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Antidepressant effects of nortriptyline and escitalopram in the GENDEP study: is one better than the other?

Uher R, Mors O, McGuffin P.

Acta Psychiatr Scand. 2013 Apr;127(4):330. doi: 10.1111/acps.12068. No abstract available.


Escitalopram versus nortriptyline: how to let the clinical GENDEP data tell us what they contained.

Bech P, Allerup P, Larsen ER, Csillag C, Licht RW.

Acta Psychiatr Scand. 2013 Apr;127(4):328-9. doi: 10.1111/acps.12067. No abstract available.


Non-random dropout and the relative efficacy of escitalopram and nortriptyline in treating major depressive disorder.

Power RA, Muthén B, Henigsberg N, Mors O, Placentino A, Mendlewicz J, Maier W, McGuffin P, Lewis CM, Uher R.

J Psychiatr Res. 2012 Oct;46(10):1333-8. doi: 10.1016/j.jpsychires.2012.06.014. Epub 2012 Jul 6.


Antiplatelet effects of antidepressant treatment: a randomized comparison between escitalopram and nortriptyline.

Flöck A, Zobel A, Bauriedel G, Tuleta I, Hammerstingl C, Höfels S, Schuhmacher A, Maier W, Nickenig G, Skowasch D.

Thromb Res. 2010 Aug;126(2):e83-7. doi: 10.1016/j.thromres.2010.04.020.


Body weight as a predictor of antidepressant efficacy in the GENDEP project.

Uher R, Mors O, Hauser J, Rietschel M, Maier W, Kozel D, Henigsberg N, Souery D, Placentino A, Perroud N, Dernovsek MZ, Strohmaier J, Larsen ER, Zobel A, Leszczynska-Rodziewicz A, Kalember P, Pedrini L, Linotte S, Gunasinghe C, Aitchison KJ, McGuffin P, Farmer A.

J Affect Disord. 2009 Nov;118(1-3):147-54. doi: 10.1016/j.jad.2009.02.013. Epub 2009 Mar 9.


DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP.

Powell TR, Smith RG, Hackinger S, Schalkwyk LC, Uher R, McGuffin P, Mill J, Tansey KE.

Transl Psychiatry. 2013 Sep 3;3:e300. doi: 10.1038/tp.2013.73.


Transcriptomics and the mechanisms of antidepressant efficacy.

Hodgson K, Tansey KE, Powell TR, Coppola G, Uher R, Zvezdana Dernovšek M, Mors O, Hauser J, Souery D, Maier W, Henigsberg N, Rietschel M, Placentino A, Aitchison KJ, Craig IW, Farmer AE, Breen G, McGuffin P, Dobson R.

Eur Neuropsychopharmacol. 2016 Jan;26(1):105-12. doi: 10.1016/j.euroneuro.2015.10.009. Epub 2015 Nov 12.


Relapse Prevention in Major Depressive Disorder After Successful Acute Electroconvulsive Treatment: a 6-month Double-blind Comparison of Three Fixed Dosages of Escitalopram and a Fixed Dose of Nortriptyline - Lessons from a Failed Randomised Trial of the Danish University Antidepressant Group (DUAG-7).

Martiny K, Larsen ER, Licht RW, Nielsen CT, Damkier P, Refsgaard E, Lunde M, Straasø B, Christensen EM, Lolk A, Holmskov J, Sørensen CH, Brødsgaard I, Eftekhari SZ, Bendsen BB, Klysner R, Terp IM, Larsen JK, Vestergaard P, Buchholtz PE, Gram LF, Bech P; Danish University Antidepressant Group (DUAG*).

Pharmacopsychiatry. 2015 Nov;48(7):274-8. doi: 10.1055/s-0035-1565063. Epub 2015 Nov 3.


Genome-wide pharmacogenetics of antidepressant response in the GENDEP project.

Uher R, Perroud N, Ng MY, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Zagar T, Czerski PM, Jerman B, Larsen ER, Schulze TG, Zobel A, Cohen-Woods S, Pirlo K, Butler AW, Muglia P, Barnes MR, Lathrop M, Farmer A, Breen G, Aitchison KJ, Craig I, Lewis CM, McGuffin P.

Am J Psychiatry. 2010 May;167(5):555-64. doi: 10.1176/appi.ajp.2009.09070932. Epub 2010 Apr 1.


Variation in GNB3 predicts response and adverse reactions to antidepressants.

Keers R, Bonvicini C, Scassellati C, Uher R, Placentino A, Giovannini C, Rietschel M, Henigsberg N, Kozel D, Mors O, Maier W, Hauser J, Souery D, Mendlewicz J, Schmäl C, Zobel A, Larsen ER, Szczepankiewicz A, Kovacic Z, Elkin A, Craig I, McGuffin P, Farmer AE, Aitchison KJ, Gennarelli M.

