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Items: 1 to 20 of 107

1.

The angiotensin II type I receptor blocker olmesartan inhibits the growth of pancreatic cancer by targeting stellate cell activities in mice.

Masamune A, Hamada S, Kikuta K, Takikawa T, Miura S, Nakano E, Shimosegawa T.

Scand J Gastroenterol. 2013 May;48(5):602-9. doi: 10.3109/00365521.2013.777776. Epub 2013 Mar 11.

PMID:
23477656
2.

Pirfenidone inhibits pancreatic cancer desmoplasia by regulating stellate cells.

Kozono S, Ohuchida K, Eguchi D, Ikenaga N, Fujiwara K, Cui L, Mizumoto K, Tanaka M.

Cancer Res. 2013 Apr 1;73(7):2345-56. doi: 10.1158/0008-5472.CAN-12-3180. Epub 2013 Jan 24.

3.

Effects of octreotide on activated pancreatic stellate cell-induced pancreas graft fibrosis in rats.

Long D, Lu J, Luo L, Guo Y, Li C, Wu W, Shan J, Li L, Li S, Li Y, Lin T, Feng L.

J Surg Res. 2012 Jul;176(1):248-59. doi: 10.1016/j.jss.2011.06.009. Epub 2011 Jul 5. Erratum in: J Surg Res. 2013 Apr;180(2):368.

PMID:
21816420
4.

Retinoic Acid Ameliorates Pancreatic Fibrosis and Inhibits the Activation of Pancreatic Stellate Cells in Mice with Experimental Chronic Pancreatitis via Suppressing the Wnt/β-Catenin Signaling Pathway.

Xiao W, Jiang W, Shen J, Yin G, Fan Y, Wu D, Qiu L, Yu G, Xing M, Hu G, Wang X, Wan R.

PLoS One. 2015 Nov 10;10(11):e0141462. doi: 10.1371/journal.pone.0141462. eCollection 2015.

5.

Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells.

Kikuta K, Masamune A, Watanabe T, Ariga H, Itoh H, Hamada S, Satoh K, Egawa S, Unno M, Shimosegawa T.

Biochem Biophys Res Commun. 2010 Dec 17;403(3-4):380-4. doi: 10.1016/j.bbrc.2010.11.040. Epub 2010 Nov 20.

PMID:
21081113
6.

Antihypertensive, insulin-sensitising and renoprotective effects of a novel, potent and long-acting angiotensin II type 1 receptor blocker, azilsartan medoxomil, in rat and dog models.

Kusumoto K, Igata H, Ojima M, Tsuboi A, Imanishi M, Yamaguchi F, Sakamoto H, Kuroita T, Kawaguchi N, Nishigaki N, Nagaya H.

Eur J Pharmacol. 2011 Nov 1;669(1-3):84-93. doi: 10.1016/j.ejphar.2011.07.014. Epub 2011 Jul 28.

PMID:
21816148
7.

Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells.

Bachem MG, Schünemann M, Ramadani M, Siech M, Beger H, Buck A, Zhou S, Schmid-Kotsas A, Adler G.

Gastroenterology. 2005 Apr;128(4):907-21.

PMID:
15825074
8.

Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity.

Erkan M, Kleeff J, Gorbachevski A, Reiser C, Mitkus T, Esposito I, Giese T, Büchler MW, Giese NA, Friess H.

Gastroenterology. 2007 Apr;132(4):1447-64. Epub 2007 Jan 25.

PMID:
17408641
9.

Salutary effects of attenuation of angiotensin II on coronary perivascular fibrosis associated with insulin resistance and obesity.

Zaman AK, Fujii S, Goto D, Furumoto T, Mishima T, Nakai Y, Dong J, Imagawa S, Sobel BE, Kitabatake A.

J Mol Cell Cardiol. 2004 Aug;37(2):525-35.

PMID:
15276022
11.

Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells.

Hamada S, Masamune A, Takikawa T, Suzuki N, Kikuta K, Hirota M, Hamada H, Kobune M, Satoh K, Shimosegawa T.

Biochem Biophys Res Commun. 2012 May 4;421(2):349-54. doi: 10.1016/j.bbrc.2012.04.014. Epub 2012 Apr 9.

PMID:
22510406
12.

Trametinib and dactolisib but not regorafenib exert antiproliferative effects on rat pancreatic stellate cells.

Witteck L, Jaster R.

Hepatobiliary Pancreat Dis Int. 2015 Dec;14(6):642-50.

PMID:
26663013
13.

Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan.

Fan YY, Baba R, Nagai Y, Miyatake A, Hosomi N, Kimura S, Sun GP, Kohno M, Fujita M, Abe Y, Nishiyama A.

Hypertens Res. 2006 Mar;29(3):169-78.

PMID:
16755152
14.

Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells.

Apte MV, Park S, Phillips PA, Santucci N, Goldstein D, Kumar RK, Ramm GA, Buchler M, Friess H, McCarroll JA, Keogh G, Merrett N, Pirola R, Wilson JS.

Pancreas. 2004 Oct;29(3):179-87.

PMID:
15367883
15.

Fibrinogen induces cytokine and collagen production in pancreatic stellate cells.

Masamune A, Kikuta K, Watanabe T, Satoh K, Hirota M, Hamada S, Shimosegawa T.

Gut. 2009 Apr;58(4):550-9. doi: 10.1136/gut.2008.154401. Epub 2008 Dec 3.

PMID:
19052021
16.

Angiotensin II type 1 receptor blocker inhibits fibrosis in rat nonalcoholic steatohepatitis.

Hirose A, Ono M, Saibara T, Nozaki Y, Masuda K, Yoshioka A, Takahashi M, Akisawa N, Iwasaki S, Oben JA, Onishi S.

Hepatology. 2007 Jun;45(6):1375-81.

PMID:
17518368
17.

Calcium channel blocker azelnidipine reduces glucose intolerance in diabetic mice via different mechanism than angiotensin receptor blocker olmesartan.

Iwai M, Li HS, Chen R, Shiuchi T, Wu L, Min LJ, Li JM, Tsuda M, Suzuki J, Tomono Y, Tomochika H, Mogi M, Horiuchi M.

J Pharmacol Exp Ther. 2006 Dec;319(3):1081-7. Epub 2006 Sep 21.

18.

Pancreatic stellate cells potentiate proinvasive effects of SERPINE2 expression in pancreatic cancer xenograft tumors.

Neesse A, Wagner M, Ellenrieder V, Bachem M, Gress TM, Buchholz M.

Pancreatology. 2007;7(4):380-5. Epub 2007 Aug 14.

PMID:
17703087
19.

Olmesartan, a novel angiotensin II type 1 receptor antagonist, reduces severity of atherosclerosis in apolipoprotein E deficient mice associated with reducing superoxide production.

Shimada K, Murayama T, Yokode M, Kita T, Fujita M, Kishimoto C.

Nutr Metab Cardiovasc Dis. 2011 Sep;21(9):672-8. doi: 10.1016/j.numecd.2009.12.016. Epub 2010 Apr 15.

PMID:
20399087
20.

Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects.

Kurita S, Takamura T, Ota T, Matsuzawa-Nagata N, Kita Y, Uno M, Nabemoto S, Ishikura K, Misu H, Ando H, Zen Y, Nakanuma Y, Kaneko S.

Eur J Pharmacol. 2008 Jul 7;588(2-3):316-24. doi: 10.1016/j.ejphar.2008.04.028. Epub 2008 Apr 16.

PMID:
18501344

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