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Metabolic and immunomodulatory effects of n-3 fatty acids are different in mesenteric and epididymal adipose tissue of diet-induced obese mice.

Ludwig T, Worsch S, Heikenwalder M, Daniel H, Hauner H, Bader BL.

Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1140-56. doi: 10.1152/ajpendo.00171.2012. Epub 2013 Mar 12.


Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids.

Todoric J, Löffler M, Huber J, Bilban M, Reimers M, Kadl A, Zeyda M, Waldhäusl W, Stulnig TM.

Diabetologia. 2006 Sep;49(9):2109-19. Epub 2006 Jun 17.


Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids.

Flachs P, Rühl R, Hensler M, Janovska P, Zouhar P, Kus V, Macek Jilkova Z, Papp E, Kuda O, Svobodova M, Rossmeisl M, Tsenov G, Mohamed-Ali V, Kopecky J.

Diabetologia. 2011 Oct;54(10):2626-38. doi: 10.1007/s00125-011-2233-2. Epub 2011 Jul 21.


A high ratio of dietary n-3/n-6 polyunsaturated fatty acids improves obesity-linked inflammation and insulin resistance through suppressing activation of TLR4 in SD rats.

Liu HQ, Qiu Y, Mu Y, Zhang XJ, Liu L, Hou XH, Zhang L, Xu XN, Ji AL, Cao R, Yang RH, Wang F.

Nutr Res. 2013 Oct;33(10):849-58. doi: 10.1016/j.nutres.2013.07.004. Epub 2013 Aug 9.


Prevention of high-fat diet-induced adipose tissue remodeling in obese diabetic mice by n-3 polyunsaturated fatty acids.

Huber J, Löffler M, Bilban M, Reimers M, Kadl A, Todoric J, Zeyda M, Geyeregger R, Schreiner M, Weichhart T, Leitinger N, Waldhäusl W, Stulnig TM.

Int J Obes (Lond). 2007 Jun;31(6):1004-13. Epub 2006 Nov 28.


Eicosapentaenoic acid reduces adipocyte hypertrophy and inflammation in diet-induced obese mice in an adiposity-independent manner.

LeMieux MJ, Kalupahana NS, Scoggin S, Moustaid-Moussa N.

J Nutr. 2015 Mar;145(3):411-7. doi: 10.3945/jn.114.202952. Epub 2014 Dec 31.


Preservation of metabolic flexibility in skeletal muscle by a combined use of n-3 PUFA and rosiglitazone in dietary obese mice.

Horakova O, Medrikova D, van Schothorst EM, Bunschoten A, Flachs P, Kus V, Kuda O, Bardova K, Janovska P, Hensler M, Rossmeisl M, Wang-Sattler R, Prehn C, Adamski J, Illig T, Keijer J, Kopecky J.

PLoS One. 2012;7(8):e43764. doi: 10.1371/journal.pone.0043764. Epub 2012 Aug 31.


Dietary n-3 polyunsaturated fatty acids (PUFA) decrease obesity-associated Th17 cell-mediated inflammation during colitis.

Monk JM, Hou TY, Turk HF, Weeks B, Wu C, McMurray DN, Chapkin RS.

PLoS One. 2012;7(11):e49739. doi: 10.1371/journal.pone.0049739. Epub 2012 Nov 16.


Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.


Chitooligosaccharide ameliorates diet-induced obesity in mice and affects adipose gene expression involved in adipogenesis and inflammation.

Choi EH, Yang HP, Chun HS.

Nutr Res. 2012 Mar;32(3):218-28. doi: 10.1016/j.nutres.2012.02.004.


Oil from the marine zooplankton Calanus finmarchicus improves the cardiometabolic phenotype of diet-induced obese mice.

Höper AC, Salma W, Khalid AM, Hafstad AD, Sollie SJ, Raa J, Larsen TS, Aasum E.

Br J Nutr. 2013 Dec;110(12):2186-93. doi: 10.1017/S0007114513001839. Epub 2013 Jun 17.


n-3 PUFA: bioavailability and modulation of adipose tissue function.

Kopecky J, Rossmeisl M, Flachs P, Kuda O, Brauner P, Jilkova Z, Stankova B, Tvrzicka E, Bryhn M.

Proc Nutr Soc. 2009 Nov;68(4):361-9. doi: 10.1017/S0029665109990231. Epub 2009 Aug 24. Review.


Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation.

Kalupahana NS, Claycombe K, Newman SJ, Stewart T, Siriwardhana N, Matthan N, Lichtenstein AH, Moustaid-Moussa N.

J Nutr. 2010 Nov;140(11):1915-22. doi: 10.3945/jn.110.125732. Epub 2010 Sep 22.


Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.

Lazic M, Inzaugarat ME, Povero D, Zhao IC, Chen M, Nalbandian M, Miller YI, Cherñavsky AC, Feldstein AE, Sears DD.

PLoS One. 2014 Sep 24;9(9):e107658. doi: 10.1371/journal.pone.0107658. eCollection 2014.


High-fat diet action on adiposity, inflammation, and insulin sensitivity depends on the control low-fat diet.

Benoit B, Plaisancié P, Awada M, Géloën A, Estienne M, Capel F, Malpuech-Brugère C, Debard C, Pesenti S, Morio B, Vidal H, Rieusset J, Michalski MC.

Nutr Res. 2013 Nov;33(11):952-60. doi: 10.1016/j.nutres.2013.07.017. Epub 2013 Sep 14.


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