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Down-regulation of amygdala and insula functional circuits by varenicline and nicotine in abstinent cigarette smokers.

Sutherland MT, Carroll AJ, Salmeron BJ, Ross TJ, Hong LE, Stein EA.

Biol Psychiatry. 2013 Oct 1;74(7):538-46. doi: 10.1016/j.biopsych.2013.01.035. Epub 2013 Mar 15.


Individual differences in amygdala reactivity following nicotinic receptor stimulation in abstinent smokers.

Sutherland MT, Carroll AJ, Salmeron BJ, Ross TJ, Hong LE, Stein EA.

Neuroimage. 2013 Feb 1;66:585-93. doi: 10.1016/j.neuroimage.2012.10.043. Epub 2012 Oct 27.


Effects of the alpha4beta2 partial agonist varenicline on brain activity and working memory in abstinent smokers.

Loughead J, Ray R, Wileyto EP, Ruparel K, Sanborn P, Siegel S, Gur RC, Lerman C.

Biol Psychiatry. 2010 Apr 15;67(8):715-21. doi: 10.1016/j.biopsych.2010.01.016. Epub 2010 Mar 6.


Neural Signatures of Cognitive Flexibility and Reward Sensitivity Following Nicotinic Receptor Stimulation in Dependent Smokers: A Randomized Trial.

Lesage E, Aronson SE, Sutherland MT, Ross TJ, Salmeron BJ, Stein EA.

JAMA Psychiatry. 2017 Jun 1;74(6):632-640. doi: 10.1001/jamapsychiatry.2017.0400.


Brain activity and emotional processing in smokers treated with varenicline.

Loughead J, Ray R, Wileyto EP, Ruparel K, O'Donnell GP, Senecal N, Siegel S, Gur RC, Lerman C.

Addict Biol. 2013 Jul;18(4):732-8. doi: 10.1111/j.1369-1600.2011.00324.x. Epub 2011 Apr 20.


Insula's functional connectivity with ventromedial prefrontal cortex mediates the impact of trait alexithymia on state tobacco craving.

Sutherland MT, Carroll AJ, Salmeron BJ, Ross TJ, Stein EA.

Psychopharmacology (Berl). 2013 Jul;228(1):143-55. doi: 10.1007/s00213-013-3018-8. Epub 2013 Feb 28.


Divergent functional effects of sazetidine-a and varenicline during nicotine withdrawal.

Turner JR, Wilkinson DS, Poole RL, Gould TJ, Carlson GC, Blendy JA.

Neuropsychopharmacology. 2013 Sep;38(10):2035-47. doi: 10.1038/npp.2013.105. Epub 2013 Apr 29.


Insular and anterior cingulate circuits in smokers with schizophrenia.

Moran LV, Sampath H, Stein EA, Hong LE.

Schizophr Res. 2012 Dec;142(1-3):223-9. doi: 10.1016/j.schres.2012.08.033. Epub 2012 Sep 27.


Efficacy and tolerability of pharmacotherapies to aid smoking cessation in adolescents.

Bailey SR, Crew EE, Riske EC, Ammerman S, Robinson TN, Killen JD.

Paediatr Drugs. 2012 Apr 1;14(2):91-108. doi: 10.2165/11594370-000000000-00000. Review.


Effect of varenicline and bupropion SR on craving, nicotine withdrawal symptoms, and rewarding effects of smoking during a quit attempt.

West R, Baker CL, Cappelleri JC, Bushmakin AG.

Psychopharmacology (Berl). 2008 Apr;197(3):371-7. Epub 2007 Dec 15.


Combining varenicline and nicotine patches: a randomized controlled trial study in smoking cessation.

Ramon JM, Morchon S, Baena A, Masuet-Aumatell C.

BMC Med. 2014 Oct 8;12:172. doi: 10.1186/s12916-014-0172-8.


Reward Anticipation Is Differentially Modulated by Varenicline and Nicotine in Smokers.

Fedota JR, Sutherland MT, Salmeron BJ, Ross TJ, Hong LE, Stein EA.

Neuropsychopharmacology. 2015 Jul;40(8):2038-46. doi: 10.1038/npp.2015.54. Epub 2015 Mar 6.


Effects of varenicline on smoking cue–triggered neural and craving responses.

Franklin T, Wang Z, Suh JJ, Hazan R, Cruz J, Li Y, Goldman M, Detre JA, O'Brien CP, Childress AR.

Arch Gen Psychiatry. 2011 May;68(5):516-26. doi: 10.1001/archgenpsychiatry.2010.190. Epub 2011 Jan 3.


Pharmacokinetic-pharmacodynamic modeling of the effect of varenicline on nicotine craving in adult smokers.

Ravva P, Gastonguay MR, Faessel HM, Lee TC, Niaura R.

Nicotine Tob Res. 2015 Jan;17(1):106-13. doi: 10.1093/ntr/ntu154. Epub 2014 Aug 21.


The efficacy and safety of a nicotine conjugate vaccine (NicVAX®) or placebo co-administered with varenicline (Champix®) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial.

Hoogsteder PH, Kotz D, van Spiegel PI, Viechtbauer W, Brauer R, Kessler PD, Kalnik MW, Fahim RE, van Schayck OC.

BMC Public Health. 2012 Dec 6;12:1052. doi: 10.1186/1471-2458-12-1052.


A comparison of brain and behavioral effects of varenicline and nicotine in rats.

King J, Huang W, Chen W, Heffernan M, Shields J, Rane P, Bircher R, DiFranza JR.

Behav Brain Res. 2011 Sep 30;223(1):42-7. doi: 10.1016/j.bbr.2011.04.012. Epub 2011 Apr 17.


Combination treatment with varenicline and bupropion in an adaptive smoking cessation paradigm.

Rose JE, Behm FM.

Am J Psychiatry. 2014 Nov 1;171(11):1199-205. doi: 10.1176/appi.ajp.2014.13050595.


Varenicline improves mood and cognition during smoking abstinence.

Patterson F, Jepson C, Strasser AA, Loughead J, Perkins KA, Gur RC, Frey JM, Siegel S, Lerman C.

Biol Psychiatry. 2009 Jan 15;65(2):144-9. doi: 10.1016/j.biopsych.2008.08.028. Epub 2008 Oct 8.


Effects of varenicline and bupropion sustained-release use plus intensive smoking cessation counseling on prolonged abstinence from smoking and on depression, negative affect, and other symptoms of nicotine withdrawal.

Cinciripini PM, Robinson JD, Karam-Hage M, Minnix JA, Lam C, Versace F, Brown VL, Engelmann JM, Wetter DW.

JAMA Psychiatry. 2013 May;70(5):522-33. doi: 10.1001/jamapsychiatry.2013.678.

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