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14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.

Tang S, Bao H, Zhang Y, Yao J, Yang P, Chen X.

PLoS One. 2013;8(3):e55268. doi: 10.1371/journal.pone.0055268.


14-3-3ε boosts bleomycin-induced DNA damage response by inhibiting the drug-resistant activity of MVP.

Tang S, Bai C, Yang P, Chen X.

J Proteome Res. 2013 Jun 7;12(6):2511-24. doi: 10.1021/pr301085c.


Quantitative proteomic dissection of a native 14-3-3ε interacting protein complex associated with hepatocellular carcinoma.

Bai C, Tang S, Bai C, Chen X.

Amino Acids. 2014 Apr;46(4):841-52. doi: 10.1007/s00726-013-1644-4.


Regulation of aldo-keto-reductase family 1 B10 by 14-3-3ε and their prognostic impact of hepatocellular carcinoma.

Liu TA, Jan YJ, Ko BS, Wu YJ, Lu YJ, Liang SM, Liu CC, Chen SC, Wang J, Shyue SK, Liou JY.

Oncotarget. 2015 Nov 17;6(36):38967-82. doi: 10.18632/oncotarget.5734.


Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1.

Yang L, Inokuchi S, Roh YS, Song J, Loomba R, Park EJ, Seki E.

Gastroenterology. 2013 May;144(5):1042-1054.e4. doi: 10.1053/j.gastro.2013.01.056.


MicroRNA-26b suppresses the NF-κB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3.

Zhao N, Wang R, Zhou L, Zhu Y, Gong J, Zhuang SM.

Mol Cancer. 2014 Feb 24;13:35. doi: 10.1186/1476-4598-13-35.


Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway.

Rahmutulla B, Matsushita K, Satoh M, Seimiya M, Tsuchida S, Kubo S, Shimada H, Ohtsuka M, Miyazaki M, Nomura F.

Oncotarget. 2014 May 15;5(9):2404-17.


Upregulation of focal adhesion kinase by 14-3-3ε via NFκB activation in hepatocellular carcinoma.

Ko BS, Jan YJ, Chang TC, Liang SM, Chen SC, Liu TA, Wu YM, Wang J, Liou JY.

Anticancer Agents Med Chem. 2013 May;13(4):555-62.


Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.

Yang X, Zou P, Yao J, Yun D, Bao H, Du R, Long J, Chen X.

J Proteome Res. 2010 Mar 5;9(3):1402-15. doi: 10.1021/pr900932y.


Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis.

Qi R, An H, Yu Y, Zhang M, Liu S, Xu H, Guo Z, Cheng T, Cao X.

Cancer Res. 2003 Dec 1;63(23):8323-9.


Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling.

Qi Z, Shen L, Zhou H, Jiang Y, Lan L, Luo L, Yin Z.

Cell Signal. 2014 Jul;26(7):1616-25. doi: 10.1016/j.cellsig.2014.03.015.


Interactions between extracellular signal-regulated protein kinase 1, 14-3-3epsilon, and heat shock factor 1 during stress.

Wang X, Grammatikakis N, Siganou A, Stevenson MA, Calderwood SK.

J Biol Chem. 2004 Nov 19;279(47):49460-9.


Down-regulation of CYLD as a trigger for NF-κB activation and a mechanism of apoptotic resistance in hepatocellular carcinoma cells.

Urbanik T, Köhler BC, Boger RJ, Wörns MA, Heeger S, Otto G, Hövelmeyer N, Galle PR, Schuchmann M, Waisman A, Schulze-Bergkamen H.

Int J Oncol. 2011 Jan;38(1):121-31.


Aberrant Polo-like kinase 1-Cdc25A pathway in metastatic hepatocellular carcinoma.

Wang XQ, Zhu YQ, Lui KS, Cai Q, Lu P, Poon RT.

Clin Cancer Res. 2008 Nov 1;14(21):6813-20. doi: 10.1158/1078-0432.CCR-08-0626.


CXC195 suppresses proliferation and inflammatory response in LPS-induced human hepatocellular carcinoma cells via regulating TLR4-MyD88-TAK1-mediated NF-κB and MAPK pathway.

Wang Y, Tu Q, Yan W, Xiao D, Zeng Z, Ouyang Y, Huang L, Cai J, Zeng X, Chen YJ, Liu A.

Biochem Biophys Res Commun. 2015 Jan 2;456(1):373-9. doi: 10.1016/j.bbrc.2014.11.090.


Involvement of DNA damage response pathways in hepatocellular carcinoma.

Yang SF, Chang CW, Wei RJ, Shiue YL, Wang SN, Yeh YT.

Biomed Res Int. 2014;2014:153867. doi: 10.1155/2014/153867. Review.


Overexpression of 14-3-3ε predicts tumour metastasis and poor survival in hepatocellular carcinoma.

Ko BS, Chang TC, Hsu C, Chen YC, Shen TL, Chen SC, Wang J, Wu KK, Jan YJ, Liou JY.

Histopathology. 2011 Apr;58(5):705-11. doi: 10.1111/j.1365-2559.2011.03789.x.


CAMK1 phosphoinositide signal-mediated protein sorting and transport network in human hepatocellular carcinoma (HCC) by biocomputation.

Wang L, Huang J, Jiang M, Chen Q, Jiang Z, Feng H.

Cell Biochem Biophys. 2014 Nov;70(2):1011-6. doi: 10.1007/s12013-014-0011-8.


Involvement of C-jun NH2-terminal kinase and apoptosis induced factor in apoptosis induced by deglycosylated bleomycin in laryngeal carcinoma cells.

Brahim S, Aroui S, Abid K, Kenani A.

Cell Biol Int. 2009 Sep;33(9):964-70. doi: 10.1016/j.cellbi.2009.06.022.


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