J Psychopharmacol. 2011 Jul;25(7):867-74. doi: 10.1177/0269881110376683. Epub 2010 Sep 8.


Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project.

Perroud N, Aitchison KJ, Uher R, Smith R, Huezo-Diaz P, Marusic A, Maier W, Mors O, Placentino A, Henigsberg N, Rietschel M, Hauser J, Souery D, Kapelski P, Bonvicini C, Zobel A, Jorgensen L, Petrovic A, Kalember P, Schulze TG, Gupta B, Gray J, Lewis CM, Farmer AE, McGuffin P, Craig I.

Neuropsychopharmacology. 2009 Nov;34(12):2517-28. doi: 10.1038/npp.2009.81. Epub 2009 Jul 29.


Combining clinical variables to optimize prediction of antidepressant treatment outcomes.

Iniesta R, Malki K, Maier W, Rietschel M, Mors O, Hauser J, Henigsberg N, Dernovsek MZ, Souery D, Stahl D, Dobson R, Aitchison KJ, Farmer A, Lewis CM, McGuffin P, Uher R.

J Psychiatr Res. 2016 Jul;78:94-102. doi: 10.1016/j.jpsychires.2016.03.016. Epub 2016 Apr 1.


Stressful life events, cognitive symptoms of depression and response to antidepressants in GENDEP.

Keers R, Uher R, Gupta B, Rietschel M, Schulze TG, Hauser J, Skibinska M, Henigsberg N, Kalember P, Maier W, Zobel A, Mors O, Kristensen AS, Kozel D, Giovannini C, Mendlewicz J, Kumar S, McGuffin P, Farmer AE, Aitchison KJ.

J Affect Disord. 2010 Dec;127(1-3):337-42. doi: 10.1016/j.jad.2010.06.011. Epub 2010 Jul 6.


Antidepressant-dependent mRNA changes in mouse associated with hippocampal neurogenesis in a mouse model of depression.

Malki K, Lourdusamy A, Binder E, Payá-Cano J, Sluyter F, Craig I, Keers R, McGuffin P, Uher R, Schalkwyk LC.

Pharmacogenet Genomics. 2012 Nov;22(11):765-76. doi: 10.1097/FPC.0b013e328356fa90.


A comparison of mirtazapine and nortriptyline following two consecutive failed medication treatments for depressed outpatients: a STAR*D report.

Fava M, Rush AJ, Wisniewski SR, Nierenberg AA, Alpert JE, McGrath PJ, Thase ME, Warden D, Biggs M, Luther JF, Niederehe G, Ritz L, Trivedi MH.

Am J Psychiatry. 2006 Jul;163(7):1161-72.


Depression symptom dimensions as predictors of antidepressant treatment outcome: replicable evidence for interest-activity symptoms.

Uher R, Perlis RH, Henigsberg N, Zobel A, Rietschel M, Mors O, Hauser J, Dernovsek MZ, Souery D, Bajs M, Maier W, Aitchison KJ, Farmer A, McGuffin P.

Psychol Med. 2012 May;42(5):967-80. doi: 10.1017/S0033291711001905. Epub 2011 Sep 20.


Reduced cardio-respiratory coupling after treatment with nortriptyline in contrast to S-citalopram.

Bär KJ, Schuhmacher A, Höfels S, Schulz S, Voss A, Yeragani VK, Maier W, Zobel A.

J Affect Disord. 2010 Dec;127(1-3):266-73. doi: 10.1016/j.jad.2010.05.010. Epub 2010 Jun 9.


Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants.

Malki K, Uher R, Paya-Cano J, Binder E, Rietschel M, Zobel A, Mors O, Hauser J, Henigsberg N, Jerman B, Souery D, Placentino A, Ng MY, Cohen-Woods S, Sluyter F, Farmer A, Aitchison KJ, Craig IW, Lewis CM, McGuffin P, Schalkwyk LC.

Biol Psychiatry. 2011 Feb 15;69(4):360-5. doi: 10.1016/j.biopsych.2010.08.011. Epub 2010 Oct 20.


A new role for nortriptyline in depression associated with vascular disease?

Kunte H, Rentzsch J, Kronenberg G.

Am J Psychiatry. 2015 Feb 1;172(2):201. doi: 10.1176/appi.ajp.2014.14070926. No abstract available.


[Escitalopram versus citalopram in true depression. Review of studies do not support clinically relevant differences of the effect].

Schwan S, Hallberg P.

Lakartidningen. 2009 Mar 18-24;106(12):858-61. Review. Swedish. No abstract available.


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