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Items: 1 to 20 of 105

1.

The impact of microcarrier culture optimization on the glycosylation profile of a monoclonal antibody.

Costa AR, Withers J, Rodrigues ME, McLoughlin N, Henriques M, Oliveira R, Rudd PM, Azeredo J.

Springerplus. 2013 Dec;2(1):25. doi: 10.1186/2193-1801-2-25. Epub 2013 Jan 28.

2.

Evaluation of macroporous and microporous carriers for CHO-K1 cell growth and monoclonal antibody production.

Rodrigues ME, Costa AR, Fernandes P, Henriques M, Cunnah P, Melton DW, Azeredo J, Oliveira R.

J Microbiol Biotechnol. 2013 Sep 28;23(9):1308-21.

3.

The impact of cell adaptation to serum-free conditions on the glycosylation profile of a monoclonal antibody produced by Chinese hamster ovary cells.

Costa AR, Withers J, Rodrigues ME, McLoughlin N, Henriques M, Oliveira R, Rudd PM, Azeredo J.

N Biotechnol. 2013 Jun 25;30(5):563-72. doi: 10.1016/j.nbt.2012.12.002. Epub 2012 Dec 13.

PMID:
23247406
4.

The effects of culture conditions on the glycosylation of secreted human placental alkaline phosphatase produced in Chinese hamster ovary cells.

Nam JH, Zhang F, Ermonval M, Linhardt RJ, Sharfstein ST.

Biotechnol Bioeng. 2008 Aug 15;100(6):1178-92. doi: 10.1002/bit.21853.

5.

Cell attachment to microcarriers affects growth, metabolic activity, and culture productivity in bioreactor culture.

Nam JH, Ermonval M, Sharfstein ST.

Biotechnol Prog. 2007 May-Jun;23(3):652-60. Epub 2007 May 15.

PMID:
17500530
6.

Effects of nutrient levels and average culture pH on the glycosylation pattern of camelid-humanized monoclonal antibody.

Aghamohseni H, Ohadi K, Spearman M, Krahn N, Moo-Young M, Scharer JM, Butler M, Budman HM.

J Biotechnol. 2014 Sep 30;186:98-109. doi: 10.1016/j.jbiotec.2014.05.024. Epub 2014 Jul 8.

PMID:
25014402
7.

Evaluating the impact of cell culture process parameters on monoclonal antibody N-glycosylation.

Ivarsson M, Villiger TK, Morbidelli M, Soos M.

J Biotechnol. 2014 Oct 20;188:88-96. doi: 10.1016/j.jbiotec.2014.08.026. Epub 2014 Aug 28.

PMID:
25173615
8.

Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation.

Fan Y, Jimenez Del Val I, Müller C, Wagtberg Sen J, Rasmussen SK, Kontoravdi C, Weilguny D, Andersen MR.

Biotechnol Bioeng. 2015 Mar;112(3):521-35. doi: 10.1002/bit.25450. Epub 2014 Oct 10.

PMID:
25220616
9.

CHO cell line specific prediction and control of recombinant monoclonal antibody N-glycosylation.

Grainger RK, James DC.

Biotechnol Bioeng. 2013 Nov;110(11):2970-83. doi: 10.1002/bit.24959. Epub 2013 Jun 6.

PMID:
23737295
10.

Model-based investigation of intracellular processes determining antibody Fc-glycosylation under mild hypothermia.

Sou SN, Jedrzejewski PM, Lee K, Sellick C, Polizzi KM, Kontoravdi C.

Biotechnol Bioeng. 2017 Jul;114(7):1570-1582. doi: 10.1002/bit.26225. Epub 2017 Mar 10.

11.

[Optimization of attachment conditions for rabbit mesenchymal stem cells in cytodex 3 microcarrier culture systems].

Jiang D, Hu J, Zhou Y, Tan W.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2007 Aug;24(4):884-8. Chinese.

PMID:
17899766
12.

The effects of microcarrier culture on recombinant CHO cells under biphasic hypothermic culture conditions.

Nam JH, Ermonval M, Sharfstein ST.

Cytotechnology. 2009 Mar;59(2):81-91. doi: 10.1007/s10616-009-9196-x. Epub 2009 May 2.

13.

Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.

Hills AE, Patel A, Boyd P, James DC.

Biotechnol Bioeng. 2001 Oct 20;75(2):239-51.

PMID:
11536148
14.

Production and glycosylation of recombinant beta-interferon in suspension and cytopore microcarrier cultures of CHO cells.

Spearman M, Rodriguez J, Huzel N, Butler M.

Biotechnol Prog. 2005 Jan-Feb;21(1):31-9.

PMID:
15903238
15.

Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells.

Hong JK, Lee SM, Kim KY, Lee GM.

Appl Microbiol Biotechnol. 2014 Jun;98(12):5417-25. doi: 10.1007/s00253-014-5596-8. Epub 2014 Feb 21.

PMID:
24557571
16.

Monitoring recombinant human interferon-gamma N-glycosylation during perfused fluidized-bed and stirred-tank batch culture of CHO cells.

Goldman MH, James DC, Rendall M, Ison AP, Hoare M, Bull AT.

Biotechnol Bioeng. 1998 Dec 5;60(5):596-607.

PMID:
10099468
17.

The availability of glucose to CHO cells affects the intracellular lipid-linked oligosaccharide distribution, site occupancy and the N-glycosylation profile of a monoclonal antibody.

Liu B, Spearman M, Doering J, Lattová E, Perreault H, Butler M.

J Biotechnol. 2014 Jan 20;170:17-27. doi: 10.1016/j.jbiotec.2013.11.007. Epub 2013 Nov 25.

PMID:
24286971
18.

How does mild hypothermia affect monoclonal antibody glycosylation?

Sou SN, Sellick C, Lee K, Mason A, Kyriakopoulos S, Polizzi KM, Kontoravdi C.

Biotechnol Bioeng. 2015 Jun;112(6):1165-76. doi: 10.1002/bit.25524. Epub 2015 Apr 17.

PMID:
25545631
19.
20.

Production of reovirus type-1 and type-3 from Vero cells grown on solid and macroporous microcarriers.

Berry JM, Barnabé N, Coombs KM, Butler M.

Biotechnol Bioeng. 1999 Jan 5;62(1):12-9.

PMID:
10099508

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