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Items: 1 to 20 of 136


Quantification of cellular and nuclear uptake rates of polymeric gene delivery nanoparticles and DNA plasmids via flow cytometry.

Bishop CJ, Majewski RL, Guiriba TR, Wilson DR, Bhise NS, Quiñones-Hinojosa A, Green JJ.

Acta Biomater. 2016 Jun;37:120-30. doi: 10.1016/j.actbio.2016.03.036. Epub 2016 Mar 24.


Gene delivery nanoparticles specific for human microvasculature and macrovasculature.

Shmueli RB, Sunshine JC, Xu Z, Duh EJ, Green JJ.

Nanomedicine. 2012 Oct;8(7):1200-7. doi: 10.1016/j.nano.2012.01.006. Epub 2012 Feb 1.


A combinatorial polymer library approach yields insight into nonviral gene delivery.

Green JJ, Langer R, Anderson DG.

Acc Chem Res. 2008 Jun;41(6):749-59. doi: 10.1021/ar7002336.


Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity.

Eltoukhy AA, Siegwart DJ, Alabi CA, Rajan JS, Langer R, Anderson DG.

Biomaterials. 2012 May;33(13):3594-603. doi: 10.1016/j.biomaterials.2012.01.046. Epub 2012 Feb 14.


The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures.

Bhise NS, Gray RS, Sunshine JC, Htet S, Ewald AJ, Green JJ.

Biomaterials. 2010 Nov;31(31):8088-96. doi: 10.1016/j.biomaterials.2010.07.023. Epub 2010 Jul 31.


Evaluating the potential of poly(beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cells.

Bhise NS, Wahlin KJ, Zack DJ, Green JJ.

Int J Nanomedicine. 2013;8:4641-58. doi: 10.2147/IJN.S53830. Epub 2013 Dec 4.


Poly(β-amino ester)-nanoparticle mediated transfection of retinal pigment epithelial cells in vitro and in vivo.

Sunshine JC, Sunshine SB, Bhutto I, Handa JT, Green JJ.

PLoS One. 2012;7(5):e37543. doi: 10.1371/journal.pone.0037543. Epub 2012 May 21.


Bioreducible cationic polymer-based nanoparticles for efficient and environmentally triggered cytoplasmic siRNA delivery to primary human brain cancer cells.

Kozielski KL, Tzeng SY, De Mendoza BA, Green JJ.

ACS Nano. 2014 Apr 22;8(4):3232-41. doi: 10.1021/nn500704t. Epub 2014 Apr 3.


Synthesis and application of poly(ethylene glycol)-co-poly(β-amino ester) copolymers for small cell lung cancer gene therapy.

Kim J, Kang Y, Tzeng SY, Green JJ.

Acta Biomater. 2016 Sep 1;41:293-301. doi: 10.1016/j.actbio.2016.05.040. Epub 2016 Jun 1.


Trigger-responsive, fast-degradable poly(β-amino ester)s for enhanced DNA unpackaging and reduced toxicity.

Deng X, Zheng N, Song Z, Yin L, Cheng J.

Biomaterials. 2014 Jun;35(18):5006-15. doi: 10.1016/j.biomaterials.2014.03.005. Epub 2014 Mar 24.


Preparation, characterization and transfection efficiency of cationic PEGylated PLA nanoparticles as gene delivery systems.

Chen J, Tian B, Yin X, Zhang Y, Hu D, Hu Z, Liu M, Pan Y, Zhao J, Li H, Hou C, Wang J, Zhang Y.

J Biotechnol. 2007 Jun 15;130(2):107-13. Epub 2007 Feb 17.


Subtle changes to polymer structure and degradation mechanism enable highly effective nanoparticles for siRNA and DNA delivery to human brain cancer.

Tzeng SY, Green JJ.

Adv Healthc Mater. 2013 Mar;2(3):468-80. doi: 10.1002/adhm.201200257. Epub 2012 Sep 26.


Continuous microfluidic assembly of biodegradable poly(beta-amino ester)/DNA nanoparticles for enhanced gene delivery.

Wilson DR, Mosenia A, Suprenant MP, Upadhya R, Routkevitch D, Meyer RA, Quinones-Hinojosa A, Green JJ.

J Biomed Mater Res A. 2017 Jun;105(6):1813-1825. doi: 10.1002/jbm.a.36033. Epub 2017 Apr 12.


Poly(beta-amino esters): procedures for synthesis and gene delivery.

Green JJ, Zugates GT, Langer R, Anderson DG.

Methods Mol Biol. 2009;480:53-63. doi: 10.1007/978-1-59745-429-2_4.


Acid-degradable cationic methacrylamide polymerized in the presence of plasmid DNA as tunable non-viral gene carrier.

Ko IK, Ziady A, Lu S, Kwon YJ.

Biomaterials. 2008 Oct;29(28):3872-81. doi: 10.1016/j.biomaterials.2008.06.003. Epub 2008 Jun 27.


Enzymatic PEGylated Poly(lactone-co-β-amino ester) Nanoparticles as Biodegradable, Biocompatible and Stable Vectors for Gene Delivery.

Chen Y, Li Y, Gao J, Cao Z, Jiang Q, Liu J, Jiang Z.

ACS Appl Mater Interfaces. 2016 Jan 13;8(1):490-501. doi: 10.1021/acsami.5b09437. Epub 2015 Dec 30.


Niemann-Pick C1 affects the gene delivery efficacy of degradable polymeric nanoparticles.

Eltoukhy AA, Sahay G, Cunningham JM, Anderson DG.

ACS Nano. 2014 Aug 26;8(8):7905-13. doi: 10.1021/nn501630h. Epub 2014 Jul 16.


Sonic hedgehog intradermal gene therapy using a biodegradable poly(β-amino esters) nanoparticle to enhance wound healing.

Park HJ, Lee J, Kim MJ, Kang TJ, Jeong Y, Um SH, Cho SW.

Biomaterials. 2012 Dec;33(35):9148-56. doi: 10.1016/j.biomaterials.2012.09.005. Epub 2012 Sep 25.


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