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Items: 1 to 20 of 159

1.

DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes.

Aran D, Sabato S, Hellman A.

Genome Biol. 2013 Mar 12;14(3):R21. doi: 10.1186/gb-2013-14-3-r21.

2.

Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity.

Schmidl C, Klug M, Boeld TJ, Andreesen R, Hoffmann P, Edinger M, Rehli M.

Genome Res. 2009 Jul;19(7):1165-74. doi: 10.1101/gr.091470.109.

4.

Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer.

Heyn H, Vidal E, Ferreira HJ, Vizoso M, Sayols S, Gomez A, Moran S, Boque-Sastre R, Guil S, Martinez-Cardus A, Lin CY, Royo R, Sanchez-Mut JV, Martinez R, Gut M, Torrents D, Orozco M, Gut I, Young RA, Esteller M.

Genome Biol. 2016 Jan 26;17:11. doi: 10.1186/s13059-016-0879-2.

5.

Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters.

Shen L, Kondo Y, Guo Y, Zhang J, Zhang L, Ahmed S, Shu J, Chen X, Waterland RA, Issa JP.

PLoS Genet. 2007 Oct;3(10):2023-36.

6.

Tissue-specific effects of genetic and epigenetic variation on gene regulation and splicing.

Gutierrez-Arcelus M, Ongen H, Lappalainen T, Montgomery SB, Buil A, Yurovsky A, Bryois J, Padioleau I, Romano L, Planchon A, Falconnet E, Bielser D, Gagnebin M, Giger T, Borel C, Letourneau A, Makrythanasis P, Guipponi M, Gehrig C, Antonarakis SE, Dermitzakis ET.

PLoS Genet. 2015 Jan 29;11(1):e1004958. doi: 10.1371/journal.pgen.1004958.

7.

Chromosomal losses are associated with hypomethylation of the gene-control regions in the stomach with a low number of active genes.

Jung YC, Hong SJ, Kim YH, Kim SJ, Kang SJ, Choi SW, Rhyu MG.

J Korean Med Sci. 2008 Dec;23(6):1068-89. doi: 10.3346/jkms.2008.23.6.1068.

8.

Identification of cis regulatory features in the embryonic zebrafish genome through large-scale profiling of H3K4me1 and H3K4me3 binding sites.

Aday AW, Zhu LJ, Lakshmanan A, Wang J, Lawson ND.

Dev Biol. 2011 Sep 15;357(2):450-62. doi: 10.1016/j.ydbio.2011.03.007.

9.

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.

Agirre X, Castellano G, Pascual M, Heath S, Kulis M, Segura V, Bergmann A, Esteve A, Merkel A, Raineri E, Agueda L, Blanc J, Richardson D, Clarke L, Datta A, Russiñol N, Queirós AC, Beekman R, Rodríguez-Madoz JR, San José-Enériz E, Fang F, Gutiérrez NC, García-Verdugo JM, Robson MI, Schirmer EC, Guruceaga E, Martens JH, Gut M, Calasanz MJ, Flicek P, Siebert R, Campo E, Miguel JF, Melnick A, Stunnenberg HG, Gut IG, Prosper F, Martín-Subero JI.

Genome Res. 2015 Apr;25(4):478-87. doi: 10.1101/gr.180240.114.

10.
11.

Exploring breast carcinogenesis through integrative genomics and epigenomics analyses.

Minning C, Mokhtar NM, Abdullah N, Muhammad R, Emran NA, Ali SA, Harun R, Jamal R.

Int J Oncol. 2014 Nov;45(5):1959-68. doi: 10.3892/ijo.2014.2625.

PMID:
25175708
12.

Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions.

Feldmann A, Ivanek R, Murr R, Gaidatzis D, Burger L, Schübeler D.

PLoS Genet. 2013;9(12):e1003994. doi: 10.1371/journal.pgen.1003994.

13.

Embryonic Stem Cell (ES)-Specific Enhancers Specify the Expression Potential of ES Genes in Cancer.

Aran D, Abu-Remaileh M, Levy R, Meron N, Toperoff G, Edrei Y, Bergman Y, Hellman A.

PLoS Genet. 2016 Feb 17;12(2):e1005840. doi: 10.1371/journal.pgen.1005840.

14.

Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements.

Zhang W, Spector TD, Deloukas P, Bell JT, Engelhardt BE.

Genome Biol. 2015 Jan 24;16:14. doi: 10.1186/s13059-015-0581-9.

15.

TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.

Yamazaki J, Jelinek J, Lu Y, Cesaroni M, Madzo J, Neumann F, He R, Taby R, Vasanthakumar A, Macrae T, Ostler KR, Kantarjian HM, Liang S, Estecio MR, Godley LA, Issa JP.

Cancer Res. 2015 Jul 15;75(14):2833-43. doi: 10.1158/0008-5472.CAN-14-0739.

16.

DNA methylation in glioblastoma: impact on gene expression and clinical outcome.

Etcheverry A, Aubry M, de Tayrac M, Vauleon E, Boniface R, Guenot F, Saikali S, Hamlat A, Riffaud L, Menei P, Quillien V, Mosser J.

BMC Genomics. 2010 Dec 14;11:701. doi: 10.1186/1471-2164-11-701.

18.

Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer.

Wee EJ, Peters K, Nair SS, Hulf T, Stein S, Wagner S, Bailey P, Lee SY, Qu WJ, Brewster B, French JD, Dobrovic A, Francis GD, Clark SJ, Brown MA.

Oncogene. 2012 Sep 20;31(38):4182-95. doi: 10.1038/onc.2011.584.

19.

Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer.

Taberlay PC, Statham AL, Kelly TK, Clark SJ, Jones PA.

Genome Res. 2014 Sep;24(9):1421-32. doi: 10.1101/gr.163485.113.

20.

Hypermethylation of a New Distal Sodium/Iodide Symporter (NIS) enhancer (NDE) is associated with reduced NIS expression in thyroid tumors.

Galrão AL, Camargo RY, Friguglietti CU, Moraes L, Cerutti JM, Serrano-Nascimento C, Suzuki MF, Medeiros-Neto G, Rubio IG.

J Clin Endocrinol Metab. 2014 Jun;99(6):E944-52. doi: 10.1210/jc.2013-1450.

PMID:
24432988
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