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Items: 1 to 20 of 329

1.

Conservation and variability in the structure and function of the Cas5d endoribonuclease in the CRISPR-mediated microbial immune system.

Koo Y, Ka D, Kim EJ, Suh N, Bae E.

J Mol Biol. 2013 Oct 23;425(20):3799-810. doi: 10.1016/j.jmb.2013.02.032. Epub 2013 Mar 7.

PMID:
23500492
2.

Cutting it close: CRISPR-associated endoribonuclease structure and function.

Hochstrasser ML, Doudna JA.

Trends Biochem Sci. 2015 Jan;40(1):58-66. doi: 10.1016/j.tibs.2014.10.007. Epub 2014 Nov 18. Review.

PMID:
25468820
3.

Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3.

Gong B, Shin M, Sun J, Jung CH, Bolt EL, van der Oost J, Kim JS.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16359-64. doi: 10.1073/pnas.1410806111. Epub 2014 Nov 3.

4.

Cas5d protein processes pre-crRNA and assembles into a cascade-like interference complex in subtype I-C/Dvulg CRISPR-Cas system.

Nam KH, Haitjema C, Liu X, Ding F, Wang H, DeLisa MP, Ke A.

Structure. 2012 Sep 5;20(9):1574-84. doi: 10.1016/j.str.2012.06.016. Epub 2012 Jul 26.

5.

The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.

Fonfara I, Richter H, Bratovič M, Le Rhun A, Charpentier E.

Nature. 2016 Apr 28;532(7600):517-21. doi: 10.1038/nature17945. Epub 2016 Apr 20.

PMID:
27096362
6.

Crystal structure of the Cmr2-Cmr3 subcomplex in the CRISPR-Cas RNA silencing effector complex.

Osawa T, Inanaga H, Numata T.

J Mol Biol. 2013 Oct 23;425(20):3811-23. doi: 10.1016/j.jmb.2013.03.042. Epub 2013 Apr 10.

PMID:
23583914
7.

Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleases.

Garside EL, Schellenberg MJ, Gesner EM, Bonanno JB, Sauder JM, Burley SK, Almo SC, Mehta G, MacMillan AM.

RNA. 2012 Nov;18(11):2020-8. doi: 10.1261/rna.033100.112. Epub 2012 Sep 24.

8.

crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus.

Karvelis T, Gasiunas G, Miksys A, Barrangou R, Horvath P, Siksnys V.

RNA Biol. 2013 May;10(5):841-51. doi: 10.4161/rna.24203. Epub 2013 Mar 27.

9.

Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family.

Hrle A, Maier LK, Sharma K, Ebert J, Basquin C, Urlaub H, Marchfelder A, Conti E.

RNA Biol. 2014;11(8):1072-82. doi: 10.4161/rna.29893.

10.

The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems.

Chylinski K, Le Rhun A, Charpentier E.

RNA Biol. 2013 May;10(5):726-37. doi: 10.4161/rna.24321. Epub 2013 Apr 5.

11.

Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity.

Charpentier E, Richter H, van der Oost J, White MF.

FEMS Microbiol Rev. 2015 May;39(3):428-41. doi: 10.1093/femsre/fuv023. Epub 2015 May 19. Review.

PMID:
25994611
12.

Programmable RNA shredding by the type III-A CRISPR-Cas system of Streptococcus thermophilus.

Tamulaitis G, Kazlauskiene M, Manakova E, Venclovas Č, Nwokeoji AO, Dickman MJ, Horvath P, Siksnys V.

Mol Cell. 2014 Nov 20;56(4):506-17. doi: 10.1016/j.molcel.2014.09.027. Epub 2014 Nov 6.

13.

Crystal structure of the CRISPR-Cas RNA silencing Cmr complex bound to a target analog.

Osawa T, Inanaga H, Sato C, Numata T.

Mol Cell. 2015 May 7;58(3):418-30. doi: 10.1016/j.molcel.2015.03.018. Epub 2015 Apr 23.

14.

Crystal structure of the Csm3-Csm4 subcomplex in the type III-A CRISPR-Cas interference complex.

Numata T, Inanaga H, Sato C, Osawa T.

J Mol Biol. 2015 Jan 30;427(2):259-73. doi: 10.1016/j.jmb.2014.09.029. Epub 2014 Oct 30.

PMID:
25451598
15.

Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6.

Niewoehner O, Jinek M.

RNA. 2016 Mar;22(3):318-29. doi: 10.1261/rna.054098.115. Epub 2016 Jan 13.

16.

Essential requirements for the detection and degradation of invaders by the Haloferax volcanii CRISPR/Cas system I-B.

Maier LK, Lange SJ, Stoll B, Haas KA, Fischer S, Fischer E, Duchardt-Ferner E, Wöhnert J, Backofen R, Marchfelder A.

RNA Biol. 2013 May;10(5):865-74. doi: 10.4161/rna.24282. Epub 2013 Apr 17.

17.

Molecular dynamic simulations of protein/RNA complexes: CRISPR/Csy4 endoribonuclease.

Estarellas C, Otyepka M, Koča J, Banáš P, Krepl M, Šponer J.

Biochim Biophys Acta. 2015 May;1850(5):1072-90. doi: 10.1016/j.bbagen.2014.10.021. Epub 2014 Oct 24.

PMID:
25450173
18.

Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.

Niewoehner O, Jinek M, Doudna JA.

Nucleic Acids Res. 2014 Jan;42(2):1341-53. doi: 10.1093/nar/gkt922. Epub 2013 Oct 22.

19.

Active site plasticity enables metal-dependent tuning of Cas5d nuclease activity in CRISPR-Cas type I-C system.

Punetha A, Sivathanu R, Anand B.

Nucleic Acids Res. 2014 Apr;42(6):3846-56. doi: 10.1093/nar/gkt1335. Epub 2013 Dec 25.

20.

[Progress of genome engineering technology via clustered regularly interspaced short palindromic repeats--a review].

Li H, Qiu S, Song H.

Wei Sheng Wu Xue Bao. 2013 Oct 4;53(10):1025-30. Review. Chinese.

PMID:
24409757

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