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Items: 1 to 20 of 146

1.

IL-6 attenuates trimethyltin-induced cognitive dysfunction via activation of JAK2/STAT3, M1 mAChR and ERK signaling network.

Kim BK, Tran HY, Shin EJ, Lee C, Chung YH, Jeong JH, Bach JH, Kim WK, Park DH, Saito K, Nabeshima T, Kim HC.

Cell Signal. 2013 Jun;25(6):1348-60. doi: 10.1016/j.cellsig.2013.02.017.

PMID:
23499905
2.

Inactivation of JAK2/STAT3 signaling axis and downregulation of M1 mAChR cause cognitive impairment in klotho mutant mice, a genetic model of aging.

Park SJ, Shin EJ, Min SS, An J, Li Z, Hee Chung Y, Hoon Jeong J, Bach JH, Nah SY, Kim WK, Jang CG, Kim YS, Nabeshima Y, Nabeshima T, Kim HC.

Neuropsychopharmacology. 2013 Jul;38(8):1426-37. doi: 10.1038/npp.2013.39.

3.

Protective potential of IL-6 against trimethyltin-induced neurotoxicity in vivo.

Tran HY, Shin EJ, Saito K, Nguyen XK, Chung YH, Jeong JH, Bach JH, Park DH, Yamada K, Nabeshima T, Yoneda Y, Kim HC.

Free Radic Biol Med. 2012 Apr 1;52(7):1159-74. doi: 10.1016/j.freeradbiomed.2011.12.008.

PMID:
22245015
4.

Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons.

Chiba T, Yamada M, Sasabe J, Terashita K, Shimoda M, Matsuoka M, Aiso S.

Mol Psychiatry. 2009 Feb;14(2):206-22. doi: 10.1038/mp.2008.105.

PMID:
18813209
5.
6.

IL-6 regulates MMP-10 expression via JAK2/STAT3 signaling pathway in a human lung adenocarcinoma cell line.

Zhang X, Yin P, DI D, Luo G, Zheng L, Wei J, Zhang J, Shi Y, Zhang J, Xu N.

Anticancer Res. 2009 Nov;29(11):4497-501.

7.

Blockade of Janus kinase-2 signaling ameliorates mouse liver damage due to ischemia and reperfusion.

Freitas MC, Uchida Y, Zhao D, Ke B, Busuttil RW, Kupiec-Weglinski JW.

Liver Transpl. 2010 May;16(5):600-10. doi: 10.1002/lt.22036.

8.
9.

Leptin stimulates interleukin-6 production via janus kinase 2/signal transducer and activator of transcription 3 in rheumatoid synovial fibroblasts.

Muraoka S, Kusunoki N, Takahashi H, Tsuchiya K, Kawai S.

Clin Exp Rheumatol. 2013 Jul-Aug;31(4):589-95.

PMID:
23622344
10.
11.

SOCS3 promotes inflammation and apoptosis via inhibiting JAK2/STAT3 signaling pathway in 3T3-L1 adipocyte.

Liu Z, Gan L, Zhou Z, Jin W, Sun C.

Immunobiology. 2015 Aug;220(8):947-53. doi: 10.1016/j.imbio.2015.02.004.

PMID:
25720636
12.

Anti-inflammation of spirocyclopiperazinium salt compound LXM-10 targeting α7 nAChR and M4 mAChR and inhibiting JAK2/STAT3 pathway in rats.

Zhang W, Sun Q, Gao X, Jiang Y, Li R, Ye J.

PLoS One. 2013 Jun 28;8(6):e66895. doi: 10.1371/journal.pone.0066895.

13.

Voluntary exercise protects hippocampal neurons from trimethyltin injury: possible role of interleukin-6 to modulate tumor necrosis factor receptor-mediated neurotoxicity.

Funk JA, Gohlke J, Kraft AD, McPherson CA, Collins JB, Jean Harry G.

Brain Behav Immun. 2011 Aug;25(6):1063-77. doi: 10.1016/j.bbi.2011.03.012.

14.

Inhibition of Jak2 phosphorylation attenuates pressure overload cardiac hypertrophy.

Beckles DL, Mascareno E, Siddiqui MA.

Vascul Pharmacol. 2006 Dec;45(6):350-7.

PMID:
16822720
15.
16.

Diminished antigen-specific IgG1 and interleukin-6 production and acetylcholinesterase expression in combined M1 and M5 muscarinic acetylcholine receptor knockout mice.

Fujii YX, Tashiro A, Arimoto K, Fujigaya H, Moriwaki Y, Misawa H, Fujii T, Matsui M, Kasahara T, Kawashima K.

J Neuroimmunol. 2007 Aug;188(1-2):80-5.

PMID:
17586055
17.

Angiotensin II activates JAK2/STAT3 pathway and induces interleukin-6 production in cultured rat brainstem astrocytes.

Kandalam U, Clark MA.

Regul Pept. 2010 Jan 8;159(1-3):110-6. doi: 10.1016/j.regpep.2009.09.001.

PMID:
19748527
18.

Flavonoids, a prenatal prophylaxis via targeting JAK2/STAT3 signaling to oppose IL-6/MIA associated autism.

Parker-Athill E, Luo D, Bailey A, Giunta B, Tian J, Shytle RD, Murphy T, Legradi G, Tan J.

J Neuroimmunol. 2009 Dec 10;217(1-2):20-7. doi: 10.1016/j.jneuroim.2009.08.012.

PMID:
19766327
19.

Interleukin-6 inhibition of peroxisome proliferator-activated receptor alpha expression is mediated by JAK2- and PI3K-induced STAT1/3 in HepG2 hepatocyte cells.

Chew GS, Myers S, Shu-Chien AC, Muhammad TS.

Mol Cell Biochem. 2014 Mar;388(1-2):25-37. doi: 10.1007/s11010-013-1896-z.

PMID:
24242046
20.

The absence of interleukin-6 enhanced arsenite-induced renal injury by promoting autophagy of tubular epithelial cells with aberrant extracellular signal-regulated kinase activation.

Kimura A, Ishida Y, Wada T, Hisaoka T, Morikawa Y, Sugaya T, Mukaida N, Kondo T.

Am J Pathol. 2010 Jan;176(1):40-50. doi: 10.2353/ajpath.2010.090146.

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