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Items: 1 to 20 of 98

1.

Expression of heterologous proteins flanked by NS3-4A cleavage sites within the hepatitis C virus polyprotein.

Horwitz JA, Dorner M, Friling T, Donovan BM, Vogt A, Loureiro J, Oh T, Rice CM, Ploss A.

Virology. 2013 Apr 25;439(1):23-33. doi: 10.1016/j.virol.2013.01.019. Epub 2013 Feb 26.

2.

Polyprotein-Driven Formation of Two Interdependent Sets of Complexes Supporting Hepatitis C Virus Genome Replication.

Gomes RG, Isken O, Tautz N, McLauchlan J, McCormick CJ.

J Virol. 2015 Dec 30;90(6):2868-83. doi: 10.1128/JVI.01931-15.

3.

NS5A Domain 1 and Polyprotein Cleavage Kinetics Are Critical for Induction of Double-Membrane Vesicles Associated with Hepatitis C Virus Replication.

Romero-Brey I, Berger C, Kallis S, Kolovou A, Paul D, Lohmann V, Bartenschlager R.

MBio. 2015 Jul 7;6(4):e00759. doi: 10.1128/mBio.00759-15.

4.

Transient replication of a hepatitis C virus genotype 1b replicon chimera encoding NS5A-5B from genotype 3a.

Kylefjord H, Danielsson A, Sedig S, Belda O, Wiktelius D, Vrang L, Targett-Adams P.

J Virol Methods. 2014 Jan;195:156-63. doi: 10.1016/j.jviromet.2013.09.017. Epub 2013 Oct 10.

PMID:
24120570
5.

Establishment of an indicator cell system for hepatitis C virus.

Tanaka Y, Mori Y, Tani H, Abe T, Moriishi K, Kojima H, Nagano T, Okabe T, Suzuki T, Tatsumi M, Matsuura Y.

Microbiol Immunol. 2010 Apr;54(4):206-20. doi: 10.1111/j.1348-0421.2010.00209.x.

7.

A cell culture adapted HCV JFH1 variant that increases viral titers and permits the production of high titer infectious chimeric reporter viruses.

Liu S, Xiao L, Nelson C, Hagedorn CH.

PLoS One. 2012;7(9):e44965. doi: 10.1371/journal.pone.0044965. Epub 2012 Sep 13. Erratum in: PLoS One. 2013;8(5). doi:10.1371/annotation/2e81c9a3-4700-4869-aee9-f079092c77cd. Hagedorn, Curt [corrected to Hagedorn, Curt H].

8.

Molecular virology of the hepatitis C virus.

De Francesco R.

J Hepatol. 1999;31 Suppl 1:47-53. Review.

PMID:
10622560
9.

Kinetic and structural analyses of hepatitis C virus polyprotein processing.

Bartenschlager R, Ahlborn-Laake L, Mous J, Jacobsen H.

J Virol. 1994 Aug;68(8):5045-55.

10.

Molecular virology of hepatitis C virus: an update with respect to potential antiviral targets.

Blight KJ, Kolykhalov AA, Reed KE, Agapov EV, Rice CM.

Antivir Ther. 1998;3(Suppl 3):71-81. Review.

PMID:
10726057
11.

Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics.

Kaul A, Stauffer S, Berger C, Pertel T, Schmitt J, Kallis S, Zayas M, Lohmann V, Luban J, Bartenschlager R.

PLoS Pathog. 2009 Aug;5(8):e1000546. doi: 10.1371/journal.ppat.1000546. Epub 2009 Aug 14. Erratum in: PLoS Pathog. 2009 Sep;5(9). doi: 10.1371/annotation/29dffb2a-5d37-4196-b166-b0b15bc2f3fd. Lopez, Margarita Zayas [corrected to Zayas, Margarita].

12.

A hepatitis C virus (HCV) NS3/4A protease-dependent strategy for the identification and purification of HCV-infected cells.

Breiman A, Vitour D, Vilasco M, Ottone C, Molina S, Pichard L, Fournier C, Delgrange D, Charneau P, Duverlie G, Wychowski C, Maurel P, Meurs EF.

J Gen Virol. 2006 Dec;87(Pt 12):3587-98.

PMID:
17098974
13.

Chimeric Sindbis viruses dependent on the NS3 protease of hepatitis C virus.

Filocamo G, Pacini L, Migliaccio G.

J Virol. 1997 Feb;71(2):1417-27.

14.

Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice.

Shi N, Hiraga N, Imamura M, Hayes CN, Zhang Y, Kosaka K, Okazaki A, Murakami E, Tsuge M, Abe H, Aikata H, Takahashi S, Ochi H, Tateno-Mukaidani C, Yoshizato K, Matsui H, Kanai A, Inaba T, McPhee F, Gao M, Chayama K.

Gut. 2013 Jul;62(7):1055-61. doi: 10.1136/gutjnl-2012-302600. Epub 2013 Jan 15.

PMID:
23322441
15.

Identification of amino acid variants in the hepatitis C virus non-structural protein 4A.

Bermúdez-Aguirre AD, Padilla-Noriega L, Zenteno E, Reyes-Leyva J.

Tohoku J Exp Med. 2009 Jul;218(3):165-75.

16.

Hepatitis C virus RNA replication depends on specific cis- and trans-acting activities of viral nonstructural proteins.

Kazakov T, Yang F, Ramanathan HN, Kohlway A, Diamond MS, Lindenbach BD.

PLoS Pathog. 2015 Apr 13;11(4):e1004817. doi: 10.1371/journal.ppat.1004817. eCollection 2015 Apr.

17.

Regulation of hepatitis C virus polyprotein processing by signal peptidase involves structural determinants at the p7 sequence junctions.

Carrère-Kremer S, Montpellier C, Lorenzo L, Brulin B, Cocquerel L, Belouzard S, Penin F, Dubuisson J.

J Biol Chem. 2004 Oct 1;279(40):41384-92. Epub 2004 Jul 7.

18.
19.

Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by NS3.

Manabe S, Fuke I, Tanishita O, Kaji C, Gomi Y, Yoshida S, Mori C, Takamizawa A, Yosida I, Okayama H.

Virology. 1994 Feb;198(2):636-44.

PMID:
8291245
20.

Protease Inhibitors Block Multiple Functions of the NS3/4A Protease-Helicase during the Hepatitis C Virus Life Cycle.

McGivern DR, Masaki T, Lovell W, Hamlett C, Saalau-Bethell S, Graham B.

J Virol. 2015 May;89(10):5362-70. doi: 10.1128/JVI.03188-14. Epub 2015 Mar 4.

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