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Items: 1 to 20 of 187

1.

Dissecting paclitaxel-microtubule association: quantitative assessment of the 2'-OH group.

Sharma S, Lagisetti C, Poliks B, Coates RM, Kingston DG, Bane S.

Biochemistry. 2013 Apr 2;52(13):2328-36. doi: 10.1021/bi400014t. Epub 2013 Mar 19.

2.

Enhanced microtubule binding and tubulin assembly properties of conformationally constrained paclitaxel derivatives.

Shanker N, Kingston DG, Ganesh T, Yang C, Alcaraz AA, Geballe MT, Banerjee A, McGee D, Snyder JP, Bane S.

Biochemistry. 2007 Oct 16;46(41):11514-27. Epub 2007 Sep 25.

PMID:
17892304
3.

Interaction of a fluorescent derivative of paclitaxel (Taxol) with microtubules and tubulin-colchicine.

Han Y, Chaudhary AG, Chordia MD, Sackett DL, Perez-Ramirez B, Kingston DG, Bane S.

Biochemistry. 1996 Nov 12;35(45):14173-83.

PMID:
8916903
4.

Interaction of a fluorescent paclitaxel analogue with tubulin.

Sengupta S, Boge TC, Georg GI, Himes RH.

Biochemistry. 1995 Sep 19;34(37):11889-94.

PMID:
7547924
5.

Differential assembly kinetics of alpha-tubulin isoforms in the presence of paclitaxel.

Banerjee A, Kasmala LT.

Biochem Biophys Res Commun. 1998 Apr 17;245(2):349-51.

PMID:
9571153
6.

Baccatin III induces assembly of purified tubulin into long microtubules.

Chatterjee SK, Barron DM, Vos S, Bane S.

Biochemistry. 2001 Jun 12;40(23):6964-70.

PMID:
11389612
7.

Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.

Canales A, Rodríguez-Salarichs J, Trigili C, Nieto L, Coderch C, Andreu JM, Paterson I, Jiménez-Barbero J, Díaz JF.

ACS Chem Biol. 2011 Aug 19;6(8):789-99. doi: 10.1021/cb200099u. Epub 2011 May 13.

PMID:
21539341
8.
9.

Molecular dynamics simulation and free energy landscape methods in probing L215H, L217R and L225M βI-tubulin mutations causing paclitaxel resistance in cancer cells.

Tripathi S, Srivastava G, Sharma A.

Biochem Biophys Res Commun. 2016 Aug 5;476(4):273-9. doi: 10.1016/j.bbrc.2016.05.112. Epub 2016 May 24.

PMID:
27233604
10.

The quest for a simple bioactive analog of paclitaxel as a potential anticancer agent.

Kingston DG, Snyder JP.

Acc Chem Res. 2014 Aug 19;47(8):2682-91. doi: 10.1021/ar500203h. Epub 2014 Jul 23.

12.

Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of beta-tubulin (Asp26Glu) and less stable microtubules.

Hari M, Loganzo F, Annable T, Tan X, Musto S, Morilla DB, Nettles JH, Snyder JP, Greenberger LM.

Mol Cancer Ther. 2006 Feb;5(2):270-8.

13.

Design, synthesis and biological evaluation of paclitaxel-mimics possessing only the oxetane D-ring and side chain structures.

Chen XX, Gao F, Wang Q, Huang X, Wang D.

Fitoterapia. 2014 Jan;92:111-5. doi: 10.1016/j.fitote.2013.10.015. Epub 2013 Nov 6.

PMID:
24211350
14.

Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.

Khrapunovich-Baine M, Menon V, Verdier-Pinard P, Smith AB 3rd, Angeletti RH, Fiser A, Horwitz SB, Xiao H.

Biochemistry. 2009 Dec 15;48(49):11664-77. doi: 10.1021/bi901351q.

15.

Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.

Buey RM, Calvo E, Barasoain I, Pineda O, Edler MC, Matesanz R, Cerezo G, Vanderwal CD, Day BW, Sorensen EJ, López JA, Andreu JM, Hamel E, Díaz JF.

Nat Chem Biol. 2007 Feb;3(2):117-25. Epub 2007 Jan 7.

PMID:
17206139
16.

Equilibrium studies of a fluorescent paclitaxel derivative binding to microtubules.

Li Y, Edsall R Jr, Jagtap PG, Kingston DG, Bane S.

Biochemistry. 2000 Jan 25;39(3):616-23.

PMID:
10642187
17.

The solid state, solution and tubulin-bound conformations of agents that promote microtubule stabilization.

Jiménez-Barbero J, Amat-Guerri F, Snyder JP.

Curr Med Chem Anticancer Agents. 2002 Jan;2(1):91-122. Review.

PMID:
12678753
18.

Synthesis, modeling, and anti-tubulin activity of a D-seco paclitaxel analogue.

Barboni L, Giarlo G, Ricciutelli M, Ballini R, Georg GI, VanderVelde DG, Himes RH, Wang M, Lakdawala A, Snyder JP.

Org Lett. 2004 Feb 19;6(4):461-4.

PMID:
14961598
19.

Paclitaxel binding to human and murine MD-2.

Zimmer SM, Liu J, Clayton JL, Stephens DS, Snyder JP.

J Biol Chem. 2008 Oct 10;283(41):27916-26. doi: 10.1074/jbc.M802826200. Epub 2008 Jul 23.

20.

Probing the pore drug binding site of microtubules with fluorescent taxanes: evidence of two binding poses.

Barasoain I, García-Carril AM, Matesanz R, Maccari G, Trigili C, Mori M, Shi JZ, Fang WS, Andreu JM, Botta M, Díaz JF.

Chem Biol. 2010 Mar 26;17(3):243-53. doi: 10.1016/j.chembiol.2010.02.006.

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