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Measurements of the impact of 3' end sequences on gene expression reveal wide range and sequence dependent effects.

Shalem O, Carey L, Zeevi D, Sharon E, Keren L, Weinberger A, Dahan O, Pilpel Y, Segal E.

PLoS Comput Biol. 2013;9(3):e1002934. doi: 10.1371/journal.pcbi.1002934. Epub 2013 Mar 7.


DNA damage induces targeted, genome-wide variation of poly(A) sites in budding yeast.

Graber JH, Nazeer FI, Yeh PC, Kuehner JN, Borikar S, Hoskinson D, Moore CL.

Genome Res. 2013 Oct;23(10):1690-703. doi: 10.1101/gr.144964.112. Epub 2013 Jun 20.


Species-specific factors mediate extensive heterogeneity of mRNA 3' ends in yeasts.

Moqtaderi Z, Geisberg JV, Jin Y, Fan X, Struhl K.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11073-8. doi: 10.1073/pnas.1309384110. Epub 2013 Jun 17.


Systematic dissection of the sequence determinants of gene 3' end mediated expression control.

Shalem O, Sharon E, Lubliner S, Regev I, Lotan-Pompan M, Yakhini Z, Segal E.

PLoS Genet. 2015 Apr 15;11(4):e1005147. doi: 10.1371/journal.pgen.1005147. eCollection 2015 Apr.


Implications of polyadenylation in health and disease.

Curinha A, Oliveira Braz S, Pereira-Castro I, Cruz A, Moreira A.

Nucleus. 2014;5(6):508-19. doi: 10.4161/nucl.36360. Epub 2014 Oct 31. Review.


Expression analysis of RNA14, a gene involved in mRNA 3' end maturation in yeast: characterization of the rna14-5 mutant strain.

Brendolise C, Rouillard JM, Dufour ME, Lacroute F.

Mol Genet Genomics. 2002 Jun;267(4):515-25. Epub 2002 May 23.


The yeast FBP1 poly(A) signal functions in both orientations and overlaps with a gene promoter.

Aranda A, Pérez-Ortín JE, Moore C, del Olmo M.

Nucleic Acids Res. 1998 Oct 15;26(20):4588-96.


Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3'-End Formation in the Failing Human Heart.

Creemers EE, Bawazeer A, Ugalde AP, van Deutekom HW, van der Made I, de Groot NE, Adriaens ME, Cook SA, Bezzina CR, Hubner N, van der Velden J, Elkon R, Agami R, Pinto YM.

Circ Res. 2016 Feb 5;118(3):433-8. doi: 10.1161/CIRCRESAHA.115.307082. Epub 2015 Dec 15. Erratum in: Circ Res. 2016 Oct 14;119(9):e139.


G20210A is a functional mutation in the prothrombin gene; effect on protein levels and 3'-end formation.

Ceelie H, Spaargaren-van Riel CC, Bertina RM, Vos HL.

J Thromb Haemost. 2004 Jan;2(1):119-27.


Transcript features alone enable accurate prediction and understanding of gene expression in S. cerevisiae.

Zur H, Tuller T.

BMC Bioinformatics. 2013;14 Suppl 15:S1. doi: 10.1186/1471-2105-14-S15-S1. Epub 2013 Oct 15.


Flexibility and interchangeability of polyadenylation signals in Saccharomyces cerevisiae.

Heidmann S, Schindewolf C, Stumpf G, Domdey H.

Mol Cell Biol. 1994 Jul;14(7):4633-42.


3'-End processing of pre-mRNA in eukaryotes.

Wahle E, Rüegsegger U.

FEMS Microbiol Rev. 1999 Jun;23(3):277-95. Review.


Point mutations upstream of the yeast ADH2 poly(A) site significantly reduce the efficiency of 3'-end formation.

Hyman LE, Seiler SH, Whoriskey J, Moore CL.

Mol Cell Biol. 1991 Apr;11(4):2004-12.


Genome-wide polyadenylation site mapping.

Pelechano V, Wilkening S, Järvelin AI, Tekkedil MM, Steinmetz LM.

Methods Enzymol. 2012;513:271-96. doi: 10.1016/B978-0-12-391938-0.00012-4.


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