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Items: 1 to 20 of 115

1.

[Expression of 5-lipoxygenase in hippocampal CA1 neuronal damage following global cerebral ischemia in rats].

Chen W, Li C, Zhao J, Zhang X, Han H, Wei E, Zhang L.

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013 Jan;42(1):61-6. Chinese.

PMID:
23505109
2.

5-lipoxygenase inhibitor zileuton attenuates ischemic brain damage: involvement of matrix metalloproteinase 9.

Tu XK, Yang WZ, Shi SS, Chen CM, Wang CH.

Neurol Res. 2009 Oct;31(8):848-52. doi: 10.1179/174313209X403913. Epub 2009 Mar 23.

PMID:
19309543
3.

5-LOX Inhibitor Zileuton Reduces Inflammatory Reaction and Ischemic Brain Damage Through the Activation of PI3K/Akt Signaling Pathway.

Tu XK, Zhang HB, Shi SS, Liang RS, Wang CH, Chen CM, Yang WZ.

Neurochem Res. 2016 Oct;41(10):2779-2787. Epub 2016 Jul 5.

PMID:
27380038
4.

5-Lipoxygenase inhibitor zileuton inhibits neuronal apoptosis following focal cerebral ischemia.

Shi SS, Yang WZ, Tu XK, Wang CH, Chen CM, Chen Y.

Inflammation. 2013 Dec;36(6):1209-17. doi: 10.1007/s10753-013-9657-4.

PMID:
23695166
5.

Zileuton reduces inflammatory reaction and brain damage following permanent cerebral ischemia in rats.

Tu XK, Yang WZ, Wang CH, Shi SS, Zhang YL, Chen CM, Yang YK, Jin CD, Wen S.

Inflammation. 2010 Oct;33(5):344-52. doi: 10.1007/s10753-010-9191-6.

PMID:
20204486
6.

[5-lipoxygenase is involved in rotenone-induced injury in PC12 cells].

Zhang XY, Zhang LH, Li CT, Chen WJ, Zhao JB, Wei EQ.

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2011 Mar;40(2):150-5. Chinese.

PMID:
21488210
7.

Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton.

Patel NS, Cuzzocrea S, Chatterjee PK, Di Paola R, Sautebin L, Britti D, Thiemermann C.

Mol Pharmacol. 2004 Aug;66(2):220-7.

8.

Reduction of the multiple organ injury and dysfunction caused by endotoxemia in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton.

Collin M, Rossi A, Cuzzocrea S, Patel NS, Di Paola R, Hadley J, Collino M, Sautebin L, Thiemermann C.

J Leukoc Biol. 2004 Nov;76(5):961-70. Epub 2004 Aug 24.

PMID:
15328337
9.

Time-Course Change of Redd1 Expressions in the Hippocampal CA1 Region Following Chronic Cerebral Hypoperfusion.

Park JA, Lee CH.

Cell Mol Neurobiol. 2017 Apr;37(3):563-569. doi: 10.1007/s10571-016-0385-9. Epub 2016 May 27.

PMID:
27233899
10.
11.

[Influence on the expression of RHOA and ROCK-II after global cerebral ischemia-reperfusion in hippocampus by shenxiong huayu capsule].

Huang HL, Li JM, Zhao YN, Ma RL, Niu J, Chen GZ.

Sichuan Da Xue Xue Bao Yi Xue Ban. 2015 Jan;46(1):51-6. Chinese.

PMID:
25807796
12.

The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis.

Liu Y, Wang W, Li Y, Xiao Y, Cheng J, Jia J.

Biol Pharm Bull. 2015;38(8):1234-9. doi: 10.1248/bpb.b15-00048.

13.
14.

5-Lipoxygenase contributes to the progression of hepatocellular carcinoma.

Xu XM, Deng JJ, Yuan GJ, Yang F, Guo HT, Xiang M, Ge W, Wu YG.

Mol Med Rep. 2011 Nov-Dec;4(6):1195-200. doi: 10.3892/mmr.2011.547. Epub 2011 Aug 8.

PMID:
21833474
15.

Targeting type-2 metabotropic glutamate receptors to protect vulnerable hippocampal neurons against ischemic damage.

Motolese M, Mastroiacovo F, Cannella M, Bucci D, Gaglione A, Riozzi B, Lütjens R, Poli SM, Celanire S, Bruno V, Battaglia G, Nicoletti F.

Mol Brain. 2015 Oct 24;8(1):66. doi: 10.1186/s13041-015-0158-2.

16.

A rat air pouch model for evaluating the efficacy and selectivity of 5-lipoxygenase inhibitors.

Zweifel BS, Hardy MM, Anderson GD, Dufield DR, Pufahl RA, Masferrer JL.

Eur J Pharmacol. 2008 Apr 14;584(1):166-74. doi: 10.1016/j.ejphar.2008.01.021. Epub 2008 Feb 5.

PMID:
18295198
17.

Severe global cerebral ischemia-induced programmed necrosis of hippocampal CA1 neurons in rat is prevented by 3-methyladenine: a widely used inhibitor of autophagy.

Wang JY, Xia Q, Chu KT, Pan J, Sun LN, Zeng B, Zhu YJ, Wang Q, Wang K, Luo BY.

J Neuropathol Exp Neurol. 2011 Apr;70(4):314-22. doi: 10.1097/NEN.0b013e31821352bd.

PMID:
21412169
18.

Oxygen-glucose deprivation activates 5-lipoxygenase mediated by oxidative stress through the p38 mitogen-activated protein kinase pathway in PC12 cells.

Li CT, Zhang WP, Lu YB, Fang SH, Yuan YM, Qi LL, Zhang LH, Huang XJ, Zhang L, Chen Z, Wei EQ.

J Neurosci Res. 2009 Mar;87(4):991-1001. doi: 10.1002/jnr.21913.

PMID:
18951527
19.

Attenuation of mitochondrial and nuclear p38α signaling: a novel mechanism of estrogen neuroprotection in cerebral ischemia.

Han D, Scott EL, Dong Y, Raz L, Wang R, Zhang Q.

Mol Cell Endocrinol. 2015 Jan 15;400:21-31. doi: 10.1016/j.mce.2014.11.010. Epub 2014 Nov 25.

PMID:
25462588
20.

Comparison of different quantification methods to determine hippocampal damage after cerebral ischemia.

Wang J, Jahn-Eimermacher A, Brückner M, Werner C, Engelhard K, Thal SC.

J Neurosci Methods. 2015 Jan 30;240:67-76. doi: 10.1016/j.jneumeth.2014.11.001. Epub 2014 Nov 8.

PMID:
25445060

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