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Items: 1 to 20 of 101

1.

The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis.

Wang AH, Zare H, Mousavi K, Wang C, Moravec CE, Sirotkin HI, Ge K, Gutierrez-Cruz G, Sartorelli V.

EMBO J. 2013 Apr 17;32(8):1075-86. doi: 10.1038/emboj.2013.54. Epub 2013 Mar 15.

2.

UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis.

Seenundun S, Rampalli S, Liu QC, Aziz A, Palii C, Hong S, Blais A, Brand M, Ge K, Dilworth FJ.

EMBO J. 2010 Apr 21;29(8):1401-11. doi: 10.1038/emboj.2010.37. Epub 2010 Mar 18.

3.

The Histone Demethylase UTX Promotes Brown Adipocyte Thermogenic Program Via Coordinated Regulation of H3K27 Demethylation and Acetylation.

Zha L, Li F, Wu R, Artinian L, Rehder V, Yu L, Liang H, Xue B, Shi H.

J Biol Chem. 2015 Oct 9;290(41):25151-63. doi: 10.1074/jbc.M115.662650. Epub 2015 Aug 25.

4.

The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins.

Wang AH, Juan AH, Ko KD, Tsai PF, Zare H, Dell'Orso S, Sartorelli V.

Mol Cell. 2017 Oct 19;68(2):398-413.e6. doi: 10.1016/j.molcel.2017.09.016. Epub 2017 Oct 12.

PMID:
29033324
5.

Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo.

Dal-Pra S, Hodgkinson CP, Mirotsou M, Kirste I, Dzau VJ.

Circ Res. 2017 Apr 28;120(9):1403-1413. doi: 10.1161/CIRCRESAHA.116.308741. Epub 2017 Feb 16.

PMID:
28209718
6.

Histone demethylase Utx regulates differentiation and mineralization in osteoblasts.

Yang D, Okamura H, Teramachi J, Haneji T.

J Cell Biochem. 2015 Nov;116(11):2628-36. doi: 10.1002/jcb.25210.

PMID:
25920016
7.

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.

Agger K, Cloos PA, Christensen J, Pasini D, Rose S, Rappsilber J, Issaeva I, Canaani E, Salcini AE, Helin K.

Nature. 2007 Oct 11;449(7163):731-4. Epub 2007 Aug 22.

PMID:
17713478
8.

KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development.

Shpargel KB, Starmer J, Yee D, Pohlers M, Magnuson T.

PLoS Genet. 2014 Aug 7;10(8):e1004507. doi: 10.1371/journal.pgen.1004507. eCollection 2014 Aug.

9.

The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner.

Maures TJ, Greer EL, Hauswirth AG, Brunet A.

Aging Cell. 2011 Dec;10(6):980-90. doi: 10.1111/j.1474-9726.2011.00738.x. Epub 2011 Sep 16.

10.

Genome-wide association between Six4, MyoD, and the histone demethylase Utx during myogenesis.

Chakroun I, Yang D, Girgis J, Gunasekharan A, Phenix H, Kærn M, Blais A.

FASEB J. 2015 Nov;29(11):4738-55. doi: 10.1096/fj.15-277053. Epub 2015 Jul 30.

11.

UTX demethylase activity is required for satellite cell-mediated muscle regeneration.

Faralli H, Wang C, Nakka K, Benyoucef A, Sebastian S, Zhuang L, Chu A, Palii CG, Liu C, Camellato B, Brand M, Ge K, Dilworth FJ.

J Clin Invest. 2016 Apr 1;126(4):1555-65. doi: 10.1172/JCI83239. Epub 2016 Mar 21.

12.

Histone demethylation maintains Prdm14 and Tsix expression and represses xIst in embryonic stem cells.

Kamikawa YF, Donohoe ME.

PLoS One. 2015 May 20;10(5):e0125626. doi: 10.1371/journal.pone.0125626. eCollection 2015.

13.

A histone H3 lysine 27 demethylase regulates animal posterior development.

Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, Iwase S, Alpatov R, Issaeva I, Canaani E, Roberts TM, Chang HY, Shi Y.

Nature. 2007 Oct 11;449(7163):689-94. Epub 2007 Sep 12.

PMID:
17851529
14.

Histone demethylases Kdm6ba and Kdm6bb redundantly promote cardiomyocyte proliferation during zebrafish heart ventricle maturation.

Akerberg AA, Henner A, Stewart S, Stankunas K.

Dev Biol. 2017 Jun 1;426(1):84-96. doi: 10.1016/j.ydbio.2017.03.030. Epub 2017 Apr 1.

PMID:
28372944
15.

LSD1 Controls Timely MyoD Expression via MyoD Core Enhancer Transcription.

Scionti I, Hayashi S, Mouradian S, Girard E, Esteves de Lima J, Morel V, Simonet T, Wurmser M, Maire P, Ancelin K, Metzger E, Schüle R, Goillot E, Relaix F, Schaeffer L.

Cell Rep. 2017 Feb 21;18(8):1996-2006. doi: 10.1016/j.celrep.2017.01.078.

16.

Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A.

Sengoku T, Yokoyama S.

Genes Dev. 2011 Nov 1;25(21):2266-77. doi: 10.1101/gad.172296.111. Epub 2011 Oct 14.

17.

UTX-1 regulates Tat-induced HIV-1 transactivation via changing the methylated status of histone H3.

Zhang HS, Du GY, Liu Y, Zhang ZG, Zhou Z, Li H, Dai KQ, Yu XY, Gou XM.

Int J Biochem Cell Biol. 2016 Nov;80:51-56. doi: 10.1016/j.biocel.2016.09.016. Epub 2016 Sep 23.

PMID:
27671333
18.

Chromatin states of developmentally-regulated genes revealed by DNA and histone methylation patterns in zebrafish embryos.

Lindeman LC, Winata CL, Aanes H, Mathavan S, Alestrom P, Collas P.

Int J Dev Biol. 2010;54(5):803-13. doi: 10.1387/ijdb.103081ll.

19.

The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation.

Chen S, Ma J, Wu F, Xiong LJ, Ma H, Xu W, Lv R, Li X, Villen J, Gygi SP, Liu XS, Shi Y.

Genes Dev. 2012 Jun 15;26(12):1364-75. doi: 10.1101/gad.186056.111.

20.

The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation.

Yoh SM, Lucas JS, Jones KA.

Genes Dev. 2008 Dec 15;22(24):3422-34. doi: 10.1101/gad.1720008.

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