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Items: 1 to 20 of 94

1.

The HBx protein of hepatitis B virus confers resistance against nucleolar stress and anti-cancer drug-induced p53 expression.

Kapoor NR, Ahuja R, Shukla SK, Kumar V.

FEBS Lett. 2013 May 2;587(9):1287-92. doi: 10.1016/j.febslet.2013.03.004. Epub 2013 Mar 16.

2.

Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress.

Bursać S, Brdovčak MC, Pfannkuchen M, Orsolić I, Golomb L, Zhu Y, Katz C, Daftuar L, Grabušić K, Vukelić I, Filić V, Oren M, Prives C, Volarevic S.

Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20467-72. doi: 10.1073/pnas.1218535109. Epub 2012 Nov 20.

3.

mTOR inhibitors blunt the p53 response to nucleolar stress by regulating RPL11 and MDM2 levels.

Goudarzi KM, Nistér M, Lindström MS.

Cancer Biol Ther. 2014;15(11):1499-514. doi: 10.4161/15384047.2014.955743.

4.

Sorafenib overcomes the chemoresistance in HBx-expressing hepatocellular carcinoma cells through down-regulation of HBx protein stability and suppresses HBV gene expression.

Kim HY, Jung HU, Yoo SH, Yoo KS, Cheong J, Park BS, Yun I, Yoo YH.

Cancer Lett. 2014 Dec 1;355(1):61-9. doi: 10.1016/j.canlet.2014.09.015. Epub 2014 Sep 11.

PMID:
25218348
5.

Hepatitis B virus X protein mutants exhibit distinct biological activities in hepatoma Huh7 cells.

Liu X, Zhang S, Lin J, Zhang S, Feitelson MA, Gao H, Zhu M.

Biochem Biophys Res Commun. 2008 Sep 5;373(4):643-7. doi: 10.1016/j.bbrc.2008.06.087. Epub 2008 Jul 3.

PMID:
18602370
6.

Truncated HBx-dependent silencing of GAS2 promotes hepatocarcinogenesis through deregulation of cell cycle, senescence and p53-mediated apoptosis.

Zhu R, Mok MT, Kang W, Lau SS, Yip WK, Chen Y, Lai PB, Wong VW, To KF, Sung JJ, Cheng AS, Chan HL.

J Pathol. 2015 Sep;237(1):38-49. doi: 10.1002/path.4554. Epub 2015 May 28.

PMID:
25925944
7.

Regulation of nucleolar signalling to p53 through NEDDylation of L11.

Sundqvist A, Liu G, Mirsaliotis A, Xirodimas DP.

EMBO Rep. 2009 Oct;10(10):1132-9. doi: 10.1038/embor.2009.178. Epub 2009 Aug 28.

8.

Perturbation of 60 S ribosomal biogenesis results in ribosomal protein L5- and L11-dependent p53 activation.

Sun XX, Wang YG, Xirodimas DP, Dai MS.

J Biol Chem. 2010 Aug 13;285(33):25812-21. doi: 10.1074/jbc.M109.098442. Epub 2010 Jun 16.

9.

p53 Promotes proteasome-dependent degradation of oncogenic protein HBx by transcription of MDM2.

Xian L, Zhao J, Wang J, Fang Z, Peng B, Wang W, Ji X, Yu L.

Mol Biol Rep. 2010 Jul;37(6):2935-40. doi: 10.1007/s11033-009-9855-1. Epub 2009 Oct 16.

PMID:
19842060
10.
11.

Hepatitis B virus X protein modulates oncogene Yes-associated protein by CREB to promote growth of hepatoma cells.

Zhang T, Zhang J, You X, Liu Q, Du Y, Gao Y, Shan C, Kong G, Wang Y, Yang X, Ye L, Zhang X.

Hepatology. 2012 Dec;56(6):2051-9. doi: 10.1002/hep.25899. Epub 2012 Nov 13.

PMID:
22707013
13.

Recruitment of RPL11 at promoter sites of p53-regulated genes upon nucleolar stress through NEDD8 and in an Mdm2-dependent manner.

Mahata B, Sundqvist A, Xirodimas DP.

Oncogene. 2012 Jun 21;31(25):3060-71. doi: 10.1038/onc.2011.482. Epub 2011 Nov 14.

PMID:
22081073
15.

Hepatitis B virus X induces cell proliferation in the hepatocarcinogenesis via up-regulation of cytoplasmic p21 expression.

Yano M, Ohkoshi S, Aoki YH, Takahashi H, Kurita S, Yamazaki K, Suzuki K, Yamagiwa S, Sanpei A, Fujimaki S, Wakai T, Kudo SE, Matsuda Y, Aoyagi Y.

Liver Int. 2013 Sep;33(8):1218-29. doi: 10.1111/liv.12176. Epub 2013 Apr 17.

PMID:
23590292
16.

Altered binding site selection of p53 transcription cassettes by hepatitis B virus X protein.

Chan C, Wang Y, Chow PK, Chung AY, Ooi LL, Lee CG.

Mol Cell Biol. 2013 Feb;33(3):485-97. doi: 10.1128/MCB.01189-12. Epub 2012 Nov 12.

17.

HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma.

Huang JL, Ren TY, Cao SW, Zheng SH, Hu XM, Hu YW, Lin L, Chen J, Zheng L, Wang Q.

Oncotarget. 2015 Oct 20;6(32):33791-804. doi: 10.18632/oncotarget.5667.

18.

Hepatitis B virus X protein upregulates HSP90alpha expression via activation of c-Myc in human hepatocarcinoma cell line, HepG2.

Li W, Miao X, Qi Z, Zeng W, Liang J, Liang Z.

Virol J. 2010 Feb 20;7:45. doi: 10.1186/1743-422X-7-45.

19.

Dual effects of hepatitis B virus X protein on the regulation of cell-cycle control depending on the status of cellular p53.

Ahn JY, Jung EY, Kwun HJ, Lee CW, Sung YC, Jang KL.

J Gen Virol. 2002 Nov;83(Pt 11):2765-72.

PMID:
12388812
20.

Identification of ribosomal protein S25 (RPS25)-MDM2-p53 regulatory feedback loop.

Zhang X, Wang W, Wang H, Wang MH, Xu W, Zhang R.

Oncogene. 2013 May 30;32(22):2782-91. doi: 10.1038/onc.2012.289. Epub 2012 Jul 9.

PMID:
22777350

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