretory function and ameliorates experimental diarrhea.

Ward JB, Lawler K, Amu S, Taylor CT, Fallon PG, Keely SJ.

FASEB J. 2011 Feb;25(2):535-43. doi: 10.1096/fj.10-166983. Epub 2010 Oct 13.

PMID:
20944011
7.

Ursodeoxycholic acid and cholesterol induce enterohepatic cycling of bilirubin in rodents.

Méndez-Sánchez N, Brink MA, Paigen B, Carey MC.

Gastroenterology. 1998 Sep;115(3):722-32.

PMID:
9721170
8.

JNK mitogen-activated protein kinase limits calcium-dependent chloride secretion across colonic epithelial cells.

Donnellan F, Keating N, Geoghegan P, Murray FE, Harvey BJ, Keely SJ.

Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G37-44. doi: 10.1152/ajpgi.00202.2009. Epub 2009 Oct 29.

9.

A novel, protective role of ursodeoxycholate in bile-induced pancreatic ductal injury.

Katona M, Hegyi P, Kui B, Balla Z, Rakonczay Z Jr, Rázga Z, Tiszlavicz L, Maléth J, Venglovecz V.

Am J Physiol Gastrointest Liver Physiol. 2016 Feb 1;310(3):G193-204. doi: 10.1152/ajpgi.00317.2015. Epub 2015 Nov 25.

10.

Levamisole inhibits intestinal Cl- secretion via basolateral K+ channel blockade.

Mun EC, Mayol JM, Riegler M, O'Brien TC, Farokhzad OC, Song JC, Pothoulakis C, Hrnjez BJ, Matthews JB.

Gastroenterology. 1998 Jun;114(6):1257-67.

PMID:
9609763
11.
12.

Biliary bile acids in primary biliary cirrhosis: effect of ursodeoxycholic acid.

Combes B, Carithers RL Jr, Maddrey WC, Munoz S, Garcia-Tsao G, Bonner GF, Boyer JL, Luketic VA, Shiffman ML, Peters MG, White H, Zetterman RK, Risser R, Rossi SS, Hofmann AF.

Hepatology. 1999 Jun;29(6):1649-54.

13.
15.

Permeation enhancement of octreotide by specific bile salts in rats and human subjects: in vitro, in vivo correlations.

Fricker G, Fahr A, Beglinger C, Kissel T, Reiter G, Drewe J.

Br J Pharmacol. 1996 Jan;117(1):217-23.

16.

Changes in bile acid composition and effect on cytolytic activity of fecal water by ursodeoxycholic acid administration: a placebo-controlled cross-over intervention trial in healthy volunteers.

van Gorkom BA, van der Meer R, Boersma-van Ek W, Termont DS, de Vries EG, Kleibeuker JH.

Scand J Gastroenterol. 2002 Aug;37(8):965-71.

PMID:
12229974
17.

Protective effects of ursodeoxycholic acid on chenodeoxycholic acid-induced liver injury in hamsters.

Iwaki T, Ishizaki K, Kinoshita S, Tanaka H, Fukunari A, Tsurufuji M, Imada T.

World J Gastroenterol. 2007 Oct 7;13(37):5003-8.

18.

Hydrophilic but not hydrophobic bile acids prevent gallbladder muscle dysfunction in acute cholecystitis.

Xiao ZL, Biancani P, Carey MC, Behar J.

Hepatology. 2003 Jun;37(6):1442-50.

PMID:
12774024
19.
20.

Anti-diarrheal mechanism of the traditional remedy Uzara via reduction of active chloride secretion.

Schulzke JD, Andres S, Amasheh M, Fromm A, Günzel D.

PLoS One. 2011 Mar 30;6(3):e18107. doi: 10.1371/journal.pone.0018107.

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