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Items: 1 to 20 of 587

1.

Synthesis and anticancer activity of novel 2-pyridyl hexahyrocyclooctathieno[2,3-d]pyrimidine derivatives.

Kassab AE, Gedawy EM.

Eur J Med Chem. 2013 May;63:224-30. doi: 10.1016/j.ejmech.2013.02.011. Epub 2013 Feb 19.

PMID:
23501108
2.

Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo[4,3-c]pyrimidine derivatives.

Kandeel MM, Refaat HM, Kassab AE, Shahin IG, Abdelghany TM.

Eur J Med Chem. 2015 Jan 27;90:620-32. doi: 10.1016/j.ejmech.2014.12.009. Epub 2014 Dec 6.

PMID:
25499930
3.

Anticancer activities of some newly synthesized pyridine, pyrane, and pyrimidine derivatives.

Amr AG, Mohamed AM, Mohamed SF, Abdel-Hafez NA, Hammam Ael-F.

Bioorg Med Chem. 2006 Aug 15;14(16):5481-8. Epub 2006 May 18.

PMID:
16713269
4.

Anticancer activities of some newly synthesized pyrazole and pyrimidine derivatives.

Mohamed AM, El-Sayed WA, Alsharari MA, Al-Qalawi HR, Germoush MO.

Arch Pharm Res. 2013 Sep;36(9):1055-65. doi: 10.1007/s12272-013-0163-x. Epub 2013 Jun 5.

PMID:
23737106
5.

Induction of intrinsic apoptosis pathway in colon cancer HCT-116 cells by novel 2-substituted-5,6,7,8-tetrahydronaphthalene derivatives.

Gamal-Eldeen AM, Hamdy NA, Abdel-Aziz HA, El-Hussieny EA, Fakhr IM.

Eur J Med Chem. 2014 Apr 22;77:323-33. doi: 10.1016/j.ejmech.2014.03.021. Epub 2014 Mar 12.

PMID:
24657569
6.

Synthesis and biological evaluation of 2,4,6-functionalized derivatives of pyrido[2,3-d]pyrimidines as cytotoxic agents and apoptosis inducers.

Sanmartín C, Domínguez MV, Cordeu L, Cubedo E, García-Foncillas J, Font M, Palop JA.

Arch Pharm (Weinheim). 2008 Jan;341(1):28-41.

PMID:
18161903
7.

Synthesis and anticancer activity of some novel fused pyridine ring system.

Elansary AK, Moneer AA, Kadry HH, Gedawy EM.

Arch Pharm Res. 2012 Nov;35(11):1909-17. doi: 10.1007/s12272-012-1107-6. Epub 2012 Dec 4.

PMID:
23212632
8.

Synthesis of novel benzo[4,5]thiazolo[1,2-a]pyrimidine-3-carboxylate derivatives and biological evaluation as potential anticancer agents.

Nagarapu L, Vanaparthi S, Bantu R, Ganesh Kumar C.

Eur J Med Chem. 2013 Nov;69:817-22. doi: 10.1016/j.ejmech.2013.08.024. Epub 2013 Aug 27.

PMID:
24113366
9.

Synthesis and anti-tumor activities of some new pyridines and pyrazolo[1,5-a]pyrimidines.

Ahmed OM, Mohamed MA, Ahmed RR, Ahmed SA.

Eur J Med Chem. 2009 Sep;44(9):3519-23. doi: 10.1016/j.ejmech.2009.03.042. Epub 2009 Apr 8.

PMID:
19398146
10.

Synthesis of pyrrolo[2,3-d]pyrimidine derivatives and their antiproliferative activity against melanoma cell line.

Jung MH, Kim H, Choi WK, El-Gamal MI, Park JH, Yoo KH, Sim TB, Lee SH, Baek D, Hah JM, Cho JH, Oh CH.

Bioorg Med Chem Lett. 2009 Dec 1;19(23):6538-43. doi: 10.1016/j.bmcl.2009.10.051. Epub 2009 Oct 15.

PMID:
19857963
11.

Synthesis and in vitro antiproliferative evaluation of novel N-alkylated 6-isobutyl- and propyl pyrimidine derivatives.

Gazivoda Kraljević T, Ilić N, Stepanić V, Sappe L, Petranović J, Kraljević Pavelić S, Raić-Malić S.

Bioorg Med Chem Lett. 2014 Jul 1;24(13):2913-7. doi: 10.1016/j.bmcl.2014.04.079. Epub 2014 Apr 30.

PMID:
24835982
12.

Novel 6-[(hetero)arylamino]thieno[3,2-b]pyridines: synthesis and antitumoral activities.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, São-José Nascimento M.

Eur J Med Chem. 2010 Dec;45(12):5732-8. doi: 10.1016/j.ejmech.2010.09.030. Epub 2010 Sep 17.

PMID:
20934235
13.

Synthesis and anticancer activity of novel tetralin-6-ylpyridine and tetralin-6-ylpyrimidine derivatives.

Amin KM, El-Zahar MI, Anwar MM, Kamel MM, Mohamed MH.

Acta Pol Pharm. 2009 May-Jun;66(3):279-91.

14.

Synthesis of novel trifluoromethyl substituted furo[2,3-b]pyridine and pyrido[3',2':4,5]furo[3,2-d]pyrimidine derivatives as potential anticancer agents.

Naresh Kumar R, Poornachandra Y, Nagender P, Mallareddy G, Ravi Kumar N, Ranjithreddy P, Ganesh Kumar C, Narsaiah B.

Eur J Med Chem. 2016 Jan 27;108:68-78. doi: 10.1016/j.ejmech.2015.11.007. Epub 2015 Nov 10.

PMID:
26629861
15.

Design, synthesis, and in vitro antiproliferative activity of novel Dasatinib derivatives.

Cai J, Zhang S, Zheng M, Wu X, Chen J, Ji M.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):806-10. doi: 10.1016/j.bmcl.2011.12.070. Epub 2011 Dec 20.

PMID:
22217877
16.

Synthesis of novel thiazolyl-pyrimidines and their anticancer activity in vitro.

Shi HB, Li HB, Lu KQ, Zhu XR, Hu WX, Pei W.

Arch Pharm (Weinheim). 2011 Oct;344(10):675-83. doi: 10.1002/ardp.201000238. Epub 2011 Aug 29.

PMID:
21984017
17.

Synthesis and anticancer activity evaluation of a series of [1,2,4]triazolo[1,5-a]pyridinylpyridines in vitro and in vivo.

Wang XM, Xu J, Li YP, Li H, Jiang CS, Yang GD, Lu SM, Zhang SQ.

Eur J Med Chem. 2013 Sep;67:243-51. doi: 10.1016/j.ejmech.2013.06.052. Epub 2013 Jul 4.

PMID:
23871904
19.

New annelated thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines, with potent anticancer activity, designed through VLAK protocol.

Lauria A, Abbate I, Patella C, Martorana A, Dattolo G, Almerico AM.

Eur J Med Chem. 2013 Apr;62:416-24. doi: 10.1016/j.ejmech.2013.01.019. Epub 2013 Jan 23.

PMID:
23395722
20.

An unexpected Dimroth rearrangement leading to annelated thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with potent antitumor activity.

Lauria A, Patella C, Abbate I, Martorana A, Almerico AM.

Eur J Med Chem. 2013 Jul;65:381-8. doi: 10.1016/j.ejmech.2013.05.012. Epub 2013 May 20.

PMID:
23747807

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