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Items: 1 to 20 of 74

1.

Knockout of Ste20-like proline/alanine-rich kinase (SPAK) attenuates intestinal inflammation in mice.

Zhang Y, Viennois E, Xiao B, Baker MT, Yang S, Okoro I, Yan Y.

Am J Pathol. 2013 May;182(5):1617-28. doi: 10.1016/j.ajpath.2013.01.028. Epub 2013 Mar 13.

PMID:
23499375
2.

Overexpression of Ste20-related proline/alanine-rich kinase exacerbates experimental colitis in mice.

Yan Y, Laroui H, Ingersoll SA, Ayyadurai S, Charania M, Yang S, Dalmasso G, Obertone TS, Nguyen H, Sitaraman SV, Merlin D.

J Immunol. 2011 Aug 1;187(3):1496-505. doi: 10.4049/jimmunol.1002910. Epub 2011 Jun 24.

3.

Nuclear factor-kappaB is a critical mediator of Ste20-like proline-/alanine-rich kinase regulation in intestinal inflammation.

Yan Y, Dalmasso G, Nguyen HT, Obertone TS, Charrier-Hisamuddin L, Sitaraman SV, Merlin D.

Am J Pathol. 2008 Oct;173(4):1013-28. doi: 10.2353/ajpath.2008.080339. Epub 2008 Sep 11.

4.

MicroRNA-21 knockout improve the survival rate in DSS induced fatal colitis through protecting against inflammation and tissue injury.

Shi C, Liang Y, Yang J, Xia Y, Chen H, Han H, Yang Y, Wu W, Gao R, Qin H.

PLoS One. 2013 Jun 24;8(6):e66814. doi: 10.1371/journal.pone.0066814. Print 2013.

5.

PepT1 expressed in immune cells has an important role in promoting the immune response during experimentally induced colitis.

Ayyadurai S, Charania MA, Xiao B, Viennois E, Merlin D.

Lab Invest. 2013 Aug;93(8):888-99. doi: 10.1038/labinvest.2013.77. Epub 2013 Jun 24.

6.

Early weaning increases intestinal permeability, alters expression of cytokine and tight junction proteins, and activates mitogen-activated protein kinases in pigs.

Hu CH, Xiao K, Luan ZS, Song J.

J Anim Sci. 2013 Mar;91(3):1094-101. doi: 10.2527/jas.2012-5796. Epub 2012 Dec 10.

7.

Lipid rafts are disrupted in mildly inflamed intestinal microenvironments without overt disruption of the epithelial barrier.

Bowie RV, Donatello S, Lyes C, Owens MB, Babina IS, Hudson L, Walsh SV, O'Donoghue DP, Amu S, Barry SP, Fallon PG, Hopkins AM.

Am J Physiol Gastrointest Liver Physiol. 2012 Apr 15;302(8):G781-93. doi: 10.1152/ajpgi.00002.2011. Epub 2012 Jan 12.

8.

Exacerbation of DSS-induced colitis in mice lacking kinin B(1) receptors through compensatory up-regulation of kinin B(2) receptors: the role of tight junctions and intestinal homeostasis.

Marcon R, Claudino RF, Dutra RC, Bento AF, Schmidt EC, Bouzon ZL, Sordi R, Morais RL, Pesquero JB, Calixto JB.

Br J Pharmacol. 2013 Jan;168(2):389-402. doi: 10.1111/j.1476-5381.2012.02136.x.

9.

Probiotic mixture VSL#3 protects the epithelial barrier by maintaining tight junction protein expression and preventing apoptosis in a murine model of colitis.

Mennigen R, Nolte K, Rijcken E, Utech M, Loeffler B, Senninger N, Bruewer M.

Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1140-9. doi: 10.1152/ajpgi.90534.2008. Epub 2009 Feb 12.

10.

[Changes in tight junction protein expression and permeability of colon mucosa in rats with dextran sulfate sodium-induced inflammatory bowel disease].

