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Items: 1 to 20 of 139

1.

Remarkable role of indoleamine 2,3-dioxygenase and tryptophan metabolites in infectious diseases: potential role in macrophage-mediated inflammatory diseases.

Murakami Y, Hoshi M, Imamura Y, Arioka Y, Yamamoto Y, Saito K.

Mediators Inflamm. 2013;2013:391984. doi: 10.1155/2013/391984. Epub 2013 Feb 18. Review.

2.

Role of indoleamine 2,3-dioxygenase in health and disease.

Yeung AW, Terentis AC, King NJ, Thomas SR.

Clin Sci (Lond). 2015 Oct;129(7):601-72. doi: 10.1042/CS20140392. Review.

PMID:
26186743
3.

Persistent infectious diseases say - IDO. Role of indoleamine-2,3-dioxygenase in disease pathogenesis and implications for therapy.

Barth H, Raghuraman S.

Crit Rev Microbiol. 2014 Nov;40(4):360-8. doi: 10.3109/1040841X.2012.742037. Epub 2012 Nov 23. Review.

PMID:
23174025
4.

Amino acid deprivation links BLIMP-1 to the immunomodulatory enzyme indoleamine 2,3-dioxygenase.

Barnes NA, Stephenson SJ, Tooze RM, Doody GM.

J Immunol. 2009 Nov 1;183(9):5768-77. doi: 10.4049/jimmunol.0803480. Epub 2009 Oct 14.

5.

Emerging concepts on inhibitors of indoleamine 2,3-dioxygenase in rheumatic diseases.

Filippini P, Del Papa N, Sambataro D, Del Bufalo A, Locatelli F, Rutella S.

Curr Med Chem. 2012;19(31):5381-93. Review.

PMID:
22963664
6.

Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials.

Yuasa HJ, Ball HJ, Ho YF, Austin CJ, Whittington CM, Belov K, Maghzal GJ, Jermiin LS, Hunt NH.

Comp Biochem Physiol B Biochem Mol Biol. 2009 Jun;153(2):137-44.

PMID:
19402226
7.

Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone.

Wolowczuk I, Hennart B, Leloire A, Bessede A, Soichot M, Taront S, Caiazzo R, Raverdy V, Pigeyre M; ABOS Consortium., Guillemin GJ, Allorge D, Pattou F, Froguel P, Poulain-Godefroy O.

Am J Physiol Regul Integr Comp Physiol. 2012 Jul 15;303(2):R135-43. doi: 10.1152/ajpregu.00373.2011. Epub 2012 May 16.

8.

Investigation of the kynurenine pathway in Indoleamine 2, 3 dioxygenase deficient mice with inflammatory arthritis.

Kolodziej L.

Transgenic Res. 2013 Oct;22(5):1049-54. doi: 10.1007/s11248-013-9696-5. Epub 2013 Feb 17.

9.

Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolism.

Takikawa O.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):12-9. Epub 2005 Sep 15. Review.

PMID:
16176799
10.

Activation of indoleamine 2,3-dioxygenase in patients with scrub typhus and its role in growth restriction of Orientia tsutsugamushi.

Prachason T, Konhan K, Pongnarin P, Chatsiricharoenkul S, Suputtamongkol Y, Limwongse C.

PLoS Negl Trop Dis. 2012;6(7):e1731. doi: 10.1371/journal.pntd.0001731. Epub 2012 Jul 31.

11.

The interplay between indoleamine 2,3-dioxygenase 1 (IDO1) and cyclooxygenase (COX)-2 in chronic inflammation and cancer.

Cesario A, Rocca B, Rutella S.

Curr Med Chem. 2011;18(15):2263-71. doi: 0929-8673/11 $58.00+.00. Review.

PMID:
21517752
12.

Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors.

Koblish HK, Hansbury MJ, Bowman KJ, Yang G, Neilan CL, Haley PJ, Burn TC, Waeltz P, Sparks RB, Yue EW, Combs AP, Scherle PA, Vaddi K, Fridman JS.

Mol Cancer Ther. 2010 Feb;9(2):489-98. doi: 10.1158/1535-7163.MCT-09-0628. Epub 2010 Feb 2.

13.

Insights into therapy: tryptophan oxidation and HIV infection.

Murray MF.

Sci Transl Med. 2010 May 19;2(32):32ps23. doi: 10.1126/scitranslmed.3001082.

PMID:
20484729
14.

The potential of targeting indoleamine 2,3-dioxygenase for cancer treatment.

Gostner JM, Becker K, Überall F, Fuchs D.

Expert Opin Ther Targets. 2015 May;19(5):605-15. doi: 10.1517/14728222.2014.995092. Epub 2015 Feb 15. Review.

PMID:
25684107
15.

The IDO1-induced kynurenines play a major role in the antimicrobial effect of human myeloid cells against Listeria monocytogenes.

Niño-Castro A, Abdullah Z, Popov A, Thabet Y, Beyer M, Knolle P, Domann E, Chakraborty T, Schmidt SV, Schultze JL.

Innate Immun. 2014 May;20(4):401-11. doi: 10.1177/1753425913496442. Epub 2013 Aug 12.

PMID:
23940074
16.

Heme-binding-mediated negative regulation of the tryptophan metabolic enzyme indoleamine 2,3-dioxygenase 1 (IDO1) by IDO2.

Lee YK, Lee HB, Shin DM, Kang MJ, Yi EC, Noh S, Lee J, Lee C, Min CK, Choi EY.

Exp Mol Med. 2014 Nov 14;46:e121. doi: 10.1038/emm.2014.69.

17.

Role of indoleamine 2,3-dioxygenase in antimicrobial defence and immuno-regulation: tryptophan depletion versus production of toxic kynurenines.

MacKenzie CR, Heseler K, Müller A, Däubener W.

Curr Drug Metab. 2007 Apr;8(3):237-44. Review.

PMID:
17430112
18.

Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells.

Iachininoto MG, Nuzzolo ER, Bonanno G, Mariotti A, Procoli A, Locatelli F, De Cristofaro R, Rutella S.

Molecules. 2013 Aug 22;18(9):10132-45. doi: 10.3390/molecules180910132.

19.

Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway.

Ball HJ, Yuasa HJ, Austin CJ, Weiser S, Hunt NH.

Int J Biochem Cell Biol. 2009 Mar;41(3):467-71. doi: 10.1016/j.biocel.2008.01.005. Epub 2008 Jan 11. Review.

PMID:
18282734
20.

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity.

Liu X, Shin N, Koblish HK, Yang G, Wang Q, Wang K, Leffet L, Hansbury MJ, Thomas B, Rupar M, Waeltz P, Bowman KJ, Polam P, Sparks RB, Yue EW, Li Y, Wynn R, Fridman JS, Burn TC, Combs AP, Newton RC, Scherle PA.

Blood. 2010 Apr 29;115(17):3520-30. doi: 10.1182/blood-2009-09-246124. Epub 2010 Mar 2.

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