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Annexin A5-functionalized nanoparticle for multimodal imaging of cell death.

Zhang R, Huang M, Zhou M, Wen X, Huang Q, Li C.

Mol Imaging. 2013 May;12(3):182-90.


Annexin A5-conjugated polymeric micelles for dual SPECT and optical detection of apoptosis.

Zhang R, Lu W, Wen X, Huang M, Zhou M, Liang D, Li C.

J Nucl Med. 2011 Jun;52(6):958-64. doi: 10.2967/jnumed.110.083220. Epub 2011 May 13.


111In-Labeled annexin A5-polyethylene glycol–coated core-cross-linked polymeric micelle-Cy7.

Leung K.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2011 Nov 30 [updated 2012 Jan 19].


Annexin A5-conjugated quantum dots with a paramagnetic lipidic coating for the multimodal detection of apoptotic cells.

van Tilborg GA, Mulder WJ, Chin PT, Storm G, Reutelingsperger CP, Nicolay K, Strijkers GJ.

Bioconjug Chem. 2006 Jul-Aug;17(4):865-8.


Preliminary in vivo evaluation of a novel 99mTc-labeled HYNIC-cys-annexin A5 as an apoptosis imaging agent.

Fonge H, de Saint Hubert M, Vunckx K, Rattat D, Nuyts J, Bormans G, Ni Y, Reutelingsperger C, Verbruggen A.

Bioorg Med Chem Lett. 2008 Jul 1;18(13):3794-8. doi: 10.1016/j.bmcl.2008.05.044. Epub 2008 May 16.


Annexin A5-functionalized bimodal nanoparticles for MRI and fluorescence imaging of atherosclerotic plaques.

van Tilborg GA, Vucic E, Strijkers GJ, Cormode DP, Mani V, Skajaa T, Reutelingsperger CP, Fayad ZA, Mulder WJ, Nicolay K.

Bioconjug Chem. 2010 Oct 20;21(10):1794-803. doi: 10.1021/bc100091q.


Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts.

Zhang R, Xiong C, Huang M, Zhou M, Huang Q, Wen X, Liang D, Li C.

Biomaterials. 2011 Sep;32(25):5872-9. doi: 10.1016/j.biomaterials.2011.04.070. Epub 2011 May 25.


Past, present, and future of annexin A5: from protein discovery to clinical applications.

Boersma HH, Kietselaer BL, Stolk LM, Bennaghmouch A, Hofstra L, Narula J, Heidendal GA, Reutelingsperger CP.

J Nucl Med. 2005 Dec;46(12):2035-50. Review.


A dual-labeled Annexin A5 is not suited for SPECT imaging of brain cell death in experimental murine stroke.

Zille M, Harhausen D, De Saint-Hubert M, Michel R, Reutelingsperger CP, Dirnagl U, Wunder A.

J Cereb Blood Flow Metab. 2014 Sep;34(9). doi: 10.1038/jcbfm.2014.115. Epub 2014 Jul 2.


Annexin A5: an imaging biomarker of cardiovascular risk.

Laufer EM, Reutelingsperger CP, Narula J, Hofstra L.

Basic Res Cardiol. 2008 Mar;103(2):95-104. doi: 10.1007/s00395-008-0701-8. Review.


Preliminary biological evaluation of novel (99m)Tc-Cys-annexin A5 as a apoptosis imaging agent.

Lu C, Jiang Q, Hu M, Tan C, Ji Y, Yu H, Hua Z.

Molecules. 2013 Jun 10;18(6):6908-18. doi: 10.3390/molecules18066908.


Molecular imaging of apoptosis with radio-labeled Annexin A5 focused on the evaluation of tumor response to chemotherapy.

Kuge Y, Zhao S, Takei T, Tamaki N.

Anticancer Agents Med Chem. 2009 Nov;9(9):1003-11. Review.


Noninvasive detection of programmed cell loss with 99mTc-labeled annexin A5 in heart failure.

Kietselaer BL, Reutelingsperger CP, Boersma HH, Heidendal GA, Liem IH, Crijns HJ, Narula J, Hofstra L.

J Nucl Med. 2007 Apr;48(4):562-7.


XTEN-annexin A5: XTEN allows complete expression of long-circulating protein-based imaging probes as recombinant alternative to PEGylation.

Haeckel A, Appler F, Figge L, Kratz H, Lukas M, Michel R, Schnorr J, Zille M, Hamm B, Schellenberger E.

J Nucl Med. 2014 Mar;55(3):508-14. doi: 10.2967/jnumed.113.128108. Epub 2014 Feb 18.


Near-infrared fluorescent imaging of tumor apoptosis.

Petrovsky A, Schellenberger E, Josephson L, Weissleder R, Bogdanov A Jr.

Cancer Res. 2003 Apr 15;63(8):1936-42.


Optical and magnetic resonance imaging of cell death and platelet activation using annexin a5-functionalized quantum dots.

Prinzen L, Miserus RJ, Dirksen A, Hackeng TM, Deckers N, Bitsch NJ, Megens RT, Douma K, Heemskerk JW, Kooi ME, Frederik PM, Slaaf DW, van Zandvoort MA, Reutelingsperger CP.

Nano Lett. 2007 Jan;7(1):93-100.


Synthesis and radiolabeling of (111)In-core-cross linked polymeric micelle-octreotide for near-infrared fluoroscopy and single photon emission computed tomography imaging.

Hong Y, Zhu H, Hu J, Lin X, Wang F, Li C, Yang Z.

Bioorg Med Chem Lett. 2014 Jun 15;24(12):2781-5. doi: 10.1016/j.bmcl.2014.03.050. Epub 2014 Mar 25.


Investigation of a potential scintigraphic tracer for imaging apoptosis: radioiodinated annexin V-Kunitz protease inhibitor fusion protein.

Liao MH, Jan TR, Chiang CC, Yen KC, Liao TZ, Chen MW, Chi CW, Wun TC, Yen TC, Wey SP.

J Biomed Biotechnol. 2011;2011:675701. doi: 10.1155/2011/675701. Epub 2011 Apr 27.


99mTc-Annexin A5 uptake and imaging to monitor chemosensitivity.

Belhocine TZ, Blankenberg FG.

Methods Mol Med. 2005;111:363-80.


In vitro measurement of cell death with the annexin A5 affinity assay.

van Genderen H, Kenis H, Lux P, Ungeth L, Maassen C, Deckers N, Narula J, Hofstra L, Reutelingsperger C.

Nat Protoc. 2006;1(1):363-7.


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