Rao YX, Chen J, Chen LL, Gu WZ, Shu XL.

Zhongguo Dang Dai Er Ke Za Zhi. 2012 Dec;14(12):976-81. Chinese.

11.

Supplemental naringenin prevents intestinal barrier defects and inflammation in colitic mice.

Azuma T, Shigeshiro M, Kodama M, Tanabe S, Suzuki T.

J Nutr. 2013 Jun;143(6):827-34. doi: 10.3945/jn.113.174508. Epub 2013 Apr 17.

12.
13.

Vasoactive intestinal peptide ameliorates intestinal barrier disruption associated with Citrobacter rodentium-induced colitis.

Conlin VS, Wu X, Nguyen C, Dai C, Vallance BA, Buchan AM, Boyer L, Jacobson K.

Am J Physiol Gastrointest Liver Physiol. 2009 Oct;297(4):G735-50. doi: 10.1152/ajpgi.90551.2008. Epub 2009 Aug 6.

14.

Claudin-2 regulates colorectal inflammation via myosin light chain kinase-dependent signaling.

Nishida M, Yoshida M, Nishiumi S, Furuse M, Azuma T.

Dig Dis Sci. 2013 Jun;58(6):1546-59. doi: 10.1007/s10620-012-2535-3. Epub 2013 Jan 11.

PMID:
23306855
15.

Cingulin is dispensable for epithelial barrier function and tight junction structure, and plays a role in the control of claudin-2 expression and response to duodenal mucosa injury.

Guillemot L, Schneider Y, Brun P, Castagliuolo I, Pizzuti D, Martines D, Jond L, Bongiovanni M, Citi S.

J Cell Sci. 2012 Nov 1;125(Pt 21):5005-14. doi: 10.1242/jcs.101261. Epub 2012 Sep 3.

16.

Unexpected role of anticoagulant protein C in controlling epithelial barrier integrity and intestinal inflammation.

Vetrano S, Ploplis VA, Sala E, Sandoval-Cooper M, Donahue DL, Correale C, Arena V, Spinelli A, Repici A, Malesci A, Castellino FJ, Danese S.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19830-5. doi: 10.1073/pnas.1107140108. Epub 2011 Nov 22.

17.

Resistin-like molecule α promotes pathogenic Th17 cell responses and bacterial-induced intestinal inflammation.

Osborne LC, Joyce KL, Alenghat T, Sonnenberg GF, Giacomin PR, Du Y, Bergstrom KS, Vallance BA, Nair MG.

J Immunol. 2013 Mar 1;190(5):2292-300. doi: 10.4049/jimmunol.1200706. Epub 2013 Jan 25.

18.

A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis.

Ungaro R, Fukata M, Hsu D, Hernandez Y, Breglio K, Chen A, Xu R, Sotolongo J, Espana C, Zaias J, Elson G, Mayer L, Kosco-Vilbois M, Abreu MT.

Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1167-79. doi: 10.1152/ajpgi.90496.2008. Epub 2009 Apr 9.

19.

Lactobacillus plantarum ameliorates colonic epithelial barrier dysfunction by modulating the apical junctional complex and PepT1 in IL-10 knockout mice.

Chen HQ, Yang J, Zhang M, Zhou YK, Shen TY, Chu ZX, Zhang M, Hang XM, Jiang YQ, Qin HL.

Am J Physiol Gastrointest Liver Physiol. 2010 Dec;299(6):G1287-97. doi: 10.1152/ajpgi.00196.2010. Epub 2010 Sep 30.

20.

Cloning and characterization of a new intestinal inflammation-associated colonic epithelial Ste20-related protein kinase isoform.

Yan Y, Nguyen H, Dalmasso G, Sitaraman SV, Merlin D.

Biochim Biophys Acta. 2007 Feb;1769(2):106-16. Epub 2007 Jan 23.

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